[Alcohol withdrawal syndrome dynamics during treatment with nooclerin (deanoli aceglumas)]. / Dinamika simptomov sindroma otmeny alkogolia v protsesse lecheniia nooklerinom (deanola atseglumat).

AIM: To study the efficacy of nooclerin (deanoli aceglumas) in alcohol withdrawal syndrome assessed by clinical and biochemical characteristics. MATERIAL AND METHODS: A multicenter, open, randomized, comparative study of nooclerin in the complex treatment of alcohol withdrawal syndrome included 90 patients. The patients were randomized into nooclerin group (n=55) and control group (n=35). RESULTS AND CONCLUSION: Nooclerin reduced alcohol withdrawal symptoms more significantly throughout the whole study period. There were significant between-group differences on the Clinical Institute Withdrawal Assessment of Alcohol Scale (CIWA-Ar) and the Multidimensional Fatigue Inventory (МFI-20). However, patients exhibited no excessive activity. No adverse side-effects were observed.

[Pychotherapy in patients with alcohol dependence and comorbid endogenous pathology]. / Psikhoterapiia bol'nykh s alkogol'noi zavisimost'iu i komorbidnoi éndogennoi patologiei.

AIM: To develop differential psychotherapeutic methods in the combined treatment of patients with alcohol dependence and comorbid paranoid schizophrenia. MATERIAL AND METHODS: Authors treated 154 patients using a specially designed psychotherapeutic program. The sample was randomized into the experimental and control groups. The experimental group received the psychotherapeutic program in contrast to the control group. RESULTS: The psychotherapeutic program based on the treatment of alcohol-dependence symptoms and patterns of coping with mental disorder symptoms was effective for the patients. Participation in the program allowed patients with alcohol dependence and comorbid schizophrenia to reduce manifestations of pathological craving for alcohol. CONCLUSION: The appropriate psychopharmacotherapy of endogenous disorder symptoms is an essential condition for successful psychotherapy, especially at the beginning of the treatment.

[The therapeutic alliance as a main factor of building cooperation during the treatment of patients with opiate addiction]. / Terapevticheskii al'ians kak osnovnoi faktor formirovaniia sotrudnichestva v protsesse lecheniia bol'nykh opioidnoi zavisimost'iu.

Objective. To assess an alliance-centred method of short-term psychotherapy (AP) in the formation of compliance in patients with opiate addiction. Material and methods. Authors studied 100 male inpatients with ICD-10 diagnosis Opioid Dependence (F11.2). Patients were stratified into main (with use of AP) and control groups. The tasks of short-term psychotherapy were to determine mutual goals for the patient and the physician and the interaction between them. Results and Conclusion. Based on some special quantitative psychological tests and correlation analysis, it was identified that AP stimulated compliance behaviour in patients with opioid dependence more effectively than traditional recommendations.

[Emotional and Cognitive Disturbances in Addictions: interactions and correlations]. / Émotsional'nye i kognitivnye narusheniia v strukture narkologicheskikh zabolevanii: vzaimovliianie i vzaimosviaz'

The literature data on the relationship between cognitive disorders and disorganized behavior influenced by affect in patients with addictions is reviewed. States of discomfort caused by withdrawal or pathological craving are discussed. A trend towards the development of integrative models based on the unity of cognitive and emotional processes is shown.

[Psychotherapy of alcoholics based on personality traits].

The article describes results of the development of the differentiated application of psychotherapeutic methods to the treatment of 120 patients with alcoholism basing on their personality characteristics. Psychotherapeutic programs oriented towards the characterologic features of patients are presented. These programs allowed to single out 4 groups of patients. The differentiated application of psychotherapy in these groups increased the effectiveness of treatment. As a result, the remission was achieved in 94 patients.

[Combination of gambling and alcohol addiction].

The data on clinical presentations, peculiarities of disease course, dynamics of gambling addiction in alcohol-addicted patients are presented. Ideation, affective, behavior and autonomic aspects in the structure of the syndrome of pathological craving are described. Peculiarities of clinical manifestations and dynamics of pathological craving, withdrawal syndrome and remission in this category of patients are specified.

[Alcohol addiction from the perspective of transactional analysis].

The article reviews the major causes creating the basis for the formation and development of alcohol addiction from the transactional analysis perspective. The disturbances of functioning of patient's ego states and main psychological games underlying the self-destructive life scripts are described. The main directions of psychotherapeutic aid are considered to be linked to bowl off or abandon a corresponding role.