A comparison of the effects of mediolateral surface and foot placement perturbations on balance control and response strategies during walking.

BACKGROUND: Balance perturbation studies during walking have improved our understanding of balance control in various destabilizing conditions. However, it is unknown to what extent balance recovery strategies can be generalized across different types of mediolateral balance perturbations. RESEARCH QUESTION: Do similar mediolateral perturbations (foot placement versus surface translation) have similar effects on balance control and corresponding balance response strategies? METHODS: Kinetic and kinematic data were previously collected during two separate studies, each with 15 young, healthy participants walking on an instrumented treadmill. In both studies, medial and lateral balance perturbations were applied at 80% of the gait cycle either by a treadmill surface translation or a pneumatic force applied to the swing foot. Differences in balance control (frontal plane whole body angular momentum) and balance response strategies (hip abduction moment, ankle inversion moment, center of pressure excursion and frontal plane trunk moment) between perturbed and unperturbed gait cycles were evaluated using statistical parametric mapping. RESULTS: Balance disruptions after foot placement perturbations were larger and sustained longer compared to surface translations. Changes in joint moment responses were also larger for the foot placement perturbations compared to the surface translation perturbations. Lateral hip, ankle, and trunk strategies were used to maintain balance after medial foot placement perturbations, while a trunk strategy was primarily used after surface translations. SIGNIFICANCE: Surface and foot placement perturbations influence balance control and corresponding response strategies differently. These results can help inform the development of perturbation-based balance training interventions aimed at reducing fall risk in clinical populations.

Muscle contributions to pre-swing biomechanical tasks influence swing leg mechanics in individuals post-stroke during walking.

BACKGROUND: Successful walking requires the execution of the pre-swing biomechanical tasks of body propulsion and leg swing initiation, which are often impaired post-stroke. While excess rectus femoris activity during swing is often associated with low knee flexion, previous work has suggested that deficits in propulsion and leg swing initiation may also contribute. The purpose of this study was to determine underlying causes of propulsion, leg swing initiation and knee flexion deficits in pre-swing and their link to stiff knee gait in individuals post-stroke. METHODS: Musculoskeletal models and forward dynamic simulations were developed for individuals post-stroke (n = 15) and healthy participants (n = 5). Linear regressions were used to evaluate the relationships between peak knee flexion, braking and propulsion symmetry, and individual muscle contributions to braking, propulsion, knee flexion in pre-swing, and leg swing initiation. RESULTS: Four out of fifteen of individuals post-stroke had higher plantarflexor contributions to propulsion and seven out of fifteen had higher vasti contributions to braking on their paretic leg relative to their nonparetic leg. Higher gastrocnemius contributions to propulsion predicted paretic propulsion symmetry (p = 0.005) while soleus contributions did not. Higher vasti contributions to braking in pre-swing predicted lower knee flexion (p = 0.022). The rectus femoris had minimal contributions to lower knee flexion acceleration in pre-swing compared to contributions from the vasti. However, for some individuals with low knee flexion, during pre-swing the rectus femoris absorbed more power and the iliopsoas contributed less power to the paretic leg. Total musculotendon work done on the paretic leg in pre-swing did not predict knee flexion during swing. CONCLUSIONS: These results emphasize the multiple causes of propulsion asymmetry in individuals post-stroke, including low plantarflexor contributions to propulsion, increased vasti contributions to braking and reliance on compensatory mechanisms. The results also show that the rectus femoris is not a major contributor to knee flexion in pre-swing, but absorbs more power from the paretic leg in pre-swing in some individuals with stiff knee gait. These results highlight the need to identify individual causes of propulsion and knee flexion deficits to design more effective rehabilitation strategies.

Individual muscle responses to mediolateral foot placement perturbations during walking.

Walking requires active control of frontal plane balance through adjustments to mediolateral foot placement and ground reaction forces. Previous work on mediolateral balance perturbations and control of foot placement has often focused on the bilateral gluteus medius muscles. However, additional leg and trunk muscles can influence foot placement by transferring power to the foot and pelvis during swing. Thus, the purpose of this study was to determine individual muscle contributions to balance control following medial and lateral foot placement perturbations. Ten participants performed treadmill walking trials which included perturbations immediately before randomized heel strikes. Muscle contributions to foot placement, ground reaction forces, trunk power and frontal plane external moments during representative perturbed and unperturbed gait cycles were estimated using musculoskeletal modeling and simulation. Net muscle contributions to foot placement were 61 ± 50% more medial during the first recovery step following lateral perturbations and 28 ± 14% less medial in the second recovery step following medial perturbations. Following lateral perturbations, the swing gluteus medius performed 57 ± 50% more lateral work and the stance gluteus medius performed 61 ± 50% more medial work on the foot. Following medial perturbations, the erector spinae performed 39 ± 33% less lateral work on the foot. Changes in net muscle work on the foot were inconsistent with changes in step width, suggesting that changes in step width were not due to active muscle control but rather the mechanical effect of the perturbation. These outcomes provide a foundation for future studies analyzing balance control in populations at risk of falling.

