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1.
Spinal Cord ; 55(2): 192-197, 2017 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-27897188

RESUMO

STUDY DESIGN: Sequential mixed method design. OBJECTIVES: Determine factors associated with community participation for individuals with spinal cord injury (SCI). SETTING: Queensland, Australia. METHODS: Phase I consisted of a quantitative telephone survey of 270 people who had sustained a SCI within the past 50 years. To verify and interpret survey findings, Phase II involved a qualitative investigation. One focus group, one dyadic and one in-depth interview were conducted with a separate sample of eight people who had sustained a SCI within the past 50 years. RESULTS: In Phase I, employment, paid or unpaid, was the strongest independent factor associated with community participation, whereas time since injury, completeness of injury, secondary conditions and functional independence were also independently associated. In Phase II, participants expressed that survey findings were consistent with their lived experiences. They explained that overall, they needed a strong reason to participate so that benefits outweigh the effort required to participate. Once out in the community, they recognised that other opportunities for participation arise. CONCLUSION: Rehabilitation services need to support individuals with SCI to find meaningful employment and to engage in activities that provide them with a strong reason to participate.


Assuntos
Participação da Comunidade/métodos , Traumatismos da Medula Espinal/diagnóstico , Traumatismos da Medula Espinal/epidemiologia , Adulto , Idoso , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Queensland/epidemiologia , Distribuição Aleatória , Traumatismos da Medula Espinal/reabilitação , Inquéritos e Questionários , Adulto Jovem
2.
BMJ Open ; 6(7): e011604, 2016 07 07.
Artigo em Inglês | MEDLINE | ID: mdl-27388361

RESUMO

INTRODUCTION: Surgical site infection (SSI) after minor skin excisions has a significant impact on patient morbidity and healthcare resources. Skin antisepsis prior to surgical incision is used to prevent SSI, and is performed routinely worldwide. However, in spite of the routine use of skin antisepsis, there is no consensus regarding which antiseptic agents are most effective. The AVALANCHE trial will compare Aqueous Versus Alcoholic Antisepsis with Chlorhexidine for Skin Excisions. METHODS AND ANALYSIS: The study design is a prospective, randomised controlled trial (RCT) with the aim of investigating the impact of two different antiseptic preparations on the incidence of superficial SSI in patients undergoing minor skin excisions. The intervention of 0.5% chlorhexidine gluconate (CHG) in 70% alcohol will be compared with that of 0.5% CHG in aqueous solution. The trial will be conducted in four Australian general practices over a 9-month period, with 920 participants to be recruited. Consecutive patients presenting for minor skin excisions will be eligible to participate. Randomisation will be on the level of the patient. The primary outcome is superficial SSI in the first 30 days following the excision. Secondary outcomes will be adverse effects, including anaphylaxis, skin irritation, contact dermatitis and rash and patterns of antibiotic resistance. ETHICS AND DISSEMINATION: The study has been approved by the James Cook University Human Research Ethics Committee (HREC). Findings will be disseminated in conference presentations and journals and through online electronic media. DISCUSSION: RCTs conducted in general practice differ from hospital-based projects in terms of feasibility, pragmatism and funding. The success of this trial will be cemented in the fact that the research question was established by a group of general practitioners who identified an interesting question which is relevant to their clinical practice and not answered by current evidence. TRIAL REGISTRATION NUMBER: ACTRN12615001045505; Pre-results.


Assuntos
Anti-Infecciosos Locais/administração & dosagem , Clorexidina/análogos & derivados , Etanol/administração & dosagem , Medicina Geral , Procedimentos Cirúrgicos Menores/métodos , Solventes/administração & dosagem , Infecção da Ferida Cirúrgica/prevenção & controle , Água/administração & dosagem , Clorexidina/administração & dosagem , Humanos , Queensland
3.
J Psychiatr Ment Health Nurs ; 22(4): 251-9, 2015 May.
Artigo em Inglês | MEDLINE | ID: mdl-25912269

RESUMO

The purpose of this research was to translate and to test an Indonesian version of the Impact of Event Scale-Revised (I-IES-R) as a measurement of psychological distress following a natural disaster. Sample of 30 Mt. Merapi residents participated in pilot testing and 110 survivors completed the test-retest of the I-IES-R. Exploratory factor analysis was used to determine construct validity, and Cronbach's alpha was used to assess reliability. The results of the translational phase of the study indicated that the Indonesian version of the IES-R captures the content of the original tool with appropriate adaptation for cultural differences. The Indonesian IES-R revealed a Cronbach's alpha of 0.90 for test and 0.92 for retest for the total score. In addition, the Cronbach alpha for subscales intrusion, avoidance and hyper arousal in the initial scale testing were 0.85, 0.75, and 0.74, respectively, and for the retest 0.88, 0.79, and 0.82, respectively. The reliability coefficient of the test-retest results was 0.75 [95% confidence interval = (0.64, 0.83)], and exploratory factor analysis identified three underlying factors: intrusion, avoidance, and hyper arousal. The I-IES-R can be considered a useful screening tool that can be used by mental health nurses to assess the psychological impact of natural disasters on survivors in Indonesia.


