[Benzonitrile and derivatives. Synthesis and pharmacological study of alkyl para-cyanophenoxy alkanoates on the central nervous system]. / Benzonitrile et dérivés. Synthèse et étude pharmacologique de para-cyanophénoxy-alcanoates d'alkyle sur le système nerveux central.

The results obtained by the pharmacological study of alkyl para-cyanophenoxy alkanoates seem to indicate that these derivatives present a sedative effect on the central nervous system. This activity increases with the number of methyl groups substituted, on ethyl para-cyanophenoxy acetate (except the motricity composent), most probably because of an increase in lipophily and therefore in the fixation on the central nervous system.

[Research on the psychopharmacologic profile of new barbiturics]. / Recherche du profil psychopharmacologique de nouveaux barbituriques.

The detection of psychopharmacological properties of 8 synthetic substances derived from barbituric didn't allow to consider the existence of well characterised psychotropic properties, particularly hypnotical, but only antalgic and sedative effects (or stimulating activity very low). If the presence of a benzyl substituent can confer an affinity for the nervous central system superior to the one developed when an allyl rest is in the same position, the presence of an OH or OCH3 in other place inverse the sedative character in stimulant potentiality.