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Sud Med Ekspert ; 63(2): 32-40, 2020.
Artigo em Russo | MEDLINE | ID: mdl-32297497

RESUMO

Aim of this study was to develop a fast screening method for identification of illegal drugs including new psychoactive substances and their metabolites in human urine by means of liquid chromatography mass-spectrometry HPLC-MS/MS screening method for identification of 138 psychoactive substances in urine was established, validated and tested. High-resolution mass-spectrometry was used for confirmation of the developed approach. The developed method was tested on 50 positive urine samples containing the target compounds, which proved reliability and accuracy of the established screening method.


Assuntos
Cromatografia Líquida de Alta Pressão , Drogas Ilícitas/urina , Detecção do Abuso de Substâncias/métodos , Espectrometria de Massas em Tandem , Humanos , Reprodutibilidade dos Testes
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