Assuntos
Desastres , Escalas de Graduação Psiquiátrica/normas , Psicometria/instrumentação , Estresse Psicológico/diagnóstico , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Estudos Transversais , Feminino , Humanos , Indonésia , Masculino , Pessoa de Meia-Idade , Reprodutibilidade dos Testes , Tradução , Erupções Vulcânicas , Adulto Jovem
4.
Aust Vet J ; 93(3): 84-8, 2015 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-25708792

RESUMO

OBJECTIVE: We investigated the relationship between a body mass index and tooth wear in the black flying-fox (Pteropus alecto Gould) to provide guidance on management of edentulous individuals by wildlife carers and veterinarians. METHODS: Flying-foxes brought into care because of injury were weighed, their forearms measured and the state of their teeth evaluated. Measurements were analysed by Chi-square, ANOVA, t-tests and regression to identify any relationship between the body mass index and the condition of canine and molar teeth, as well as in relation to sex and season. RESULTS: There was no statistically significant relationship between a bat's dentition state and the body mass index being used. CONCLUSIONS: In Townsville, the black flying-fox appears to experience a rapid decline in dental condition over time. Despite this, there is little indication that loss of teeth results in a decline in body condition. We attribute this to the dominance of floral foods in the bats' diet in Townsville and a lesser importance of hard fruit that requires intact dentition for consumption. Edentulousness on its own is not sufficient reason to euthanase black flying-foxes in either Townsville or similar relatively dry localities where blossom dominates the flying-fox diet.


Assuntos
Quirópteros , Desgaste dos Dentes/veterinária , Animais , Animais Selvagens , Índice de Massa Corporal , Conservação dos Recursos Naturais , Feminino , Masculino , Queensland , Estações do Ano , Desgaste dos Dentes/complicações
5.
Tech Coloproctol ; 18(11): 1009-16, 2014 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-24925353

RESUMO

BACKGROUND: Haemorrhoidectomy is the most effective and definitive treatment for grade 3 or 4 haemorrhoids despite being associated with considerable pain. The aim of this study was to search the literature, which compares outcomes of harmonic scalpel haemorrhoidectomy and traditional surgical procedures, and conduct a quantitative meta-analysis of the randomized trials. METHODS: Randomized controlled trials (RCTs) were identified from the major electronic databases using the keywords "harmonic scalpel haemorrhoidectomy" and "haemorrhoidectomy" and a quantitative meta-analysis conducted. The eight trials that met the inclusion criteria included 468 patients (233 in the harmonic scalpel group). Pain was the primary outcome measure, and other parameters assessed included duration of operation, length of hospital stay, time to return to work, and complications. RESULTS: Significantly, more patients returned to work in the first post-operative week, and pain scores were an average of one unit lower following harmonic scalpel haemorrhoidectomy. Generally, the incidence of complications in the harmonic scalpel group was less than half that found in conventional haemorrhoidectomy. There was no significant difference between the groups as regards operating time or length of hospital stay. Recurrence was not reported in any of the studies. CONCLUSIONS: The meta-analysis showed that harmonic scalpel haemorrhoidectomy is a safe and effective modality associated with less post-operative pain and a more rapid return to work than traditional surgery for haemorrhoids. Statistical heterogeneity was high; thus, it may be too early to place complete confidence in these results. Further RCTs are required.


