RESUMO
Data from the CDC's Medical Monitoring Project indicate that the United States is on track to meet one of five National HIV/AIDS Strategy (NHAS) Quality of Life goals among cisgender Black women, specifically, hunger/food insecurity. Substantial work needs to be done to improve self-rated health and to decrease unmet need for mental health services. Enhanced and coordinated action are necessary to reach all Quality of Life goals in this NHAS priority population.
Assuntos
Negro ou Afro-Americano , Infecções por HIV , Qualidade de Vida , Humanos , Feminino , Infecções por HIV/psicologia , Estados Unidos , Negro ou Afro-Americano/psicologia , Adulto , Insegurança AlimentarAssuntos
Infecções por HIV/epidemiologia , Homossexualidade Masculina/estatística & dados numéricos , Programas de Rastreamento , Meio Social , Sífilis/epidemiologia , Adulto , Infecções por HIV/diagnóstico , Humanos , Masculino , Programas de Rastreamento/psicologia , Vigilância da População , São Francisco/epidemiologia , Inquéritos e QuestionáriosRESUMO
Host human leukocyte antigens (HLAs) integrated into the human immunodeficiency virus (HIV) type 1 envelope could theoretically determine, as in tissue transplants, whether HIV-1 is "rejected" by exposed susceptible persons, preventing transmission. HLA discordance (mismatch) was examined among 45 heterosexual partner pairs in which at least 1 partner was HIV-1 infected and exposure or transmission between partners had occurred. Immunologic discordance at class II HLA-DRB3 (present in the HIV donor partner but absent in the recipient partner) was associated with lack of transmission of HIV-1. Eight (35%) of 23 partner pairs in which HIV-1 transmission did not occur were immunologically discordant at HLA-DRB3, compared with 0 of 11 partner pairs in which HIV-1 transmission did occur (P=.027). Further investigation of the roles of class II HLAs in HIV-1 transmission and as possible components of HIV-1 vaccines should be pursued.
