Quantum measurement enables single biomarker sensitivity in flow cytometry.

We present the first unambiguous experimental method enabling single-fluorophore sensitivity in a flow cytometer using quantum properties of single-photon emitters. We use a quantum measurement based on the second-order coherence function to prove that the optical signal is produced by individual biomarkers traversing the interrogation volume of the flow cytometer from the first principles. This observation enables the use of the quantum toolbox for rapid detection, enumeration, and sorting of single fluorophores in large cell populations as well as a 'photons-to-moles' calibration of this measurement modality.

Practical quantum-enhanced receivers for classical communication.

Communication is an integral part of human life. Today, optical pulses are the preferred information carriers for long-distance communication. The exponential growth in data leads to a "capacity crunch" in the underlying physical systems. One of the possible methods to deter the exponential growth of physical resources for communication is to use quantum, rather than classical measurement at the receiver. Quantum measurement improves the energy efficiency of optical communication protocols by enabling discrimination of optical coherent states with the discrimination error rate below the shot-noise limit. In this review article, the authors focus on quantum receivers that can be practically implemented at the current state of technology, first and foremost displacement-based receivers. The authors present the experimentalist view on the progress in quantum-enhanced receivers and discuss their potential.

Experimental demonstration of the near-quantum optimal receiver.

We implement the cyclic quantum receiver based on the theoretical proposal of Roy Bondurant and demonstrate experimentally below the shot-noise limit (SNL) discrimination of quadrature phase-shift keying signals (PSK). We also experimentally test the receiver generalized for longer communication alphabet lengths and coherent frequency shift keying (CFSK) encoding. Using off-the-shelf components, we obtain state discrimination error rates that are 3 dB and 4.6 dB below the SNLs of ideal classical receivers for quadrature PSK and CFSK encodings, respectively. The receiver unconditionally surpasses the SNL for M=8 PSK and CFSK. This receiver can be used for the simple and robust practical implementation of quantum-enhanced optical communication.