RESUMO
This brief communication describes the characterization of a new allele, DRB1*1336.
Assuntos
Antígenos HLA-DR/genética , Antígenos HLA-DR/imunologia , Sequência de Bases , Feminino , Variação Genética , Cadeias HLA-DRB1 , Homozigoto , Humanos , Leucemia/genética , Dados de Sequência MolecularRESUMO
The cells of the uterine lining (endometrium) may grow, in a aggressive fashion and invade the muscular portion of the uterus. This disorder is nonmalignant but is a serious and disabling disease called adenomyosis. The author presents an actual evaluation of the diagnosis and treatment of adenomyosis with a revision of the world literature, a retrospective evaluation of personal cases that includes a very unusual case of adenomyosis
Assuntos
Humanos , Feminino , Adulto , Endometriose/diagnóstico , Endometriose/terapiaRESUMO
The cells of the uterine lining (endometrium) may grow, in a aggressive fashion and invade the muscular portion of the uterus. This disorder is nonmalignant but is a serious and disabling disease called adenomyosis. The author presents an actual evaluation of the diagnosis and treatment of adenomyosis with a revision of the world literature, a retrospective evaluation of personal cases that includes a very unusual case of adenomyosis.
Assuntos
Endometriose/diagnóstico , Endometriose/terapia , Adulto , Feminino , HumanosRESUMO
This study sought to determine risk factors for genital infection with papillomavirus (HPV) in Panamanian women 20-49 years old. Subjects were randomly selected from Herrera and Panama provinces (cervical cancer incidence 79 and 25/100,000, respectively). Participants were interviewed to determine sexual behavior. Cervicovaginal lavage specimens were obtained to test for HPV DNA by commercial dot blot hybridization. HPV-16/18 DNA was detected significantly more frequently (5%) in Panama than Herrera (2%) samples (P = .002). Clearly, infection with high-risk HPV types alone cannot account for the differences in cervical cancer incidence between the two populations. HPV-16/18 detection decreased with increasing years of sexual experience among all women in Panama and among women with multiple partners in Herrera. However, HPV-16/18 detection did not change with sexual experience among monogamous women in Herrera. Thus, the epidemiology of HPV is complex and reflects both virus- and population-specific factors.