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1.
Sud Med Ekspert ; 53(3): 14-6, 2010.
Artigo em Russo | MEDLINE | ID: mdl-20734783

RESUMO

The authors present results of comparative morphological studies of changes in the liver after intoxication with alcohol-containing liquids in human and following subacute treatment of animals with ethyl and propyl alcohols, ethylene glycol and their mixtures. It was shown that poisoning caused by individual chemical substances and their mixtures induced significantly different changes in the liver of animals. The mixtures produced much more serious toxic lesions in the parenchymal tissue than individual spirits (including development of necrotization foci) and contributed to enhanced mortality of experimental animals. The morphological picture of the liver in human subjects poisoned by a mixture of alcohols resembled that after intoxication with carbon tetrachloride and was consistent with the changes in people who had died during episodes of mass poisoning with surrogate alcoholic beverages and alcohol-containing liquids.


Assuntos
1-Propanol/intoxicação , Bebidas Alcoólicas/efeitos adversos , Depressores do Sistema Nervoso Central/efeitos adversos , Etanol/efeitos adversos , Etilenoglicol/intoxicação , Fígado/patologia , Animais , Modelos Animais de Doenças , Feminino , Humanos , Masculino , Necrose , Ratos
2.
Gig Sanit ; (1): 70-2, 2009.
Artigo em Russo | MEDLINE | ID: mdl-19358361

RESUMO

The paper presents the data on the impact of the most possible concentrations of fluogermanate (GeF4) in the air of a working area with a pencil-beam irritant acting the respiratory organs and those obtained from chronic experiments. The most possible concentration is 0.2 mg/m3 (Class II hazard).


Assuntos
Poluentes Ocupacionais do Ar/química , Fluoretos/análise , Germânio/análise , Higiene/normas , Nomogramas , Animais , Humanos , Ratos
3.
Gig Sanit ; (1): 62-4, 2005.
Artigo em Russo | MEDLINE | ID: mdl-15751307

RESUMO

The paper presents the results of investigations on the hygienic standardization of the levels of selenium hexafluoride (SeF6) in the air of a working area. It also analyzes the data on the effects of SeF6 inhalation on laboratory animals, by applying morphological, physiological, hematological, and biochemical studies. The studies have yielded the basic parameters of inhalation toxicity and established the threshold of the irritant action of the substance, developed and approved its maximally acceptable concentration (0.2 mg/m3, gas + vapors) and a procedure for photometric determination of SeF6 in the air of a working area.


Assuntos
Poluentes Ocupacionais do Ar/análise , Poluentes Ocupacionais do Ar/toxicidade , Fluoretos/análise , Fluoretos/toxicidade , Compostos de Selênio/análise , Compostos de Selênio/toxicidade , Animais , Cobaias , Humanos , Inalação , Concentração Máxima Permitida , Modelos Teóricos , Fotometria , Coelhos , Ratos , Fatores de Tempo
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