[Analysis of the causes of fatal outcome in fractures of the upper third of the femur]. / Analiz prichin letal'nykh iskhodov pri perelomakh verkhnei treti bedrennoi kosti.

Analysis of 5-year mortality of 1348 patients with fractures of the proximal end of the femur is presented. The effectiveness of measures aimed at the prevention of developing complications has been assessed. The data obtained demonstrate the effectiveness of these measures.

[Human immune interferon: production and action]. / Chelovecheskii immunnyi interferon: produktsiia i deistvie.

The most marked production of immune interferon by human peripheral blood leukocytes and splenocytes stimulated with phytohemagglutinin (PHA) and staphylococcal enterotoxin A (SEA) was shown to be achieved when lymphoid cells are propagated under conditions of constant sparing mixing on roller apparatus at a temperature of 37 degrees +/- 0.5 degrees C. The resulting interferon was sensitive to low pH, thermolabile, inactivated by treatment with trypsin, and not neutralised by antisera to human alpha- and beta-interferons. The antiviral properties with regard to vesicular stomatitis and Semliki Forest viruses were practically similar in PHA- and SEA-induced interferon and human alpha- and beta-interferons. The capacity to inhibit colony formation by HeLa cells was 30 times higher in gamma-interferon than the antiproliferative activity of alpha- and beta-interferons.