Arthrodesis of the wrist with bone autograft and Hoffmann external fixation.

We report a series of 29 cases of wrist arthrodesis using a radiometacarpal half-frame or triangular Hoffmann configuration, bone autograft, and relocation of a retinacular rectangular flap under the extensor tendons to prevent adhesions. No splint or plaster cast has been used. Early active motion of the fingers was encouraged. The average duration of follow-up was 4 years. Bone healing was obtained in 27 patients after 104 days on average. All patients regained full finger movements and rotation of the forearm. Nine patients were reassessed on average 7.2 years after the arthrodesis: the VAS for pain at rest was 2.4/10, the DASH score 33/100, the grip strength 75% of the contralateral side on average.

Risk factors and impact of orthopaedic monitoring on the outcome of avascular necrosis of the femoral head in adults with sickle cell disease: 215 patients case study with control group.

INTRODUCTION: Sickle cell disease is a public health problem. The WHO has recommended that global management be implemented to reduce mortality and morbidity. Since no comprehensive care programme for bone and joint complications exists, the Caribbean Sickle Cell Disease Center added orthopaedic consultation to screen for and monitor these complications in 1992. HYPOTHESIS: Comprehensive medical and surgical care of patients with sickle cell disease will reduce the complications and disability associated with this disease. POPULATIONS AND METHODS: Two populations were compared to evaluate the impact of comprehensive disease management on the occurrence of avascular necrosis (AVN) of the femoral head (femoral head AVN). The case-control series, [E-1994], included 115 patients (58 SS and 57 S) without orthopaedic monitoring and was evaluated retrospectively. The other patient series, [E-2008], included 215 patients (94 SS and 121 SC) with systematic orthopaedic care and was followed prospectively. Age, gender, duration of follow-up, haemoglobin levels, genotype, pain before treatment, associated humerus AVN and leg ulcers were analysed. RESULTS: Femoral head AVN occurred in young adult patients (35.3 ± 4 years for [E-1994] and 29 ± 3.4 years for [E-2008]). Only elevated haemoglobin levels were associated with the occurrence of femoral head AVN, which suggests that increased blood viscosity contributes to the condition ([E-1994], P<0.0001; [E-2008], P=0.001). Treatment in [E-2008] patients reduced the number of femoral head AVN cases from 36.5% in [E-1994] to 14.4% in [E-2008] (P<0.0001). DISCUSSION: The prevention and management of femoral head AVN must include medical treatment of the disease to reduce the occurrence of painful vaso-occlusive crises, which are known to trigger femoral head AVN. The effectiveness of this programme hinged on identifying risk factors and using simple approaches (hydration, pain medication, rest and crutches) to manage painful joint crises before femoral head AVN appeared. These approaches could be implemented in disadvantaged countries where sickle cell disease is prevalent. CONCLUSION: By knowing the risk factors, symptomatic patients who are at risk for femoral head AVN can be identified and additional evaluations can be performed early on in cases of hip pain.

[The Department of Orthopaedics and Traumatology of the University Clinics of Brussels, Erasme Hospital]. / Le Service d'Orthopédie-Traumatologie des Cliniques Universitaires de Bruxelles, hôpital Erasme.

On the occasion of the thirty years since its inauguration, the Department of Orthopaedics and Traumatology of the University Hospital Erasme reviews the milestones of its development. Various original new techniques have been implemented: monitoring of implants using strain gauges, external fixation of the limbs, external minifixation, miniinvasive anterior approach in hip arthroplasty, knee ligamentoplasties, orthopaedic microsurgery and composite tissue allotransplantation. The care of aged patients takes place in close collaboration with the Department of Geriatrics. Two new clinical units have been created, the Unit of Hand and Peripheral Nerve Surgery, and the Centre for Sports. The Department has organized an efficient Bone Bank. The new day care hospital improves the possibilities of ambulatory surgery. The article details as well the activities of teaching and research of the members of the Department.

[The Orthopaedic and Traumatology Research Laboratory]. / Le Laboratoire de Recherche en Orthopédie Traumatologie - LROT.

The history of the Orthopaedics and Traumatology Research Laboratory (LROT) is summarized during the last thirty years. The approach, initially focused on bone biomechanics and strength of materials, underwent a rapid diversification as expressed by the list of research topics: monitoring of bone healing; bone strains measurements for different level of activities including microgravity and prevention of disuse osteoporosis; biological effects of electromagnetic fields; evolution of the viscoelastic properties of the callus during bone healing; improvement of the osteoinductive properties of bone substitutes produced by the Tissues Bank of the University Hospital Erasme; Kashin-Beck disease; SICOT telediagnostic, and biomechanics of threaded implants. Those topics, event the most fundamental ones, have immediate significant clinical applications allowing a decrease of the morbidity and an acceleration of the rehabilitation of the patients. The results show the need of multidisciplinary collaborations coordinated around one autonomous laboratory, able to handle specific protocols requiring a dedicate environment.