Assuntos
Hemorroidectomia/instrumentação , Hemorroidas/cirurgia , Ensaios Clínicos Controlados Aleatórios como Assunto , Humanos , Resultado do Tratamento
6.
Rural Remote Health ; 11(1): 1511, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-21244193

RESUMO

INTRODUCTION: As medical education becomes more decentralised, and greater use is made of rural clinical schools and other dispersed sites, attention is being paid to the quality of the learning experiences across these sites. This article explores this issue by analysing the performance data of 4 cohorts of students in a dispersed clinical school model across 4 sites. The study is set in a newly established medical school in a regional area with a model of dispersed education, using data from the second to fifth cohorts to graduate from this school. METHODS: Summative assessment results of 4 graduating cohorts were examined over the final 2 years of the course. Two analyses were conducted: an analysis of variance of mean scores in both years across the 4 sites; and an analysis of the effect of moving to different clinical schools on the students' rank order of performance by use of the Kruskal-Wallis test. RESULTS: Analysis revealed no significant difference in the mean scores of the students studying at each site, and no significant differences overall in the median ranking across the years. Some small changes in the relative ranking of students were noticed, and workplace-based assessment scores in the final year were higher than the examination-based scores in the previous year. CONCLUSIONS: The choice of clinical school site for the final 2 years of an undergraduate rural medical school appears to have no effect on mean assessment scores and only a minor effect on the rank order of student scores. Workplace-based assessment produces higher scores but also has little effect on student rank order. Further studies are necessary to replicate these findings in other settings and demonstrate that student learning experiences in rural sites, while popular with students, translate into required learning outcomes, as measured by summative assessments.


Assuntos
Atitude do Pessoal de Saúde , Educação de Graduação em Medicina/organização & administração , Área de Atuação Profissional/estatística & dados numéricos , Serviços de Saúde Rural , Estudantes de Medicina/psicologia , Adulto , Estudos de Coortes , Currículo , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Avaliação de Processos e Resultados em Cuidados de Saúde , Queensland , Percepção Social , Estudantes de Medicina/estatística & dados numéricos , Inquéritos e Questionários , Recursos Humanos , Adulto Jovem
7.
Clin Microbiol Infect ; 17(8): 1216-22, 2011 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-21073630

RESUMO

Group A streptococci (GAS) are usually the predominant species in cases of bacteraemia caused by ß haemolytic streptococci (BHS). An increasing worldwide incidence of invasive disease from non-group A BHS has been reported. Little is known about the changing trends in invasive disease caused by BHS in Australia. North Queensland has a relatively large indigenous population, who experience significantly higher rates of group A-related disease than the non-indigenous population. This prospective study examined changing trends of disease from large colony BHS that group with A, B, C and G antisera over a 14-year period at the single large tertiary referral hospital in the area. We identified 392 bacteraemic episodes caused by BHS. GAS were most commonly isolated (49%), with adjusted rates remaining stable over the period. There was a significant increase in the incidence of non-neonatal bacteraemia caused by group B streptococci (GBS) over the study period (r = 0.58; p 0.030), largely driven by infection in older, non-indigenous women. Rates of bacteraemia caused by group C streptococci also experienced a modest, but significant, increase over time (r = 0.67; p 0.009). GAS, which had no predominant emm type, were seen most commonly in indigenous subjects (52%). Mortality rates ranged from 3.2% (group G) to 10.3% (group C), with a rate of 7.9% associated with group A disease. The marked rise in GBS disease has been noted worldwide, but the relatively low incidence in indigenous Australian patients has not been described before, despite the burden of well-recognized risk factors for GBS disease within this group.


Assuntos
Bacteriemia/epidemiologia , Infecções Estreptocócicas/epidemiologia , Streptococcus agalactiae/isolamento & purificação , Streptococcus pyogenes/isolamento & purificação , Streptococcus/isolamento & purificação , Bacteriemia/etnologia , Bacteriemia/microbiologia , Bacteriemia/mortalidade , Feminino , Humanos , Incidência , Masculino , Estudos Prospectivos , Queensland/epidemiologia , Infecções Estreptocócicas/etnologia , Infecções Estreptocócicas/microbiologia , Infecções Estreptocócicas/mortalidade , Streptococcus/classificação
8.
World J Surg ; 34(4): 797-807, 2010 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-20054541

RESUMO

BACKGROUND There is no consensus regarding the appropriate management of asymptomatic and minimally symptomatic patients with stage IV colorectal cancer and irresectable metastases. METHODS A literature search was conducted on Medline and Embase. Outcome measures included: survival; postoperative morbidity and mortality; complications from the primary tumor and the need for surgery to manage complications; the likelihood of curative surgery after initial response to primary therapy; and length of hospital stay. Quantitative meta-analysis was performed where appropriate. RESULTS Eight retrospective studies, including 1,062 patients, met the criteria for inclusion in this study. Meta-analysis has shown an improvement in the survival of patients managed with palliative resection of their primary tumor, with an estimated standardized median difference of 6.0 months (standardized difference, 0.55; 95% confidence interval (CI), 0.29, 0.82; p < 0.001). Patients managed with chemotherapy alone were 7.3 times more likely to have a complication from the primary tumor (95% CI, 1.7, 34.4; p = 0.008). There was no difference in the response rates to chemotherapy, making metastatic disease amendable to curative resection (0.85; 95% CI 0.40, 1.8; p = 0.662). CONCLUSIONS To date, only retrospective data are available, showing that palliative resection of the primary tumor in asymptomatic or minimally symptomatic patients with stage IV colorectal cancer is associated with longer survival. Resection of the primary tumor reduces the likelihood of complications from the primary tumor and avoids the need for emergency procedures.


