[Influence of TORCH-infections on the spermatogenesis of men].

The purpose of the given study was to reveal causal relations between infection of the urino-genital tract by intracellular parasites, the so-called TORCH-infections, and the decrease of spermatogenesis. For observation 182 men of reproductive age (from 22 to 38 years) with oligozoospermia and aspermia, without any complaints or clinical symptoms indicating existence of infections of urino-genital tracts, were selected. Out of those, 131 revealed oligozoospermia, i.e. the quantity of spermatozoons was no higher than 20 mln in 1 ml of ejaculate, and 51 revealed - aspermia. For examination of some TORCH infections, medical doctors in charge directed 44 oligozoospermia patients and 15 aspermia patients, who respectively constituted group I and group II. Examinations were carried out for Chlamydia trachomatis--(Ch.t), Herpes simplex virus--(HSV), Ureaplasma urealiticum--(U.u.), Cytomegalovirus--(CMV), and Mycoplasma hominis--(M.h.). In the group with oligozoospermia, cases of infections by Chlamydias (41.5%) and Herpes virus (51.3%) were frequent, but Ureaplasma (56,5%) was more frequent than any infections. Cytomegalovirus occurred in the least number of cases. Making any conclusions on the frequency of infections by M.h. is difficult due to the low number of examinations. Similar picture was observed in Group II as well. Following successful treatment of infections in Group I, 8 patients with Ch.t. and 8 patients with U.u. showed an improved spermogram after several months. Treatment of other infections did not yield tangible results. In Group II spermatogenesis remained without any changes.

[Alternative to donor organs--the method of cultivation from fragments of tissues of "new organs" in an organism of the recipient].

A method of "new liver" growing inside of the recipients' organism as an alternative of the donor organs is presented. Experiments were carried out on the 90 Wistar rats. Animals were divided into 3 equal groups. All of the animals were subjected to 40% hepatectomy. The liver fragments were harvested from resected lobe. The animals of the I group received liver fragments transplantation into the greater omentum pocket, animals of the II group--into the peritoneal cavity and animals of the III group--into the "Kakabadze Biocontainer". All animals were under the standard vivarium conditions and were sacrificed in the different time points. The maximal follow up period was 6 months. Performed investigations have shown that vascularized, denuded segment of small intestine is uncial site for the engraftment and future development of transplanted liver fragments.