[Immunochemical determination of neurospecific beta 2-globulin in cerebrospinal fluid in mental disorders]. / Immunokhimicheskoe opredelenie neirospetsificheskogo beta 2-globulina v spinomozgovoi zhidkosti pri psikhicheskikh zabolevaniiakh.

Immunochemical identification of neurospecific beta 2-globulin (N beta G) in the cerebrospinal fluid (CSF) of mentally healthy subjects and mental patients showed its immunochemical identity in both group. A comparative immunochemical analysis revealed considerable differences in N beta G levels in the CSF in patients with neuropsychic diseases as compared with the control group. The content of N beta G was found to vary in different psychopathological syndromes. It is suggested that variations in N beta G levels in the CSF may be related to psychomotor activity.

[Physico-chemical characteristics of human neurospecific beta 2 globulin]. / Fiziko-khimicheskaia kharakteristika neirospetsificheskogo beta2-globulina cheloveka.

Neurospecific beta 2-globulin was found to be a protein with molecular mass 20,000 +/- 2,000 daltons, exhibiting electrophoretic mobility of beta 2-globulins (0.29 +/- 0,05). Contrary to the S-100 protein the globulin was readily precipitated by ammonium sulfate at 30-60% of saturation. No carbohydrate and lipid components were found in the globulin. The beta 2-globulin appears to be a typical polypeptide.