[External fixation at the wrist and hand]. / Fixation externe au poignet et à la main.

Distraction radio-metacarpal external fixation is an excellent technique for the osteosynthesis of distal radius fractures, in particular of comminuted articular fractures. The alternative is the locked palmar plate, a more demanding technique. The published literature does not allow concluding if one method is better than the other. The other main possible indications of external fixation at the wrist are comminuted fractures of the base of the thumb metacarpal, distal radius osteotomies, and wrist arthrodeses. At the hand, external minifixation is an excellent technique of osteosynthesis. Stable bone fixation is obtained, allowing early active mobilization of the fingers. The technique is especially indicated to treat open lesions or to perform lengthening, but we use also external minifixation to treat closed fractures, to perform arthrodesis or to cure non-unions, and to maintain the length of the thumb after trapeziectomy for osteoarthrosis.

Treatment of sickle cell disease's hip necrosis by core decompression: a prospective case-control study.

INTRODUCTION: The young age of patients, total arthroplasties complications risks, and implant costs justify evaluation of the results of core decompression in the treatment of sickle-cell disease avascular necrosis of the femoral head (ONFH). HYPOTHESIS: In sickle-cell disease necrosis, core decompression offers good relief from pain and delays the use of total arthroplasty in comparison to a conservatively treated control group by a simple non-weight bearing protocol. MATERIALS AND METHODS: From 1994 to 2008, among 215 drepanocytic adults, 42 patients (22 genotype SS, 20 genotype SC; 15 men, 27 women) presented symptomatic ONFH. We report the data from a prospective study of two patients' groups: a non-operated group (16 patients aged 36.5+/-6.5 years, 23 hips) and an operated group (26 patients aged 30.3+/-2.8 years, 42 hips). The results were considered on the basis of change in clinical status according to the numeric evaluation of pain scale, the functional score of Merle d'Aubigné-Postel (MAP), the radiological progression of lesions, and the time delay to total arthroplasty. RESULTS: Twenty-three hips were conservatively treated by discharge (a pair of canes). After a follow-up period of 13.4+/-0.5 years, no pain improvement was noted (p=0.76), and MAP score was unchanged (p=0.27). Out of 23 hips managed by discharge, 9 stage IV hips (degenerative arthritis, 39.1%) underwent arthroplasty after an average delay of 2.6+/-2.4 years. Forty-two hips were treated by core decompression. The duration of follow-up was 11.3+/-1.8 years. Postoperatively, pain reduction and MAP score improvement were significant in 39 out of 42 hips (93%, p<0.0001). Twenty-nine out of these 42 hips had a favorable evolution. Ten hips (23.8%) progressed to total arthroplasty, after a period of 7.4+/-2.7 years, longer than the one of the non-operated group (p=0.0007). By comparing the two groups (operated and non-operated), the benefit of core decompression appeared very significant (p<0.0001). In addition to allocating patients osteonecrosis stages, the Koo and Kim Index estimated the severity and evolution of necrotic lesions in both groups. It indicated decline in the non-operated group (p=0.002) and improvement for operated patients (p=0.0002). DISCUSSION: Core decompression had a favorable clinical and radiological outcome superior to surgical abstention. Stages I and II ONFH remained stable after drilling, necessitating no arthroplasty (considered as a failure of drilling). The Koo and Kim Index above 30 degrees in the non-operated group was a significant indicator of lesions degradation (p=0.002). In addition to the indolence obtained by core decompression, the benefit of drilling was manifested by the prolonging the adjournment before arthroplasty end-point. It was respectively 7.4+/-2.7 years in the operated group versus 2.6+/-2.4 years in the non-operated group (difference of 4.8 years, p<0.01). CONCLUSION: The technique of core decompression remains a valid option place in the treatment sickle-cell disease avascular necrosis of the femoral head (ONFH). It may be especially recommended in under-equipped regions where drepanocytosis and its osteo-articular complications are frequent. LEVEL OF EVIDENCE: Level III case-control therapeutic study.

Sickle-cell hip necrosis and intraosseous pressure.

