Assuntos
Miosite/induzido quimicamente , Penicilamina/efeitos adversos , Corticosteroides/uso terapêutico , Adulto , Idoso , Artrite Reumatoide/tratamento farmacológico , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Músculos/ultraestrutura , Miosite/diagnóstico , Miosite/terapia , Penicilamina/uso terapêutico , PlasmafereseRESUMO
The authors report 118 cases of brucella osteoarthritis, of which 61 were observed over the last ten years. The most frequent localisations are spinal (53.4%), sacro-iliac (34.5%) and coxofemoral (15.5%). The clinical aspects are not very specific. The general signs, frequent during coxitis and to a lesser degree in spondylodiscitis, are rare during sacro-iliac involvement. The radiological appearance is mainly characteristic in the spine. The diagnosis is usually made in the laboratory, depending on a search for specific antibodies and delayed hypersensitivity tests. Treatment requires the use of intra-tissular and intra-cellular penetrating antibiotics (tetracycline and rifampicin) administered for a long period. The course usually leads to a cure without sequelae.
Assuntos
Artrite Infecciosa/etiologia , Brucelose/complicações , Osteoartrite/etiologia , Artrite Infecciosa/diagnóstico , Artrite Infecciosa/tratamento farmacológico , Brucelose/diagnóstico , Brucelose/tratamento farmacológico , Humanos , Osteoartrite/diagnóstico , Osteoartrite/tratamento farmacológicoRESUMO
On the basis of a 50 case study, the authors insist on the difficulty of diagnosing lumbar intraspinal tumors seen in a rheumatological context. The increase in pain and spine and spine stiffness at night are the most significant semiological characteristics. A generally slight neurological deficiency is noted in 29 cases (58%) and 21 patients (41%) have a clinical picture identical to that of discal hernias. X-rays of the lumbar spine show signs of bone erosion in 24% of cases. Lumbar puncture furnishes major indications in 85.5% of cases. Contrast testing almost always demonstrates the presence of a tumor. Lumbar intraspinal tumors include a very wide variety of histological types, among which neurinomas, ependymomas and extra-dural malignant tumors are the most frequent.