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1.
Food Nutr Bull ; 31(2): 221-33, 2010 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-20707228

RESUMO

BACKGROUND: Anemia and micronutrient deficiencies are common among Indian schoolchildren. However, past studies have narrowly focused on only a few micronutrients and have not carefully evaluated the association between sociodemographic factors and nutritional status of schoolchildren. OBJECTIVE: To assess the nutritional status of schoolchildren in Himalayan villages of India and to determine the relationships between their nutritional status, intestinal helminth infection, and sociodemographic characteristics. METHODS: A random sample of 499 children 6 to 10 years of age from 20 public primary schools was selected. Household sociodemographic data and morbidity data on children were collected through interviews with their caretakers. Height and weight were measured, and venous blood was drawn for assessment of hemoglobin, serum ferritin, soluble transferrin receptor, retinol, zinc, folic acid, vitamin B12, and C-reactive protein. Stool samples were analyzed for parasitic infections. Results. Underweight, stunting, and wasting were present in 60.9%, 56.1%, and 12.2% of schoolchildren, respectively. Anemia, iron-deficiency anemia, and low serum concentrations of ferritin, zinc, retinol, folate, and vitamin B12 were found in 36.7%, 10.2%, 24.1%, 57.1%, 56.1%, 67.9%, and 17.4% of the children, respectively. One-fifth of the children had intestinal parasites. Being underweight was associated with lower household wealth (p < .05). Helminth infection was associated with stunting, anemia, and low serum retinol (p < .05). Living at higher altitude was associated with low serum levels of ferritin, retinol, and vitamin B12. There were no associations between any sociodemographic variables and serum zinc orfolate. CONCLUSIONS: Growth impairment and micronutrient deficiencies are prevalent among schoolchildren in Himalayan villages of India.


Assuntos
Transtornos da Nutrição Infantil/epidemiologia , Etnicidade/estatística & dados numéricos , Estado Nutricional , Altitude , Anemia/sangue , Anemia/epidemiologia , Índice de Massa Corporal , Criança , Transtornos da Nutrição Infantil/sangue , Estudos Transversais , Fezes/parasitologia , Feminino , Transtornos do Crescimento/sangue , Transtornos do Crescimento/epidemiologia , Helmintíase/sangue , Helmintíase/epidemiologia , Humanos , Índia/epidemiologia , Enteropatias Parasitárias/sangue , Enteropatias Parasitárias/epidemiologia , Masculino , Micronutrientes/sangue , Micronutrientes/deficiência , Morbidade , População Rural , Fatores Socioeconômicos
2.
J Nutr ; 140(6): 1146-54, 2010 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-20410083

RESUMO

Anemia and micronutrient deficiencies are common among Indian schoolchildren. We assessed the effectiveness of micronutrient fortification of meals cooked and fortified at school on anemia and micronutrient status of schoolchildren in Himalayan villages of India. In this placebo-controlled, cluster-randomized study, 499 schoolchildren (6-10 y) received either multiple micronutrients (treatment group) or placebo (control group) as part of school meals (6 d/wk) for 8 mo. Both groups were dewormed at the beginning of the study. The micronutrient premix provided 10 mg iron, 375 microg vitamin A, 4.2 mg zinc, 225 microg folic acid, and 1.35 microg vitamin B-12 for each child per day (approximately 75% recommended dietary allowance). Blood samples drawn before and after the intervention were analyzed for hemoglobin, ferritin, retinol, zinc, folate, and vitamin B-12. Baseline prevalence of anemia (37%), iron deficiency anemia (10%), low serum ferritin (24%), retinol (56%), zinc (74%), folate (68%), and vitamin B-12 (17%) did not differ between groups. Postintervention, fewer in the treatment group had lower serum retinol [odds ratio (OR) (95% CI): 0.57 (0.33-0.97)] and folate [OR (95% CI): 0.47 (0.26-0.84)] than the control group. The serum vitamin B-12 concentration decreased in both groups, but the magnitude of change was less in the treatment than in the control group (P < 0.05). Total body iron (TBI) increased in both groups; however, the change was greater in the treatment than in the control group (P < 0.05). Micronutrient fortification of school meals by trained school personnel was effective in improving vitamin A, folate, and TBI status while also reducing the magnitude of a decrease in vitamin B-12 status.