Assuntos
Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Neoplasias Colorretais/tratamento farmacológico , Neoplasias Colorretais/patologia , Neoplasias Colorretais/cirurgia , Neoplasias Colorretais/mortalidade , Humanos , Metástase Neoplásica , Estadiamento de Neoplasias , Cuidados Paliativos , Prognóstico , Análise de Sobrevida
9.
Eat Weight Disord ; 14(1): 13-22, 2009 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-19367136

RESUMO

AIM: To explore the associations between changes in weight, eating disorder psychopathology and psychological distress in a community sample of women with eating disorders over two years. METHOD: One hundred and twenty two women identified with disordered eating in a baseline population survey agreed to participate in a follow-up study, of whom 87 (71%), mean age 28+/-6.2, completed the two-year follow-up. Body mass index, eating disorder psychopathology, psychological distress, and demographic details were assessed at both time points. RESULTS: Over the two years there was a mean weight gain of 1.76 kg (SD=7.03), 11 (13%) women lost > or =5 kg, 25 (29%) gained > or =5 kg, and 49 (58%) remained weight stable (i.e., within 5 kg of baseline weight). Comparisons between those who had lost, gained and remained weight stable showed few significant differences, however, women who remained weight stable were the least psychologically distressed at baseline and those who lost weight had the greatest reduction in shape concern. Body mass index at baseline, and change in level of binge eating episodes were not associated with weight change. CONCLUSIONS: Disordered eating behaviours have little influence on weight change over two years in community women with disordered eating. Low levels of psychological distress at baseline may promote weight stability. Concerns about shape are likely to increase with increased weight.


Assuntos
Imagem Corporal , Peso Corporal , Comportamento Alimentar , Transtornos da Alimentação e da Ingestão de Alimentos/psicologia , Sobrepeso/psicologia , Estresse Psicológico/etiologia , Adulto , Austrália , Índice de Massa Corporal , Bulimia , Feminino , Seguimentos , Nível de Saúde , Humanos , Saúde Mental , Obesidade/psicologia , Inquéritos e Questionários , Aumento de Peso , Redução de Peso , Adulto Jovem
10.
Tech Coloproctol ; 12(3): 229-39, 2008 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-18679571

RESUMO

BACKGROUND: To compare the surgical outcome of haemorrhoidectomy performed using LigaSure bipolar diathermy with conventional haemorrhoidectomy. METHODS: Only randomized and alternate allocated studies were included from the major electronic databases using the search terms "ligasure" and "haemorrhoids". Duration of operation, blood loss during operation, postoperative pain score, wound healing, in-hospital stay, time to return to normal activities and complications were assessed. RESULTS: The 11 trials contained a total of 1,046 patients; the largest study was based on 273 patients and two earlier studies were based on 34 patients. No significant gender mismatch between the groups was reported in any of the studies. The patients' ages were similar between groups in the studies, as was disease severity. All 11 studies reported a shorter duration of the operation when using LigaSure compared to the conventional technique (p<0.001). The postoperative pain score (p=0.001) and blood loss during operation (p=0.001) were significantly reduced. After LigaSure haemorrhoidectomy wound healing (p=0.004) and the return to normal activities (p=0.001) were significantly faster than after conventional haemorrhoidectomy. However, the overall incidence of complications reported was not significantly different (p=0.056). CONCLUSIONS: LigaSure is an effective instrument for haemorrhoidectomy which results in less blood loss, quicker wound healing and earlier return to work.


