Early experimental studies on hemoperfusion as a treatment modality for acute radiation disease.

First results of the studies on hemoperfusion therapy of acute radiation disease that were conducted in Kiev in 1976 are presented. In these studies, 69 mongrel dogs were exposed to irradiation at a dose of 525 rad (5.25 Gy). It was proved that hemoperfusion through uncoated synthetic activated carbons led to a noticeable increase in their survival rate, from 3.2% in the control group (n = 31) to 68.4% and 62.4% for the dogs that received extracorporeal treatment at 2 h (n = 19) and 24 h (n = 19) after irradiation, respectively.

[Transfusiologic technics for the prevention and treatment of acute renal failure in the DIC syndrome in children]. / Transfuziologicheskie metody profilaktiki i lecheniia ostroi pochechnoi nedostatochnosti pri DVS-sindrome u detei.

Experiences with the treatment of 38 children with acute renal insufficiency owing to the hemolytico-uremic syndrome suggest that the combination of hemolysis and hemosorption at early stages of the disease brings about a rapid elimination of uremic toxins, "middle" molecules included. The authors consider the content of the "middle" molecules in the plasma to be the most informative index showing the severity of the condition, hemosorption being the most effective method against endotoxicosis.

[Changes in suspension stability of donor conserved blood in contact with carbon adsorbents]. / Izmenenie suspenzionnoi ustoichivosti konservirovannoi donorskoi krovi pri kontakte s uglerodnymi adsorbentami.

A possibility is shown to normalize the suspension stability of donor long-term conserved blood when passing it through carbon adsorbents of a developed porous structure which are well compatible with blood. Relationship is established between a fall in the concentration of low-molecular acid products of metabolism as well as of conserved blood protein compounds due to interaction with the surface of carbon sorbents and an increase in electrophorectical erythrocyte mobility, and some decrease in aggregation and viscosity of blood.