[Test for determination of attention in patients with sleep apnea syndrome]. / Test pentru determinarea atentiei la pacientii cu sindrom de apnee în somn.

To investigate the daytime sleepiness in patients with sleep apnea syndrome, we used a test for measurement of sustained attention. The present study was performed on 65 participants: 10 healthy non-snoring volunteers, 25 snoring volunteers and 30 patients with symptoms of sleep apnea. The error rate (percentage of incorrect responses) appears to be most suitable for the evaluation of the test. The difference between the habitual snorers and the healthy non-snoring volunteers was statistically significant. At the apneic patients, there are significant differences in age, sex, and body mass index; attention decreases significantly in the last 10 minutes of the test. The attention test can be helpful for the measurement of daytime sleepiness in apneic patients.

Experimental studies on human bronchial smooth muscle in vitro.

The aim of this study was the investigation of bronchial reactivity in human bronchial smooth muscle in vitro. In fact, the study has two purposes: to achieve the best methods of research on human bronchial strips reactivity in vitro; to reveal the effect of acetylcholine and histamine on bronchial smooth muscle; The contractile effect of acetylcholine appears at 10(-6) M in the organ-bath; the maximal acetylcholine contraction was obtained at 10(-3) M in the organ-bath. Histamine induced a maximal contraction at 10(-3) M, but a concentration of 10(-3) M in the organ bath had no effect.