Validation of the questionnaire of olfactory disorders (QOD) for the Brazilian population.

BACKGROUND: The incidence of olfactory disorders has increased in recent years, mainly related to COVID-19 infection. In Brazil, over 37 million cases of COVID-19 have been reported, and approximately 10 % of those cases continue to experience olfactory disorders for more than one month. Despite the significant negative impact on well-being, there is currently no validated instrument to assess how olfactory disorders impact the quality of life in Brazil. OBJECTIVES: This study aimed to validate the Questionnaire of Olfactory Disorders (QOD) for Brazilian Portuguese. METHODS: The authors first performed translation, back-translation, expert review, pre-testing, psychometric evaluation and cultural adaptation of the English version of the questionnaire. To assure linguistic and conceptual equivalence of the translated questionnaire, 126 participants from two Brazilian states and varying degrees of olfactory loss answered the QOD and the World Health Organization Quality of Life bref (WHOQOL-bref) questionnaires. The University of Pennsylvania Smell Identification Test (UPSIT®) was used to quantify the olfactory loss. Furthermore, to evaluate the reliability of the Portuguese version a test-retest was performed on a subgroup of patients. The authors observed a high Cronbach's alpha (α = 0.86) for internal consistency of the quality of Life (QOD-QOL) statements. FINDINGS: As expected, there was a negative correlation between QOD-QOL and UPSIT® (Spearman's ρ = -0.275, p = 0.002), since QOL score increases and UPSIT® score decreases with worsening of olfactory function. Correlations were moderate between QOD-QOL and WHOQOL-bref mean (Spearman's ρ = -0.374, p < 0.001) and weak to moderate between the QOD-QOL and Visual Analog Scale of the QOD regarding professional life, leisure, and private life (Spearman's ρ = -0.316, p = 0.000; Spearman's ρ = -0.293, p = 0.001; Spearman's ρ = -0.261, p = 0.004; respectively). CONCLUSION: In conclusion, the authors have demonstrated a high internal consistency and validity of the Brazilian Portuguese version of the QOD for evaluating the quality of life in individuals with olfactory disorders.

Análise da cobertura vacinal e a prevalência de internações por doenças do trato respiratório por agentes imunopreveníveis no período de janeiro de 2015 a julho de 2020 / Analysis of vaccine coverage and prevalence of hospitalizations by respiratory tract vaccine-preventable diseases in the period from january 2015 to july 2020

Introdução: as infecções respiratórias das vias aéreas são frequentes no nosso meio. O combate dessas infecções ocorre por meio da introdução dos antimicrobianos, quando indicados, e a profilaxia através da imunização, reduzindo a incidência das infecções e suas complicações. Objetivo: avaliar a cobertura vacinal para agentes causadores de infecções do trato respiratório e a prevalência de internações por essas afecções no Brasil no período de 2015 a 2020. Metodologia: trata-se de um estudo epidemiológico descritivo, cujos dados foram obtidos por meio do banco de dados proveniente do DATASUS, Sistema de Internação Hospitalar e Sistema de Informação do Programa Nacional de Imunizações. A seleção ocorreu por meio dos registros de indivíduos que foram imunizados no Brasil, por região e por ano de imunização das vacinas Pneumocócica, Pneumocócica 1º reforço, Tríplice viral D1, Tríplice viral 2, Tetra Viral, Pentavalente e Influenza. Resultados: ao decorrer dos anos, observou-se uma redução significativa da cobertura vacinal de todas as vacinas analisadas, com a região Norte apresentando o menor registro em todos os anos. Em relação a taxa de internações por pneumonia, a região Sudeste obteve as maiores taxas. Houve um aumento importante de internamentos por influenza na região Centro-Oeste em 2019. As taxas de internação por sarampo aumentaram significativamente no ano de 2018, principalmente na região Norte. Conclusão: apesar da redução progressiva nas taxas de cobertura vacinal das regiões brasileiras nos últimos anos, as taxas de internação para pneumonia e influenza tendem a queda, com aumento mais expressivo dos internamentos por sarampo no período analisado.

Introduction: respiratory airway infections are frequent infections. These infections are fought through use of antimicrobials, when indicated, and prophylaxis is done through immunization, reducing the incidence of infections and their complications. Objective: to evaluate vaccine coverage for agents responsible for respiratory tract infections and the prevalence of hospitalizations for these conditions in Brazil from 2015 to 2020. Methods: This is a descriptive epidemiological study. Data were obtained through the database from the Department of Informatics of SUS, Hospitalization System and Information System from the National Vaccination Program. Selection was conducted through analysis of the records of individuals who were vaccinated in Brazil, by region and by year of vaccination for the Pneumococcal and Pneumococcal 1st booster dose vaccines, first and second doses for Triple Viral vaccine, Tetra Viral vaccine, Pentavalent vaccine and influenza. Expected Results: over the years, there has been a significant reduction in vaccination coverage, with the Northern brazilian presenting the lowest record in all years. Regarding the rate of hospitalizations for pneumonia, the Southeastern had the highest rates. Assessing influenza, there was a more significant increase in the Midwest. Measles hospitalization rates increased significantly in 2018, especially North, despite disease eradication in 2016, with a parallel registry of reduction in vaccination coverage in the period analysed. Conclusion: Despite the progressive reduction in vaccination coverage rates in Brazilian in recent years, the hospitalization rates for pneumonia and influenza tend to fall, with a more expressive increase in hospitalizations for measles in the analyzed period.