Assuntos
Procedimentos Cirúrgicos do Sistema Digestório/métodos , Hemorroidas/cirurgia , Hemostasia Cirúrgica/métodos , Procedimentos Cirúrgicos Vasculares/métodos , Perda Sanguínea Cirúrgica/estatística & dados numéricos , Humanos , Tempo de Internação , Medição da Dor , Complicações Pós-Operatórias/epidemiologia , Ensaios Clínicos Controlados Aleatórios como Assunto , Resultado do Tratamento
11.
Br J Dermatol ; 159(3): 661-8, 2008 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-18616767

RESUMO

BACKGROUND: Skin cancer is an increasing problem in fair-skinned populations worldwide. It is important that doctors are able to diagnose skin lesions accurately. OBJECTIVES: To compare the clinical with the histological diagnosis of excised skin lesions from a set of epidemiological data. We analysed diagnostic accuracy stratified by histological subtype and body site and examined the histological nature of misclassified diagnosis. METHODS: All excised and histologically confirmed skin cancers in Townsville/Thuringowa, Australia from December 1996 to October 1999 were recorded. Positive predictive values (PPVs) and sensitivities were calculated for the clinical diagnoses and stratified by histological subtype and body site. RESULTS: Skin excisions in 8694 patients were examined. PPVs for the clinical diagnoses were: basal cell carcinoma (BCC) 72.7%; squamous cell carcinoma (SCC) 49.4%; cutaneous melanoma (CM) 33.3%. Sensitivities for the clinical diagnosis were: BCC 63.9%; SCC 41.1%; CM 33.8%. For BCC, PPVs and sensitivities were higher for the trunk, the shoulders and the face and lower for the extremities. The reverse pattern was seen for SCCs. CONCLUSIONS: Diagnostic accuracy was highest for BCC, the most prevalent lesion. Most excisions were correctly diagnosed or resulted in the removal of malignant lesions. With nonmelanocytic lesions, doctors tended to misclassify benign lesions as malignant, but were less likely to do the reverse. Although a small number of clinically diagnosed common naevi subsequently proved to be melanoma (6.3%), a higher proportion of all melanomas had been classified as common naevi (20.9%). Accuracy of diagnosis was dependent on body site.


Assuntos
Competência Clínica , Dermatologia , Medicina de Família e Comunidade , Patologia Clínica/normas , Dermatopatias/diagnóstico , Adulto , Idoso , Austrália , Carcinoma Basocelular/diagnóstico , Carcinoma Basocelular/patologia , Carcinoma de Células Escamosas/diagnóstico , Carcinoma de Células Escamosas/patologia , Reações Falso-Negativas , Reações Falso-Positivas , Feminino , Humanos , Masculino , Melanoma/diagnóstico , Melanoma/patologia , Pessoa de Meia-Idade , Nevo/diagnóstico , Nevo/patologia , Nevo Pigmentado/diagnóstico , Nevo Pigmentado/patologia , Valor Preditivo dos Testes , Dermatopatias/patologia , Neoplasias Cutâneas/diagnóstico , Neoplasias Cutâneas/patologia
12.
Tech Coloproctol ; 11(2): 135-43, 2007 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-17510742

RESUMO

AIMS: This review compares the most popular techniques in managing the wounds after excisional haemorrhoidectomy, which are either to lay the wounds open or to close them. METHODS: Randomized controlled trials were identified from the major electronic databases using the search terms "hemorrhoid*" and "haemorrhoid*." Duration of operation, pain, length of hospital stay, time off work, time for wound healing, patient satisfaction, continence, manometry findings and complications were assessed. Quantitative meta-analysis was performed as appropriate or possible. RESULTS: Six trials including 686 patients met the inclusion criteria. The median follow-up time ranged from 1.5 to 19.5 months. Quantitative meta-analysis showed that there was no significant difference in cure rates between the two techniques (relative risk, 1.4; 95% CI, 0.86 to 2.2; p=0.191). Open haemor-rhoidectomy was more quickly performed (weighted mean difference, 1.03 min; 95% CI, 0.51 to 1.54; p<0.001). Closed haemorrhoidectomy wounds showed faster healing (weighted mean difference, 1.2 weeks; 95% CI, 0.88 to 1.55; p<0.001). Hospital stay, maximum pain score, total and individual complication rates were not significantly different. CONCLUSIONS: Apart from faster wound healing after closed haemorrhoidectomy, open and closed techniques appeared equally effective and safe. However, there were only a few studies which presented information in different ways, and statistical heterogeneity was high.


