RESUMO
BACKGROUND: Previous studies have shown that air pollution particulate matter (PM) is associated with an increased risk for myocardial infarction. The effects of air pollution on the risk of ST-elevation myocardial infarction (STEMI), in particular the role of gaseous air pollutants such as NO2 and O3 and the susceptibility of specific populations, are still under debate. METHODS: All patients entered in the Belgian prospective STEMI registry between 2009 and 2013 were included. Based on a validated spatial interpolation model from the Belgian Environment Agency, a national index was used to address the background level of air pollution exposure of Belgian population. A time-stratified and temperature-matched case-crossover analysis of the risk of STEMI was performed. RESULTS: A total of 11,428 STEMI patients were included in the study. Each 10µg/m3 increase in PM10, PM2.5 and NO2 was associated with an increased odds ratio (ORs) of STEMI of 1.026 (CI 95%: 1.005-1.048), 1.028 (CI 95%: 1.003-1.054) and 1.051 (CI 95%: 1.018-1.084), respectively. No effect of O3 was found. STEMI was associated with PM10 exposure in patients ≥75y.o. (OR: 1.046, CI 95%: 1.002-1.092) and with NO2 in patients ≤54y.o. (OR: 1.071, CI 95%: 1.010-1.136). No effect of air pollution on cardiac arrest or in-hospital STEMI mortality was found. CONCLUSION: PM2.5 and NO2 exposures incrementally increase the risk of STEMI. The risk related to PM appears to be greater in the elderly, while younger patients appear to be more susceptible to NO2 exposure.
Assuntos
Poluição do Ar/efeitos adversos , Exposição Ambiental/efeitos adversos , Sistema de Registros , Infarto do Miocárdio com Supradesnível do Segmento ST/induzido quimicamente , Infarto do Miocárdio com Supradesnível do Segmento ST/epidemiologia , Idoso , Poluentes Atmosféricos/efeitos adversos , Bélgica/epidemiologia , Estudos Cross-Over , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Material Particulado/efeitos adversos , Estudos Prospectivos , Infarto do Miocárdio com Supradesnível do Segmento ST/diagnósticoRESUMO
This report contains three cases of "disfagia lusoria" (right subclavy artery congenital anomaly). The patients are of different ages and they were diagnosed by X ray, arteriography and endoscopy. Surgical treatment was carried out in one of the patients due to the severity of the symptoms.
Assuntos
Transtornos de Deglutição/etiologia , Artéria Subclávia/anormalidades , Adolescente , Transtornos de Deglutição/terapia , Esôfago/diagnóstico por imagem , Humanos , Masculino , Pessoa de Meia-Idade , Radiografia , Artéria Subclávia/diagnóstico por imagemRESUMO
This report contains three cases of [quot ]disfagia lusoria[quot ] (right subclavy artery congenital anomaly). The patients are of different ages and they were diagnosed by X ray, arteriography and endoscopy. Surgical treatment was carried out in one of the patients due to the severity of the symptoms.
RESUMO
Se presentan tres casos de disfagia lusoria por arteria subclavia derecha aberrante, en paciente de distintas edades diagnosticados por contraste esofagico, arteriografia y endoscopia. En uno de los casos fue necesario el tratamiento quirurgico por la severidad de los sintomas
Assuntos
Adolescente , Pessoa de Meia-Idade , Humanos , Masculino , Transtornos de Deglutição , EsofagoscopiaRESUMO
Se presentan tres casos de disfagia lusoria por arteria subclavia derecha aberrante, en paciente de distintas edades diagnosticados por contraste esofagico, arteriografia y endoscopia. En uno de los casos fue necesario el tratamiento quirurgico por la severidad de los sintomas
Assuntos
Adolescente , Pessoa de Meia-Idade , Humanos , Masculino , Transtornos de Deglutição , EsofagoscopiaRESUMO
This booklet provides all prescribers with a set of treatment schedules covering most of the common conditions found in the country as part of the Malawi Essential Drugs Programme to promote the rational use of drugs
