RESUMO
The action of starch, saccharose, lactose and glucose in the atherogenic rations containing a physiological (5 per cent) or an elevated (21 per cent of the ration's mass) amount of fat on the lipids metabolism and complex carbohydrates, as well as on the morphological structures in the aorta and coronary vessels was studied. It is found that of all the carbohydrates studied the most marked metabolic disorders are produced by rations with saccharose and lactose. Morphological changes in the vessels were in evidence only in rats fed on rations with lactose or saccharose and with an elevated proportion of fat.
Assuntos
Arteriosclerose/induzido quimicamente , Carboidratos da Dieta/efeitos adversos , Animais , Arteriosclerose/metabolismo , Peso Corporal/efeitos dos fármacos , Metabolismo dos Carboidratos , Dieta Aterogênica , Metabolismo dos Lipídeos , Masculino , Ratos , Fatores de TempoRESUMO
Experiments conducted with albino rats have evidenced that under the effect of an atherogenic ration the level of lipids and cholesterol in the blood plasma and hepatic tissue and of sillac acids in the blood plasma increased. In the aortic intima the content of acid mucopolysaccharides was rising, this being attended by a concurrent swelling of the main interstitial substance and of the collagen fibers in the subendothelial layer. An addition of apple pectin or of cellulose to the atherogenic ration deferred the development of the mentioned changes.