Assuntos
Procedimentos Cirúrgicos do Sistema Digestório/métodos , Hemorroidas/cirurgia , Humanos , Tempo de Internação , Manometria , Ensaios Clínicos Controlados Aleatórios como Assunto , Resultado do Tratamento , Cicatrização
13.
Br J Dermatol ; 155(2): 401-7, 2006 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-16882181

RESUMO

BACKGROUND: Basal cell carcinoma (BCC) is the most common cancer worldwide in white-skinned populations. Recent studies suggest that BCC is not a single entity and that different histological subtypes show different clinical behaviour and might have different aetiology. OBJECTIVES: To provide information on the incidence of BCC by histopathological subtype and body site. METHODS: A case series of BCC from a prospective population-based register study collecting information on all excised and histologically confirmed skin cancers in Townsville, north Australia between 1997 and 1999. RESULTS: Age-standardized incidence rates for nodular BCC were 727.1 per 100 000 inhabitants per year for males and 411.8 for females, while rates for superficial BCC were 336.5 for males and 251.4 for females. Incidence rates for 'high risk' BCC were 261.3 for males, 146.5 for females with infiltrative, and 156.7 for males and 100.2 for females with micronodular types. Superficial BCC occurred at a younger age, particularly in female patients. For all histological subtypes and both genders relative tumour density was highest for the face, followed by the neck. An exception was superficial BCC in males, where the posterior trunk was second, followed by the neck. CONCLUSIONS: The study found a higher rate of superficial BCC than previous studies from less sun-exposed countries, and a more equal distribution of superficial BCC on face, trunk and limbs. These results seem to blur the difference between intermittent and continuous sun exposure as the causative environmental agents. The clinical implications of 'high risk' BCC rates are discussed.


Assuntos
Carcinoma Basocelular/patologia , Neoplasias Cutâneas/patologia , Adulto , Distribuição por Idade , Idoso , Carcinoma Basocelular/classificação , Carcinoma Basocelular/epidemiologia , Feminino , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Queensland/epidemiologia , Fatores Sexuais , Neoplasias Cutâneas/classificação , Neoplasias Cutâneas/epidemiologia
14.
Arch Dis Child Fetal Neonatal Ed ; 89(2): F131-5, 2004 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-14977896

RESUMO

OBJECTIVE: To test the hypothesis that the application of intravaginal prostaglandin E(2) gel before elective caesarean section (ECS) will induce a catecholamine surge in umbilical arterial blood. DESIGN: Randomised, double blind, placebo controlled trial. SETTING: A regional perinatal referral centre. PATIENTS: Mothers booked for ECS at or above 38 weeks gestation. INTERVENTIONS: Thirty six consenting mothers were randomly allocated to receive either 2 mg intravaginal prostaglandin E(2) gel (study group; n = 18) or an equal volume of K-Y jelly as a placebo (control group; n = 18) 60 minutes before the ECS. Computer generated random numbers contained in coded, sealed envelopes were used for allocation. The obstetric and neonatal teams were blinded to the randomisation status of enrolled mothers. MAIN OUTCOME MEASURES: Catecholamine concentrations in the umbilical arterial blood samples collected at delivery. RESULTS: The median (interquartile range) neonatal gestation and birth weight were 271 (269-274) days and 3605 (3072-3970) g for the study group and 271 (270-273) days and 3340 (3000-3622) g for the control group. Median (interquartile range) noradrenaline (norepinephrine) concentrations in the umbilical arterial blood were significantly higher in the study group than the control group (15.9 (9.8-28.92) v 4.6 (1.65-14.4) ng/l, p = 0.03). Adrenaline (epinephrine) concentrations did not differ significantly between the two groups (1.6 (< 0.5-3.1) v 1.4 (< 0.5-2.75) ng/l, p = 0.6). No treatment related complications occurred. CONCLUSION: A labour related catecholamine surge could be simulated by intravaginal prostaglandin E(2) gel.


Assuntos
Catecolaminas/sangue , Cesárea , Dinoprostona/uso terapêutico , Sangue Fetal/química , Administração Intravaginal , Adulto , Método Duplo-Cego , Procedimentos Cirúrgicos Eletivos , Epinefrina/sangue , Feminino , Humanos , Recém-Nascido , Norepinefrina/sangue , Estudos Prospectivos , Estatísticas não Paramétricas
15.
J Paediatr Child Health ; 37(2): 113-7, 2001 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-11328463