The influence of cognitive load on balance control during steady-state walking.

For an individual to successfully walk, they must maintain control of their dynamic balance. However, situations that require increased cognitive attention may impair an individual's ability to actively control their balance. While dual-task studies have analyzed walking-while-talking conditions, few studies have focused specifically on the influence of cognitive load on balance control. The purpose of this study was to assess how individuals prioritize their cognitive resources and control dynamic balance during dual-task conditions of varying difficulty. Young healthy adults (n = 15) performed two single-task conditions (spelling-while-standing and treadmill walking with no cognitive load) and three dual-task conditions (treadmill walking with increasing cognitive load: attentive listening and spelling short and long words backwards). Cognitive performance did not change between the single- and dual-task as measured by spelling percent error and response rate (p = 0.300). Balance control, assessed using the range of whole-body angular momentum, did not change between the no load and listening conditions, but decreased during the short and long spelling conditions (p < 0.001). These results highlight that in young adults balance control decreases during dual-task treadmill walking with increased cognitive loads, but their cognitive performance does not change. The decrease in balance control suggests that participants prioritized cognitive performance over balance control during these dual-task walking conditions. This work offers additional insight into the automaticity of walking and task-prioritization in healthy young individuals and provides the basis for future studies to determine differences in neurologically impaired populations.

Biomechanical response to mediolateral foot-placement perturbations during walking.

Dynamic balance in the frontal plane requires active control, which is accomplished largely through control of mediolateral foot placement. Individuals without mobility impairments have the ability to compensate for variability in foot-placement to maintain their balance; however, it is unknown how individuals respond to unexpected mediolateral perturbations to their foot placement that alter their balance control. The purpose of this study was to identify the biomechanical responses of individuals without mobility impairments to medial and lateral foot-placement perturbations during walking. Three-dimensional body segment kinematic and ground reaction force data were collected from 15 participants at 1.0 m/s and their self-selected speed on an instrumented treadmill. Dynamic balance was assessed by analyzing whole-body angular momentum in the frontal plane. We hypothesized that participants would respond to the perturbations with a combination of a lateral ankle strategy, hip adduction strategy and/or ankle push-off strategy to restore their balance. Overall, the medial perturbations adversely affected dynamic balance while lateral perturbations had little effect. Individuals responded to medial (lateral) perturbations with an increased (decreased) ankle inversion moment, which correlated to lateral (medial) shifts in their foot center of pressure. In addition, individuals responded to medial (lateral) perturbations with a decreased (slightly decreased) hip abduction moment. Contrary to our hypothesis, we did not observe an ankle push-off moment response but rather, a small response in the opposite direction. These results highlight the response of individuals without mobility impairments to unexpected foot-placement perturbations and provide a basis of comparison for those with impaired balance control.

Merged plantarflexor muscle activity is predictive of poor walking performance in post-stroke hemiparetic subjects.

Stroke is the leading cause of long-term disability and individuals post-stroke often experience impaired walking ability. The plantarflexor (PF) muscles are critical to walking through their contributions to the ground reaction forces and body segment energetics. Previous studies have shown muscle activity during walking can be grouped into co-excited muscle sets, or modules. Improper co-activation, or merging of modules, is a common impairment in individuals post-stroke. The purpose of this study was to determine the influence of merged PF modules on walking performance in individuals post stroke by examining balance control, body support and propulsion, and walking symmetry. Muscle modules were identified using non-negative matrix factorization to classify subjects as having an independent or merged PF module. The merged group had decreased balance control with a significantly higher frontal plane whole-body angular momentum than both the independent and control groups, while the independent and control groups were not significantly different. The merged group also had higher paretic braking and nonparetic propulsion than both the independent and control groups. These results remained when comparisons were limited to subjects who had the same number of modules, indicating this was not a general effect due to subjects with merged PF having fewer modules. It is likely that a merged PF module is indicative of general PF dysfunction even when some activation occurs at the appropriate time. These results suggest an independent PF module is critical to walking performance, and thus obtaining an independent PF module should be a crucial aim of stroke rehabilitation.