RESUMO
Antibody levels following intradermal and intramuscular hepatitis B vaccination were compared in a group of university students matched for age and sex. Intradermal vaccination gave satisfactory antibody levels in females, but much lower levels than by the intramuscular route and an unacceptable failure rate in men. The cost implications of introducing a selective vaccination policy in health care workers are discussed.
Assuntos
Anticorpos Anti-Hepatite B/biossíntese , Vacinas contra Hepatite Viral/administração & dosagem , Adulto , Feminino , Vacinas contra Hepatite B , Humanos , Injeções Intradérmicas , Injeções Intramusculares , Masculino , Fatores SexuaisRESUMO
Ill health is often encountered by travellers. As medical students are encouraged to spend their electives overseas, it was considered worthwhile to study the morbidity experience of University of Bristol medical students and to see whether any additional preventive measures could be identified for them. The findings suggest that the quality of advice could be further improved for medical students undertaking their electives abroad. Additional preventive measures were suggested by the students themselves. The suggestions may also be useful for other groups of travellers.
Assuntos
Prevenção Primária , Estudantes de Medicina , Viagem , Nível de Saúde , HumanosAssuntos
Anti-Infecciosos Urinários/uso terapêutico , Cistite/tratamento farmacológico , Ácido Nalidíxico/análogos & derivados , Sulfametoxazol/uso terapêutico , Trimetoprima/uso terapêutico , 4-Quinolonas , Adolescente , Adulto , Anti-Infecciosos , Combinação de Medicamentos/uso terapêutico , Feminino , Humanos , Ácido Nalidíxico/uso terapêutico , Combinação Trimetoprima e SulfametoxazolAssuntos
Próstata/metabolismo , Hiperplasia Prostática/metabolismo , Testosterona/metabolismo , 17-Hidroxicorticosteroides/biossíntese , Androstanos/biossíntese , Androstenodiona/biossíntese , Androsterona/biossíntese , Animais , Radioisótopos de Carbono , Bovinos , Cromatografia em Papel , Cromatografia em Camada Fina , Desidroepiandrosterona/biossíntese , Di-Hidrotestosterona/biossíntese , Cavalos , Humanos , Masculino , Técnicas de Cultura de Órgãos , Esteróis/biossíntese , Fatores de Tempo , TrítioRESUMO
Slices of human prostatic adenocarcinoma obtained by transurethral resection were maintained in organ culture for 4 days. Preservation of histological appearance was good with little evidence of necrosis within the viable tissue. Slices of tumour cultured in the presence of testosterone showed a morphological change to a more differentiated type of neoplasm whereas explants cultured in the absence of steroid hormone, or with stilboestrol diphosphate, showed no change. In the case of a relatively anaplastic tumour, testosterone produced a significant increase in the number of mitotic figures seen.