Assuntos
Serviços de Alimentação , Micronutrientes/administração & dosagem , Micronutrientes/farmacologia , Instituições Acadêmicas , Anemia/prevenção & controle , Antropometria , Suplementos Nutricionais , Feminino , Ácido Fólico/administração & dosagem , Ácido Fólico/sangue , Análise de Alimentos , Alimentos Fortificados , Humanos , Índia , Ferro/administração & dosagem , Ferro/sangue , Modelos Logísticos , Masculino , Análise Multivariada , Vitamina A/administração & dosagem , Vitamina A/sangue
3.
Indian Pediatr ; 44(11): 823-9, 2007 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-18057478

RESUMO

OBJECTIVE: To assess the efficacy of micronutrient fortified sugar candies in improving the iron and vitamin A status in children aged 3 to 6 years. DESIGN: Triple blind randomized controlled trial. SETTINGS: Anganwadis and preparatory schools in rural Haryana. METHODS: 410 children were randomized in four groups. One group received full dose candy (vitamin A 1000 IU and 14 mg elemental iron) daily, the second group received full dose candy for 3 days a week, the third group received half dose candy (vitamin A 500 IU and 7 mg elemental iron) daily and the fourth received placebo. The candies were provided to children under supervision of field workers. Hemoglobin, S. ferritin, S. retinol and S. retinol binding protein levels were estimated at baseline and after 13 weeks of intervention. RESULTS: The increase in hemoglobin was least in the placebo group (0.3 g/dL) as compared to the two full dose groups (1.15-1.18 g/dL, P < 0.001). Among anemic children, the increase in hemoglobin was about 2 g/dL in the full dose group and 0.7 g/dL in the placebo group (P < 0.001). S. ferritin levels increased significantly only in the full dose daily group (p < 0.05). The prevalence of anemia decreased from around 50% at baseline to 9.6% in the full dose daily group (p < 0.01). Based on the S. retinol levels, the study area was not vitamin A deficient and the intervention did not result in a significant improvement in the vitamin A status of the children. CONCLUSION: Micronutrient fortified candies were effective in improving the hemoglobin level and decreasing anemia prevalence. It could serve as a suitable vehicle for micronutrient supplementation in children and other target groups.


Assuntos
Doces , Ferritinas/sangue , Alimentos Fortificados , Micronutrientes/administração & dosagem , Vitamina A/sangue , Criança , Pré-Escolar , Método Duplo-Cego , Feminino , Hemoglobinas/análise , Humanos , Masculino , População Rural
4.
Artigo em Inglês | MEDLINE | ID: mdl-17664899

RESUMO

Malnutrition is a major problem among children especially in the developing world. In most developing countries children show growth faltering between 6 and 24 months of age due to inadequate complementary feeding. Complementary foods are transitional foods given in addition to breast milk, following exclusive breastfeeding during the first 6 months, to meet the full nutritional requirements of the infant. Strategies to improve the availability of and accessibility to low cost complementary foods can play an important role in improving the nutritional status of infants and young children. Cereals constitute the most suitable vehicle for delivering micronutrients to an at-risk population because of their widespread consumption, stability and versatility. To reduce the vulnerability to the health impacts of micronutrient deficiencies, several developed and developing countries have adopted various innovative, cost-effective strategies to fortify cereal-based complementary foods and to reach children through public programs. This article reviews cereal fortification programs in developing countries, with special reference to low cost fortified complementary foods, and emphasizes the need for public-private-civic sector initiatives to improve the health and wellbeing of people around the world.


Assuntos
Grão Comestível/química , Alimentos Fortificados , Fenômenos Fisiológicos da Nutrição do Lactente/fisiologia , Necessidades Nutricionais , Estado Nutricional , Países em Desenvolvimento , Feminino , Humanos , Lactente , Masculino , Desmame
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