RESUMO
Incidence was studied of risk factors (RF) in 669 patients with stage I and II hypertensive disease (as per WHO classification). There has been developed a risk-factor HD module. The prevailing RFs among HD patients include meteorolability, hereditary predisposition, hyperlipidemia, blood hypercoagulation, surplus body mass, hypodynamia, mental/nervous overstrain, consumption of salt going up, smoking, hyperglycemia, alcoholic liquor abuse, with n = 485 (72.5%), 417 (62.3%), 360 (53.8%), 335 (50.1%), 324 (48.4%0), 218 (32.6%), 166 (24.8%), 144 (21.5%), 84 (12.6%), 39 (5.8%), 8 (1.2%) respectively. A pathogenetic relation was found between RFs and HD clinical pattern determined by the RFs number and aggressiveness. The "mutual aggravation" phenomenon has been disclosed, its main point being to the effect that if a HD patient has several RFs, these would create certain conditions for development of each of them through affecting each other in a negative way.
Assuntos
Hipertensão/epidemiologia , Adulto , Suscetibilidade a Doenças , Humanos , Incidência , Pessoa de Meia-Idade , Prevalência , Fatores de RiscoRESUMO
It was established that a course of exposures of the renal region of rats with spontaneous hypertension to the effect of low-frequency magnetic field influenced the central hemodynamic parameters significantly, which was displayed by reduction of total peripheral vascular resistance and normalization of the cardiac output.
Assuntos
Hemodinâmica , Hipertensão/terapia , Magnetismo , Animais , Hipertensão/fisiopatologia , Masculino , Ratos , Ratos Endogâmicos SHRRESUMO
Dalargin, a small regulatory peptide produced in the USSR was tested with respect to its effect on psychological indices in 80 patients with essential hypertension grades I and II. Endonasal Dalargin electrophoresis was applied in 50 patients and 30 were subjected to endonasal galvanization (the control group). Electrophoretically applied Dalargin was shown to accelerate the sensorimotor responses, improve memory, reduce the anxiety levels.
Assuntos
Transtornos de Ansiedade/tratamento farmacológico , Leucina Encefalina-2-Alanina/análogos & derivados , Encefalina Leucina/análogos & derivados , Hipertensão/psicologia , Iontoforese , Transtornos da Memória/tratamento farmacológico , Transtornos Neurocognitivos/tratamento farmacológico , Adulto , Transtornos de Ansiedade/etiologia , Encefalina Leucina/administração & dosagem , Feminino , Humanos , Masculino , Transtornos da Memória/etiologia , Pessoa de Meia-Idade , Transtornos Neurocognitivos/etiologia , Desempenho Psicomotor/efeitos dos fármacos , Desempenho Psicomotor/fisiologiaRESUMO
The effect of low-frequency magnetic field (MF) on systemic blood pressure has been studied in chronic experiments on 21 spontaneously hypertensive rats. The animals' kidney area was exposed to MF (induction value 30T). Direct blood pressure measurements have revealed an antihypertensive effect.
Assuntos
Pressão Sanguínea , Magnetismo , Ratos Endogâmicos SHR/fisiologia , Ratos Endogâmicos/fisiologia , Animais , Hipertensão/fisiopatologia , Hipertensão/terapia , Rim , Masculino , Ratos , Fatores de TempoRESUMO
The authors presented and discussed the results of the use of the natural and instrumental physical methods for therapy, prevention and rehabilitation of 280 patients with coronary heart disease (CHD) and 300 patients with arterial hypertension (AH). The efficacy of the optimized use of a number of physical factors (precardial and segmental massage, low frequency magnetic field) was shown in the CHD and AH patients by the short- and long-term follow-up results. The authors substantiated the appropriateness of expanding the concept "nonpharmacological" methods proceeding from its practical meaning at the present-day stage of CHD and AH control.