RESUMO

OBJECTIVES: To determine the knowledge of vacant country specialist positions, the main barriers to filling country specialist positions, the acceptance of hypothetical creative employment models and to gain understanding of what would it take for respondents to accept a country position. METHODOLOGY: Mailed self-report questionnaires to all 103 Queensland paediatricians and finishing paediatric trainees (response rate 93.1%) to explore reasons for the long-term vacancy of the Staff Paediatrician position at the Mount Isa Base Hospital, North-west Queensland, Australia. RESULTS: Of the respondents, 87.4% were aware of the vacant position. The lack of adequate locum cover for leave (97.8%), on-call load (92.2%), professional isolation (91.4%), and family commitments (91.4%) were identified as the four most frequently recognized recruitment barriers. Of the respondents, 30.2% said they could be attracted to such a position if they were guaranteed the ability to return to their present post in 2 years, 30.7% said they could be attracted to a rural exchange, and 73.1% suggested the position would be more attractive to new Fellows if at the end of a 2-year period they were guaranteed some Visiting Medical Officer sessions or a temporary Staff Paediatrician position at a tertiary centre. Significantly, fewer of the 30-39-years age group said available job opportunities for their spouse made it impossible for them to consider the advertised position, compared to older age groups (P = 0.003). In response to the question 'What would it take for you to consider such a position?', 22.6% answered a change in employment package, 22.6% a change in family commitments, 16.6% too subspecialized, and 7.1% could possibly consider a locum or exchange in the future. CONCLUSIONS: Specialist positions, such as the advertised position, are well known, but remain unfilled because they are considered unsustainable. However, the response to hypothetical creative employment models suggests this could be changed, provided specialist training (e.g. paediatric training) is kept general and the younger consultant is given consideration.


Assuntos
Atitude do Pessoal de Saúde , Escolha da Profissão , Pediatria , Área de Atuação Profissional , Serviços de Saúde Rural , Criança , Emprego , Humanos , Área Carente de Assistência Médica , Modelos Organizacionais , Seleção de Pessoal/métodos , Queensland , Serviços de Saúde Rural/organização & administração , Inquéritos e Questionários , Recursos Humanos
16.
J Paediatr Child Health ; 37(5): 441-5, 2001 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-11885706

RESUMO

OBJECTIVES: To assess awareness of sudden infant death syndrome (SIDS) and risk reducing recommendations in a sample of mothers in North Queensland, Australia, and to examine their infant care practices. METHOD: Interviews conducted with 195 women using a standardized questionnaire between October 1997 and January 1998. RESULTS: 191 questionnaires analyzed; 134 (70.2%) Caucasian and 57 (29.8%) indigenous women. Four women with previous SIDS experience were excluded from the analysis. Eight (4.2%) had never heard of SIDS. Twenty-nine (15.2%) had heard of SIDS and 154 (80.6%) had heard of SIDS and could list risk recommendations to reduce its incidence. Multivariate analysis identified ethnicity as the only significant predictor of maternal knowledge. Indigenous mothers knew less about SIDS: adjusted odds ratio (OR) = 5.4; 95% confidence interval (CI) = [2.1-14.0]. Avoidance of prone sleeping was the most frequently identified recommendation (n = 132), with no smoking in pregnancy (n = 48) and breastfeeding (n = 40) identified least frequently. There were 80.2% of mothers who put their infant in non-prone positions to sleep. Only 48 (25%) women identified smoking in pregnancy, and 93 (48.6%) smoking in the infant's environment as risk factors. Indigenous women were more likely to smoke in their pregnancy (P = 0.004), bed share with their infant (P = 0.0001), and have smokers in the home. CONCLUSION: There is a high level of awareness of SIDS and the main associated risk factor of infant prone sleeping, but the link between SIDS and smoking requires further emphasis. Future campaigns should ensure the SIDS message is delivered more effectively to the indigenous communities.


Assuntos
Comportamentos Relacionados com a Saúde , Conhecimentos, Atitudes e Prática em Saúde , Cuidado do Lactente/métodos , Mães/estatística & dados numéricos , Morte Súbita do Lactente/epidemiologia , Morte Súbita do Lactente/prevenção & controle , Adulto , Conscientização , Feminino , Comportamentos Relacionados com a Saúde/etnologia , Humanos , Lactente , Cuidado do Lactente/normas , Recém-Nascido , Razão de Chances , Gravidez , Queensland/epidemiologia , Fatores de Risco , Morte Súbita do Lactente/etnologia
18.
Cancer ; 89(6): 1269-78, 2000 Sep 15.
Artigo em Inglês | MEDLINE | ID: mdl-11002222