INTRODUCTION: Osteonecrosis of the femoral head (ONFH) is a frequent complication of sickle-cell disease. Numerous studies have demonstrated increased intraosseous pressure (IOP) in idiopathic necrosis and necrosis secondary to corticotherapy or alcohol poisoning. Several reports have testified to the clinical interest of decompression by drilling which, when performed in the early course of the pathology, can arrest or slow evolution. To the best of our knowledge, no studies have reported IOP increase in sickle-cell ONFH. The present study sought to show that intraosseous hyperpressure plays a role in the physiopathology of sickle-cell, like idiopathic, ONFH. MATERIALS AND METHODS: Sixteen intraosseous pressure (IOP) measurements were taken: eight in adult sickle-cell disease patients, four in sickle-cell trait carrying ONFH patients (AS) and four in non-sickle-cell ONFH patients (AA). Arterial blood-pressure equipment with bone-puncture needle was used to measure IOP in the great trochanter body. Three IOP measurements were made after zero calibration: before drilling (direct pressure: IOP-1), after hyperpressure test but before drilling (IOP-2), and after drilling (IOP-3). RESULTS: The present, admittedly short, series displayed elevated predrilling IOP-1 and IOP-2, reduced after drilling (IOP-3). Abnormal IOP fell after drilling performed for evolutive symptomatic ONFH. Significant differences in IOP-1 and IOP-2 were found, these being higher in the "sickle-cell disease" and "sickle-cell trait carriers" groups (p<0.05). Only in the sickle-cell groups was there a significant correlation between pain score and hyperpressure level, with significantly reduced pain after drilling. DISCUSSION: The elevated IOP levels found in symptomatic sickle-cell hips were comparable to those reported in the literature. Ischemia due to femoral head sinusoid occlusion by falciform globules with secondary intraosseous hyperpressure is the cause of the pain and of the onset and evolution of ONFH. The drilling tunnel acts as a safety valve, achieving real decompression of the segment involved and immediate postoperative reduction in or disappearance of pain. CONCLUSION: Measuring pressure is of diagnostic interest in sickle-cell disease patients with symptomatic hips. Manometry can be performed independently of surgery, under local anesthesia, and provides early confirmation of ONFH in geographic regions in which MRI is not readily available. It can be carried out very straightforwardly, without pressure sensor, using a simple water column (physiological saline) and three-way tap. Peroperative comparison of IOP-1 and IOP-3 is a means of assessing the effectiveness of decompression drilling.

[Study of the plantar arch: correlations between podometrical and radiological parameters. results of a prospective study of 79 cases]. / Etude de la voûte plantaire: corrélations entre des paramètres podométriques et radiologiques. Résultats d'une etude prospective de 79 cas.

The authors present a prospective study on the potential correlations between eight footprint parameters and three radiological parameters in the study of the plantar arch. Seventy nine patients were evaluated in 2001. The eight footprint parameters were as fellows : the arch angle, the Chippaux-Smirak's index, the Quamra's contact index 2,3 and 4, the Schwartz's footprint angle, the Staheli's arch index and the arch length index. The three radiological parameters were as fellows : the Djian-Annonier's angle, the Méary's angle and the calcaneal inclination. This prospective study confirms the best correlation, found in others studies, obtained between the Djian-Annonier's angle and the Chippaux-Smirak. The use of the Méary's angle and the calcaneal inclination is not justified because they have bad correlations with footprint parameters.

Theoretical study of the decrease in the femoral neck anteversion during growth.

This theoretical analysis tries to explain the decrease of the femoral neck anteversion during growth according to well-established concepts. In the frontal plane, it was demonstrated that the capital epiphyseal plate inclination allows the plate to remain perpendicular to the resultant force applied to the hip during gait. In the transversal plane, the projection of this force varies from -24 degrees, outwards and forwards (heel strike), to 20 degrees, outwards and backwards (toe off). A mathematical formula calculates the instantaneous coordinates of the plate in this plane during gait. This kinematic study points out that the physiological value of the capital epiphyseal plate anteversion at the end of the growth is theoretically the ideal value to obtain in the transversal or horizontal plane a perpendicular relation between the orientation of this plate and the projection of the resultant force during walking.

[The orthopedics-traumatology department]. / Le Service d'Orthopédie-Traumatologie.

