[PROGNOSTIC STRATIFICATION OF CLINICALLY LOCALLY SPREAD CANCER OF PROSTATIC GLAND].

In 2002 ­ 2015 yrs in the clinic radical prostatectomy was performed in 403 patients for prostatic cancer, including those having stage cТ3 ­ in 102 (25.3%). Basing on analysis of main risk factors, a model of prognostic stratification of clinically locally spread prostatic cancer on three groups was created: with low risk ­ in the absence of data, confirming invasion into seminal vesicles (stage cТ3а), the prostate­specific antigen (PSA) content less than 20 ng/ml, degree of cellular differentiation of tumor (Glisson's index) in accordance to biopsy data ­ 6 and less; with intermediate risk ­ while presence of one of unfavorable prognostic factors (stage cТ3b), PSA 20 ng/ml and more, Glisson's index 7 and more; with high risk ­ while presence of two and more unfavorable prognostic factors. The follow­up duration was 50,6 mo at average. Biochemical recurrence in the groups while low, intermediate and high risk presence have occurred, accordingly, in 14.3, 37.1 and 62.3% patients (р<0.05), and its occurrence risk in patients while intermediate risk present is in 3,5 times, in high risk ­ in 9.9 times bigger, than in a low risk. Stratification may appear useful for practical physicians and investigators while choosing tactics of treatment in patients with prostatic cancer clinical stage ІІІ