RESUMO
BACKGROUND: Isolated and predominant gastrointestinal presentation in coronavirus disease 2019 (COVID-19) is reported less often. With evolving evidence that gastrointestinal tract can be a portal of entry, multiplication, primary site of affliction and symptomatic manifestation, and source of infectivity through prolonged fecal shedding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2), it is essential that isolated gastrointestinal symptoms can also be a mode of presentation of this novel virus and illness. CASE DESCRIPTION: The index case is a 10-year-old female child who presented with acute onset abdominal pain. Emergency surgery showed extensive gangrenous small bowel. The small bowel had herniated into a transmesenteric defect near the mid-ileum and was obstructed. Reverse-transcription polymerase chain reaction for SARS-CoV2 sent as preoperative work-up turned positive. The histopathology showed platelet aggregate thrombus in the venules with patent adjacent arterioles. CONCLUSION: This is probably the first reported case of COVID-19-related bowel gangrene. HOW TO CITE THIS ARTICLE: Kenchappa Y, Hegde S, Kumar P, Lalitha AV, Bukelo M. Caught Off Guard with COVID-19 Bowel Gangrene: A Case Report. Indian J Crit Care Med 2020;24(12):1269-1271.
RESUMO
BACKGROUND: Acute lymphoblastic leukemia (ALL) is a malignant disease of as yet an unknown origin. Researchers in the past have studied the association between dermatoglyphic features in the hand and congenital diseases and diseases with genetic influences. OBJECTIVE: The present research is intended to study the association between acute lymphoblastic leukemia (ALL) and palmar dermatoglyphic characteristics to assess the value of dermatoglyphics as a screening tool to detect leukemia in high risk groups. METHODS: Case-control study conducted at the department of Pediatrics, KMC Attavara, a tertiary care teaching hospital of Kasturba Medical College, Mangalore (Manipal University), India during 2006. Twenty-four children suffering from acute lymphoblastic leukemia were included in the study. The dermatoglyhic features (ab- ridge count, atd, tda and dat angles) of their palm prints were compared with the age and sex matched controls. RESULTS: The present research indicates an association between dermatoglyphic features and ALL. The mean ab-ridge count, and the mean atd - angle were observed to be higher in cases while the mean tda - angle was found to be lower in cases than controls. CONCLUSIONS: The findings of the present research are suggestive of a possible trend and an association of dermatoglyphic features with children suffering from ALL. Similar studies can be useful in rare forensic case work where the association of dermatoglyphic features with certain diseases is to be explored.