The Department is involved in clinical and research activities. We pioneered the clinical application of "smart of Orthopaedic implants". The monitoring concept, bringing a high added value, helps in assessing fracture healing or implant fixation. The technique, featuring the 21st century, also requires advanced knowledge in biomaterials. Such implants have been used during the ESA Parabolic Flight Campaigns. These measurements are a prerequisite to establish prevention programs of the bone demineralisation during space flights but also in disuse osteoporosis. The Department is deeply involved in external fixation. In vitro studies of the mechanical insertion and holding parameters of external fixation pins have been performed to produce new implants, which efficiency has been proved by a clinical study. We defined original clinical principles of external fixation as its use in upper limb indications, to maintain microsurgery transplant, preserving devascularization and providing adequate fixation. Our biomechanical approach of the upper limb, now confirmed by others research groups, questioned old clinical concepts. The isokinetic evaluation assesses the dynamic function of articulations, i.e. after arthroplasty, and is also used for medico-legal evaluation. The clinical research touches orthopaedic (or systemic) diseases as algodystrophy, Kienböck disease, Kashing Beck. We conducted a multidisciplinary research on the effect of electromagnetic fields (EMF) on cells differentiation. In addition to possible healing properties, it helps as an objective support to analyse the exposure to the environmental EMF.

[Orthopedic immobilization]. / La contention orthopédique.

The classical plaster bandage was devised in the mid 19th century. Until recently, osteoarticular trauma has been treated mostly by plaster cast immobilisation using plaster of Paris. Synthetic materials have been introduced on the market place in the seventies, but they have not superseded the traditional plaster of Paris. The more recent thermoplastic materials are used to make splints and orthoses, particularly at the wrist and hand. The present review of the literature confirms that synthetic materials present better physical and mechanical properties than the traditional plaster of Paris. In addition, they are lighter, they are more resistant to humidity, they are more radiotransparent and they generate less dust when removed. However, they are less malleable and cause higher pressure in case of limb edema. Plaster of Paris therefore remains indicated in the acute posttraumatic or postoperative period. This material is also cheaper, but the pecuniary benefit is limited for several reasons, particularly because plaster of Paris is associated with a higher rate of cast replacement.

Analysis of the capital femoral line orientation. A CT scan study.

An accurate knowledge of the relationship between the neck and the epiphyseal plate at the end of growth is important for biomechanical investigations of femoral neck remodelling during childhood. Statistical data about the position of the epiphyseal femoral cartilage in relation to the neck axis at the end of the growth, are rare in the literature. As the trace of the epiphysis can be observed on a CT scan view of an adult hip, cadaver femurs were investigated to study this relationship and to avoid irradiation of children. The mean anteversion angle of the epiphyseal line towards the patient's coronal plane is 2.3 degrees. The plate is retroverted in an average of 8.2 degrees in relation to the neck axis and is related to neck anteversion. The more the neck is anteverted, the more the plate is retroverted.

The vacuum phenomenon: a CT sign of nonunited fracture.

OBJECTIVE: The purpose of this study was to describe on CT scans the presence of a gas collection within a bone fracture reflecting the vacuum phenomenon as a sign of nonunited fracture. CONCLUSION: A gas collection between fractured bone fragments suggests a nonunited fracture.

[Corrective osteotomy using Hoffmann II external fixators for extra-auricular malunion of the distal radius]. / Ostéotomie correctrice pour cal vicieux extra-articulaire du radius distal ostéosynthèsée par fixateur externe Hoffmann II.

The authors present the technique and clinical results of a corrective osteotomy for malunion following extra-articular fractures of the distal radius. External fixation allows restoration of the length of the radius with minimal damage to the periosteum. It allows early mobilization of the radiocarpal joint. The position of the distal pins provides intraoperative visual control of the angular correction. The minimal invasive approach decreases the risk of iatrogenic lesion of an extensor tendon or a sensitive branch of the radial nerve. This technique is easy and reliable.

Geometrical analysis of the femoral neck torsion.

By the geometrical analysis of three cross sections the surface along the femoral neck, the second moments of area and the major axes of symmetry are obtained. The surface passing through these axes determined in each section, from the lateral to the medial third of the neck, is one of the two anatomical surfaces of symmetry of the neck. The geometric structure defined by this surface is a helicoid. No plane, in the ordinary sense of the word, has to be defined in the femoral neck. At the trochanteric junction, the major axis is inclined about 17 degrees on the anteversion plane, twists anteriorly and becomes more horizontal to finish with a mean inclination of 60 degrees at the cephalic junction. Surprisingly, this twist and then the neck torsion are in opposite directions to that suggested by the bony markers, often taken as a reference and reported in the anatomical descriptions.

Concept, design and fabrication of smart orthopedic implants.

