Scalable and practical synthesis of clickable Cu-chelating azides.

A convenient and effective synthetic access to chelating azides was designed enabling the preparation of efficient clickable fluorescent derivatives. The comparison of the reactivity of these chelating azides to regular azides showcased the striking superiority of such derivatives for labeling applications.

Synthesis of a highly hydrophobic dimeric Lewis X containing glycolipid: a model for the study of homotypic carbohydrate--carbohydrate interaction.

This paper describes the synthesis of an octasaccharidic glycolipid 1 based on a stereo- and regioselective glycosylation between a Lewis X trisaccharidic donor and a pentasaccharidic acceptor. A highly hydrophobic lipid moiety of a new type was selected, making the compound 1 a good candidate for the study of the interaction of Lewis X functionalised vesicles.