RESUMO
Fine needle aspiration biopsies of tumors can yield a variety of spindle cells derived from several types of neoplasms. Among these is a rare lesion known as a "spindle-cell carcinoma" or "pseudosarcoma," which may represent a transformation of a preexisting squamous-cell carcinoma that has been subjected to radiotherapy or solar damage. The cytologic, histologic and ultrastructural features of a case of metastatic spindle-cell carcinoma of the rib subjected to fine needle aspiration are presented, and other spindle-cell tumors that should be considered in the differential diagnosis are discussed.
Assuntos
Neoplasias Ósseas/diagnóstico , Carcinoma/diagnóstico , Biópsia por Agulha , Neoplasias Ósseas/patologia , Carcinoma/patologia , Diagnóstico Diferencial , Humanos , Masculino , Microscopia Eletrônica , Pessoa de Meia-Idade , Metástase Neoplásica , CostelasRESUMO
The results of fine needle aspiration biopsy of lymph nodes in 350 patients and the modified biopsy technique used at our institution are discussed. Of the 350 cases, 209 aspirates were categorized as cytologically malignant, 102 as benign, 30 as suspicious for malignancy, and 9 as unsatisfactory. Cervical lymph nodes were most commonly sampled (58%), and supra-clavicular nodes were most likely to be malignant (90%). The overall diagnostic accuracy achieved was 94%. One false-positive and 9 (2%) false-negative results were observed in the 350 cases. In 3% of the 30 cases diagnosed as suspicious for malignancy, follow-up open biopsy of the lymph nodes in question proved them benign. The advantages and limitations of the procedure are discussed, as well as some of the possible sources of error, particularly in the diagnosis of lymphomas.
Assuntos
Biópsia por Agulha , Citodiagnóstico , Linfonodos/patologia , Doenças Linfáticas/diagnóstico , Metástase Linfática/diagnóstico , Diagnóstico Diferencial , Erros de Diagnóstico , Feminino , Humanos , Metástase Linfática/patologia , Linfoma/diagnóstico , Linfoma/patologia , MasculinoRESUMO
Corpora amylacea in the central and peripheral nervous system are round, amorphous intracellular bodies which are frequently found in large numbers around the ventricles of elderly individuals. These bodies were recently identified in a cytologic preparation of ventricular fluid. Although they have no known diagnostic significance, their possible confusion with yeast forms makes recognition of these structures important.