Extensive clinical experience has been built up using orthopaedic implants instrumented with strain gauges connected to a Wheatstone bridge by means of percutaneous leads. This research showed the medical relevance of the monitoring of the deformation of implants as a powerful tool to evaluate nursing and rehabilitation exercises, for tracing dangerous overloads and anticipating implant failure and also to observe the healing process. The IMPACT 3500 project focuses on the instrumentation of femoral implants with on board sensors: regular Benoist-Girard implants have been modified, to contain a 'sensing cell', and thoroughly tested in vitro and in vivo. The implant deformations are measured with resistive strain gauges, and the signal is transferred to a personal computer for processing and display, via a hard wired connection, or via a telemetry system. Two fully implantable wireless designs, called Linkstrain and Sealstrain, are powered from the outside by magnetic induction. As Sealstrain contains the whole telemetric system in its cavity, the highest miniaturization was required; this seriously deteriorates the efficiency of the inductive power link.

Tissues and bone adhesives--historical aspects.

Glues and adhesives attach to a surface principally involving molecular attraction, whereas cements mostly work through mechanical interlocking. The adhesive and its degradation products must be biocompatible: chemical, clinical, legal, physical aspects are considered; the toxicity of even minor components must be extremely reduced. The idea of bone bonding using biological materials has been proposed by Gluck, in Berlin, more than a century ago. Cements and adhesives have been used for the fixation of fractures, the repair of defects and the fixation of prostheses. The cements are initially liquid or plastic and conform with the irregularities in the substratum, producing better bonding on rough surfaces. Developed during the early 1950s, cyanocrylate adhesives attracted the medical community by their bonding strength and ability to bond in wet environments but reports of displacement of the fracture ends were followed by reports of high infection rates, nonunion, and severe local reactions. Polymethylmethacrylate does not form a chemical bond with bone but a mechanical bond, a weak bone-polymer joint. Charnley used self-curing acrylic cement to bond a femoral head prosthesis into a femur. When adhesives are used to bond tissues, the polymer acts as a barrier between the growing edges and delay healing; the adhesive tends to be rapidly isolated from the bone by a fibrotic, non-adhesive capsule. No proof exists concerning the osteogenic potential of fibrin sealing (FS); its beneficial effect on bone formation has been questioned even if there is some evidence that FS should influence the early phases of bone repair and may help to solve the problem of reattachment of small osteocartilagenous fragments following joint trauma.

Can algodystrophy be prevented after hand surgery?

Algodystrophy is characterized initially by an increase in arterial flow, an increase in blood pool, a decrease in microcirculatory velocity, and a loss of thermoregulatory control. These changes, producing the typical symptomatology, associated diffuse hand pain, diminished hand function, edema, and abnormal color and temperature, are believed now to correspond in most cases to an exaggeration of the normal post-traumatic inflammatory responses and are not the consequence of sympathetic damage. Algodystrophy may be prevented in most hand surgery patients by minimizing the normal postoperative inflammation, by increasing venous return (especially by avoiding plaster casts and constrictive dressings), by controlling post-traumatic pain, by promoting early active mobilization, and by reassuring the patient. If there is any sign of algodystrophy, three-phase bone scintigraphy should be obtained and treatment instituted immediately.

Lunatomalacia associated with congenital shortening of the ulna in Langer-Giedion syndrome: a case report.

A 22-year-old patient with type I trichorinophalangeal Langer-Giedion syndrome presented a stage 2 osteonecrosis of the lunate associated with congenital shortening of the ulna and carpal tunnel syndrome. The patient was treated by shortening osteotomy of the radius and median nerve neurolysis, with an excellent result. This case provides an additional piece of evidence associating ulnar-minus variance with lunatomalacia, and another argument in favor of the theory that Kienböck's disease results from microfractures sustained by the lunate under an abnormal stress distribution situation.

Radiocarpal articular pressures during the reduction of distal radius fractures.

OBJECTIVES: To measure in vivo radiocarpal articular pressures during closed reduction and external fixation of distal radius fractures. DESIGN: Intraoperative measurements using a sterile pressure sensitive sensor specially constructed for this application. SETTING AND PATIENTS: Ten patients with a closed distal radius fracture stabilized by radiometacarpal external fixation. Radiocarpal pressures measured during transarticular distraction, wrist palmar flexion, wrist ulnar inclination, and fracture reduction. MAIN OUTCOME MEASUREMENTS AND RESULTS: Transarticular distraction resulted in a substantial decrease of the articular pressure, averaging -158.1 mmHg. Palmar flexion resulted in a mean pressure increase of 91.8 mmHg. The reduction of the fracture using a combination of distraction, palmar flexion and ulnar deviation resulted in either an increase or decrease of articular pressure, but always with a tendency toward progressive normalization of the pressure, with a mean slope of 3.2 mmHg/min. CONCLUSIONS AND CLINICAL RELEVANCE: The phenomena leading to the reduction of distal radius fractures could be related in part to a decrease of the intraarticular pressure, which may be responsible for a suction effect on the intraarticular bone fragments.