RESUMO
BACKGROUND: Dermatofibrosarcoma protuberans (DFSP) is an uncommon malignant tumor of the skin, the diagnosis of which can be difficult not only clinically but also histologically. The tumor has a low metastatic potential, but tends to recur locally if removal is incomplete. METHODS: We reviewed the clinical and histologic features of 19 cases of DFSP, seen at the Department of Dermatology (14 cases) and Department of Surgery (5 cases) at the Hull Royal Infirmary between 1975 and 1992. RESULTS: There were only 19 cases of DFSP diagnosed from a population of 500,000 over a period of 17 years. None of the cases were diagnosed clinically prior to histologic diagnosis. The highest incidence was in the 4th decade of age. The most frequent site was on the head and neck. None of the lesions metastasized but there were a total of eight incidents of local recurrence in five patients. Histologically all the cases showed presence of storiform-pattern spindle-shaped cells and new collagen formation. CONCLUSIONS: Dermatofibrosarcoma protuberans is a soft tissue tumor that is often not recognized clinically due to its rarity and variable appearance. Local recurrence is frequent. A wide surgical excision is the treatment of choice.
Assuntos
Dermatofibrossarcoma/epidemiologia , Neoplasias Cutâneas/epidemiologia , Adolescente , Adulto , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Núcleo Celular/ultraestrutura , Criança , Colágeno , Dermatofibrossarcoma/patologia , Diagnóstico Diferencial , Feminino , Neoplasias de Cabeça e Pescoço/epidemiologia , Neoplasias de Cabeça e Pescoço/patologia , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Mitose , Invasividade Neoplásica , Recidiva Local de Neoplasia/epidemiologia , Recidiva Local de Neoplasia/patologia , Neoplasias Cutâneas/patologiaRESUMO
A study of the incidence of skin cancer over a 14-year period in the North Humberside area of the U.K. indicates a steady rise in the numbers of the four most common types of skin cancer. A steep increase in the incidence of squamous cell carcinoma of the skin compared with that of internal squamous cell carcinoma was also detected. Our findings emphasize the need for continuing public education about both the dangers of UV radiation and measures to reduce exposure.
Assuntos
Doença de Bowen/epidemiologia , Carcinoma Basocelular/epidemiologia , Carcinoma de Células Escamosas/epidemiologia , Surtos de Doenças , Melanoma/epidemiologia , Neoplasias Cutâneas/epidemiologia , Adolescente , Adulto , Distribuição por Idade , Idoso , Idoso de 80 Anos ou mais , Criança , Pré-Escolar , Inglaterra/epidemiologia , Neoplasias Esofágicas/epidemiologia , Feminino , Humanos , Incidência , Lactente , Masculino , Pessoa de Meia-Idade , Neoplasias Faríngeas/epidemiologia , Distribuição por Sexo , Neoplasias do Colo do Útero/epidemiologiaRESUMO
BACKGROUND: The Spitz nevus is a rare form of benign nevus, which may be confused with malignant melanoma. METHODS: We reviewed the clinical and histologic features of 29 cases of Spitz nevus, of which 20 were dealt with by our department of dermatology at the Hull Royal Infirmary between 1969 and 1990. The other nine cases were from the records of our pathology department dated between 1979 and 1991, of which seven of the lesions were excised by the surgeons and two by the general practitioners. RESULTS: In all the cases, the final diagnosis was established histologically. In three cases, there were difficulties histologically in excluding the diagnosis of malignant melanoma. All the lesions were solitary, and none of the lesions recurred following excision despite the possibility of incomplete excision in some cases. CONCLUSIONS: We found the size of the lesion and the age of the patient important factors to consider in the diagnosis of Spitz nevus. The small number of cases we encountered over a period of 22 years in a department that serves a population of around 500,000 emphasises the rarity of the condition.
Assuntos
Nevo Pigmentado , Neoplasias Cutâneas , Adolescente , Adulto , Criança , Pré-Escolar , Diagnóstico Diferencial , Feminino , Humanos , Masculino , Melanoma/diagnóstico , Nevo Pigmentado/diagnóstico , Nevo Pigmentado/patologia , Neoplasias Cutâneas/diagnóstico , Neoplasias Cutâneas/patologiaRESUMO
Seventy-eight cases of pilomatricoma are reported. The unexpected findings are new lesions occurring in middle and old age; the lack of association with other diseases; and the large number of lesions located deep in the skin. As contemporary knowledge of the nature of this disorder is advancing, it is suggested that the eponymous title be abandoned.
