Biocompatible Ag/Fe-Enhanced TiO2 Nanoparticles as an Effective Compound in Sunscreens.

In this work, valuable biocompatible Ag/Fe-enhanced TiO2 nanoparticles are comparatively prepared by a conventional wet chemistry method (sol-gel) and a rapid, efficient, hybrid unconventional method (microwave-assisted hydrothermal synthesis). In order to establish their application as effective compounds in sunscreens, the obtained powders were first structurally and morphologically characterized, analyses from which their nanodimensional character, crystalline structure and thermal behavior were highlighted. The evaluation of sunscreen effectiveness is based on the determination of the sun protection factor (SPF). It was observed that silver enhancing increases the SPF significantly, especially when compared to the pristine samples. The obtained Ag/Fe-enhanced TiO2 powders were also evaluated from the point of view of their biocompatibility on amniotic fluid stem cells, and the results indicated an enhance of cell proliferation when exposed to the synthesized nanostructures.

Rising demand sparked journey of home truths.

A switch to community treatment required a mental health trust to turn its centralized management system to a partnership model, as Dr. Shakil Malik and colleagues explain.

Cognitive impairment in HIV and HCV co-infected patients: a systematic review and meta-analysis.

Cognitive impairment has been well documented in HIV and hepatitis C virus (HCV) mono-infections. However, in the context of HIV/HCV co-infection the research is more limited. The aim of this systematic review was to describe the characteristics of cognitive impairment in HIV/HCV co-infection and to examine the differences in cognitive performance between HIV/HCV and HIV and HCV mono-infected patients. Of the 437 records initially screened, 24 papers met the inclusion criteria and were included in the systematic review. Four studies were included in the meta-analysis. Most studies indicated that HIV/HCV co-infected patients had a higher level of cognitive impairment than HIV mono-infected patients. Meta-analysis indicated, however, that HIV mono-infected patients had a significantly higher global deficit score than co-infected patients. The results also indicated that co-infected patients were more likely to be impaired in information processing speed than HIV mono-infected patients. These findings can be challenged by biasing factors such as the small number of studies, heterogeneity of the samples, and a large diversity of methodological procedures. Future research with consistent and comprehensive neuropsychological batteries and covering a greater diversity of risk factors is needed, in order to clarify the effects of both viruses on cognitive function and the mechanisms that underlie these effects. Because cognitive impairments may pose significant challenges to medication adherence, quality of life and overall functioning, such knowledge may have important implications to the planning and implementation of effective interventions aimed at optimising the clinical management of these infections.

Romanian psychiatric literature: analysis of accessibility and nature of Romanian psychiatric articles.

BACKGROUND: Romania is a low-income country of 22 million people and, currently, information regarding mental health research is limited. Romania is one of the last countries in eastern Europe not to have its own bibliographic biomedical database. AIM: To assess the content and quality of Romanian psychiatric research activity over time. METHOD: EMBASE (1980 to April 2008), MEDLINE (1950 to April 2008) and PsycINFO (1806 to April 2008) were systematically searched for psychiatric articles originating from Romania. The sample from PsycINFO was described. RESULTS: PsycINFO was by far the best source of Romanian mental health literature with a considerable increase in the publication activity since 2000 (PsycINFO identified 3236 hits, MEDLINE 549, EMBASE 139). Most papers are in English, but a sizeable minority are in Romanian (30%), French (4%) or Hungarian (4%). The main topics of interest are cognitive processes, creativity, schizophrenia and cognitive development and stress and are, according to PsycINFO's indexing, 'empirical studies'. Seventeen randomised trials were identified with all studies after 2000 being sponsored by industry. CONCLUSIONS: Surprisingly, and not in keeping with other studies of the literature of neighbouring countries, PsycINFO is the major source of psychiatric bibliographic records of this region. There are signs of a resurgence of research activity in Romania and as the number of local mental health workers increases we can expect more output. Industry is now funding evaluative studies in Romania. As everywhere, but perhaps more acutely in situations of severely limited research support, there is a difficult balance to be struck between benefiting support and losing independence.