RESUMO

BACKGROUND: The objective of this study was to describe recent developments in cutaneous melanoma from the German speaking countries in Europe (Germany, Austria, and Switzerland) and from Queensland, Australia. METHODS: All incident invasive cutaneous melanoma cases recorded between 1986 and 1996 by the Queensland Melanoma Register and by the Central Malignant Melanoma Registry of the German Dermatological Society were included in the analysis. Weighted linear trend analyses were performed to assess significant changes over the years using yearly sample sizes as weights. RESULTS: In Central Europe, the median tumor thickness decreased from 1.2 mm in 1986 to 0.8 mm in 1996 (P < 0.001), whereas it varied insignificantly between 0.5 mm and 0.6 mm in Queensland. The percentage of patients with Clark Level II invasion increased significantly in Queensland (P < 0.001; 1996, 61.1%) and in Central Europe (P = 0.041; 1996, 24.5%). The percentage of superficial spreading melanomas rose in Central Europe (P = 0.043; 1996, 64.4%), whereas it decreased slightly in Queensland (P = 0.032; 1996, 75%). In Queensland and in Central Europe, younger people and women presented more frequently with thinner melanomas (

Assuntos
Melanoma/epidemiologia , Melanoma/patologia , Neoplasias Cutâneas/epidemiologia , Neoplasias Cutâneas/patologia , Adulto , Fatores Etários , Idoso , Áustria/epidemiologia , Divisão Celular/fisiologia , Epidemiologia/tendências , Feminino , Alemanha/epidemiologia , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Invasividade Neoplásica , Prognóstico , Queensland/epidemiologia , Fatores de Risco , Fatores Sexuais , Suíça/epidemiologia
19.
Prev Med ; 31(2 Pt 1): 134-9, 2000 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-10938213

RESUMO

BACKGROUND: There is mounting evidence that sun exposure is a cause of skin cancer. Therefore, the focus of skin cancer prevention is on sun protection. The present study investigated the use of sunscreens in a sample from the adult Central European population. METHODS: As part of a case-control study of cutaneous melanoma, a total of 498 controls with classical dermatological disorders were selected from hospitals in Central Europe. All people underwent whole-body skin examinations and were interviewed using a standardized questionnaire. RESULTS: Overall, 40.8% of the people never used sunscreen and of the 281 persons who used sunscreen, 41.5% applied it only once per sun bath. Persons who did not use sunscreen tended to be older (P<0.0001) and of male gender (P = 0.0004). Young people, women, and people who expressed a positive attitude to the sun spent more time in the sun and were more likely to apply sunscreens. People who worked almost always outdoors had a six times increased odds ratio of not using sunscreens (P<0.0001) compared to people who worked always indoors. CONCLUSIONS: Men, older people, and outdoor workers should be targeted in health education campaigns. On the other hand, people who apply sunscreen as a means of sun protection should be advised about adequate usage.


Assuntos
Atitude Frente a Saúde , Conhecimentos, Atitudes e Prática em Saúde , Dermatopatias/prevenção & controle , Dermatopatias/psicologia , Protetores Solares/uso terapêutico , Adulto , Idoso , Áustria , Exposição Ambiental/efeitos adversos , Exposição Ambiental/análise , Feminino , Alemanha , Educação em Saúde , Humanos , Masculino , Pessoa de Meia-Idade , Avaliação das Necessidades , Fatores de Risco , Luz Solar/efeitos adversos , Inquéritos e Questionários , Suíça
20.
Am J Epidemiol ; 151(1): 72-7, 2000 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-10625176

RESUMO

The number of melanocytic nevi is the strongest risk factor for cutaneous melanoma. As pigmented skin lesions are visible to everybody, the question has been raised about whether people can identify themselves as being at risk for melanoma through self-counting of moles. In 1991, a total of 513 central European melanoma patients and 498 controls were asked to count the total number of nevi and the number of atypical nevi on the whole body. Whole-body examination by dermatologists followed. Agreement was assessed on categorized nevus counts by means of ordinal kappa values and log-linear modeling. Study subjects significantly underestimated the total number of melanocytic nevi (p < 0.0001). Chance-corrected overall agreement was rather poor (kappa = 0.14), and the ability to detect many existing nevi was low. Agreement was higher for atypical melanocytic nevi counts (kappa = 0.37), and the sensitivity to detect more than one atypical nevus was 0.48. Self-assessment of the number of melanocytic nevi was difficult to perform accurately, and people severely underestimated the actual number. Despite these results, people should be encouraged to perform regular skin self-examination for early detection of melanoma.


Assuntos
Dermatologia/métodos , Nevo Pigmentado/diagnóstico , Autoexame/métodos , Neoplasias Cutâneas/diagnóstico , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Melanoma/diagnóstico , Pessoa de Meia-Idade , Reprodutibilidade dos Testes , Fatores de Risco , Sensibilidade e Especificidade
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