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1.
Radiat Prot Dosimetry ; 178(4): 382-404, 2018 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-28981844

RESUMO

Biological and physical retrospective dosimetry are recognised as key techniques to provide individual estimates of dose following unplanned exposures to ionising radiation. Whilst there has been a relatively large amount of recent development in the biological and physical procedures, development of statistical analysis techniques has failed to keep pace. The aim of this paper is to review the current state of the art in uncertainty analysis techniques across the 'EURADOS Working Group 10-Retrospective dosimetry' members, to give concrete examples of implementation of the techniques recommended in the international standards, and to further promote the use of Monte Carlo techniques to support characterisation of uncertainties. It is concluded that sufficient techniques are available and in use by most laboratories for acute, whole body exposures to highly penetrating radiation, but further work will be required to ensure that statistical analysis is always wholly sufficient for the more complex exposure scenarios.


Assuntos
Doses de Radiação , Radiometria/métodos , Incerteza , Carga Corporal (Radioterapia) , Europa (Continente) , Humanos , Monitoramento de Radiação , Radiação Ionizante , Medição de Risco/métodos
2.
Int J Radiat Biol ; 93(1): 136-141, 2017 01.
Artigo em Inglês | MEDLINE | ID: mdl-27557790

RESUMO

PURPOSE: To identify and assess, among the participants in the RENEB (Realizing the European Network of Biodosimetry) project, the emergency preparedness, response capabilities and resources that can be deployed in the event of a radiological or nuclear accident/incident affecting a large number of individuals. These capabilities include available biodosimetry techniques, infrastructure, human resources (existing trained staff), financial and organizational resources (including the role of national contact points and their articulation with other stakeholders in emergency response) as well as robust quality control/assurance systems. MATERIALS AND METHODS: A survey was prepared and sent to the RENEB partners in order to acquire information about the existing, operational techniques and infrastructure in the laboratories of the different RENEB countries and to assess the capacity of response in the event of radiological or nuclear accident involving mass casualties. The survey focused on several main areas: laboratory's general information, country and staff involved in biological and physical dosimetry; retrospective assays used, the number of assays available per laboratory and other information related to biodosimetry and emergency preparedness. Following technical intercomparisons amongst RENEB members, an update of the survey was performed one year later concerning the staff and the available assays. CONCLUSIONS: The analysis of RENEB questionnaires allowed a detailed assessment of existing capacity of the RENEB network to respond to nuclear and radiological emergencies. This highlighted the key importance of international cooperation in order to guarantee an effective and timely response in the event of radiological or nuclear accidents involving a considerable number of casualties. The deployment of the scientific and technical capabilities existing within the RENEB network members seems mandatory, to help other countries with less or no capacity for biological or physical dosimetry, or countries overwhelmed in case of a radiological or nuclear accident involving a large number of individuals.


Assuntos
Pesquisa Biomédica/organização & administração , Planejamento em Desastres/organização & administração , Monitoramento de Radiação/métodos , Proteção Radiológica/métodos , Liberação Nociva de Radioativos , Gestão da Segurança/organização & administração , Europa (Continente) , Modelos Organizacionais , Radiobiologia/organização & administração
3.
Int J Radiat Biol ; 93(1): 75-80, 2017 01.
Artigo em Inglês | MEDLINE | ID: mdl-27559844

RESUMO

PURPOSE: The RENEB accident exercise was carried out in order to train the RENEB participants in coordinating and managing potentially large data sets that would be generated in case of a major radiological event. MATERIALS AND METHODS: Each participant was offered the possibility to activate the network by sending an alerting email about a simulated radiation emergency. The same participant had to collect, compile and report capacity, triage categorization and exposure scenario results obtained from all other participants. The exercise was performed over 27 weeks and involved the network consisting of 28 institutes: 21 RENEB members, four candidates and three non-RENEB partners. RESULTS: The duration of a single exercise never exceeded 10 days, while the response from the assisting laboratories never came later than within half a day. During each week of the exercise, around 4500 samples were reported by all service laboratories (SL) to be examined and 54 scenarios were coherently estimated by all laboratories (the standard deviation from the mean of all SL answers for a given scenario category and a set of data was not larger than 3 patient codes). CONCLUSIONS: Each participant received training in both the role of a reference laboratory (activating the network) and of a service laboratory (responding to an activation request). The procedures in the case of radiological event were successfully established and tested.


Assuntos
Planejamento em Desastres/organização & administração , Monitoramento de Radiação/métodos , Liberação Nociva de Radioativos , Radiobiologia/educação , Gestão da Segurança/organização & administração , Triagem/organização & administração , Europa (Continente)
4.
Int J Radiat Biol ; 93(1): 65-74, 2017 01.
Artigo em Inglês | MEDLINE | ID: mdl-27584947

RESUMO

PURPOSE: In the EC-funded project RENEB (Realizing the European Network in Biodosimetry), physical methods applied to fortuitous dosimetric materials are used to complement biological dosimetry, to increase dose assessment capacity for large-scale radiation/nuclear accidents. This paper describes the work performed to implement Optically Stimulated Luminescence (OSL) and Electron Paramagnetic Resonance (EPR) dosimetry techniques. MATERIALS AND METHODS: OSL is applied to electronic components and EPR to touch-screen glass from mobile phones. To implement these new approaches, several blind tests and inter-laboratory comparisons (ILC) were organized for each assay. RESULTS: OSL systems have shown good performances. EPR systems also show good performance in controlled conditions, but ILC have also demonstrated that post-irradiation exposure to sunlight increases the complexity of the EPR signal analysis. CONCLUSIONS: Physically-based dosimetry techniques present high capacity, new possibilities for accident dosimetry, especially in the case of large-scale events. Some of the techniques applied can be considered as operational (e.g. OSL on Surface Mounting Devices [SMD]) and provide a large increase of measurement capacity for existing networks. Other techniques and devices currently undergoing validation or development in Europe could lead to considerable increases in the capacity of the RENEB accident dosimetry network.


Assuntos
Bioensaio/instrumentação , Espectroscopia de Ressonância de Spin Eletrônica/instrumentação , Exposição à Radiação/análise , Dosimetria Termoluminescente/instrumentação , Triagem/métodos , Bioensaio/normas , Espectroscopia de Ressonância de Spin Eletrônica/normas , Desenho de Equipamento , Análise de Falha de Equipamento , Europa (Continente) , Humanos , Linfócitos/efeitos da radiação , Garantia da Qualidade dos Cuidados de Saúde , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Integração de Sistemas , Dosimetria Termoluminescente/normas , Triagem/normas
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