The auditory stimulus facilitates memory guidance in distractor suppression in males with substance use disorder.

Introduction: Representations in working memory can affect distractor suppression in human visual search, and this process is modulated by a separate top-down cognitive control. An increasing body of research has demonstrated that patients with substance use disorder (SUD) have deficits in cognitive control over filtering interference by perceptual distractors. However, their ability to resist proactive interference from working memory has received comparatively less attention. Methods: Here, we investigate this issue by employing a working memory/visual search dual-task paradigm. An intervening gap-location search task was instructed to be performed while participants memorized a written color word, with congruent auditory information present during the memory encoding phase on half of the trials. Results: Results showed that there was a reliable response time (RT) advantage when the meaning of the memory sample agreed with the color of one of the distractors under the visual alone condition. However, such a result was only found in the control group. More importantly, both groups exhibited comparable facilitation under the audiovisual condition, with the facilitation effect appearing later in the SUD group. Furthermore, the facilitation effect was superior in magnitude and time course under the audiovisual condition to the visual alone condition. Discussion: These findings highlight how patients with SUD resist distractor interference at the memory level and extend our understanding of how working memory, selective attention, and audiovisual enhancement interact to optimize perceptual decisions in patients with SUD.

Differential effects of high-definition transcranial direct current stimulation (HD-tDCS) on attentional guidance by working memory in males with substance use disorder according to memory modality.

Information stored in working memory can guide perception selection, and this process is modulated by cognitive control. Although previous studies have demonstrated that neurostimulation over the left dorsolateral prefrontal cortex (lDLPFC) contributes to restore cognitive control among individuals with substance use disorder (SUD), there remains an open question about the potential stimulation effects on memory-driven attention. To address this issue, the present study adopted a combined working memory/attention paradigm while employing high-definition transcranial direct current stimulation (HD-tDCS) to stimulate the lDLPFC. Observers were asked to maintain visual or audiovisual information in memory while executing a search task, while the validity of the memory contents for the subsequent search task could be either invalid or neutral. The results showed a faint memory-driven attentional suppression effect in sham stimulation only under the audiovisual condition. Moreover, anodal HD-tDCS facilitated attentional suppression effect in both the strength and temporal dynamics under the visual-only condition, whereas the effect was impaired or unchanged under the audiovisual condition. Surprisingly, cathodal HD-tDCS selectively improved temporal dynamics of the attentional suppression effect under the audiovisual condition. The present study revealed the differential enhancement of HD-tDCS on cognitive control over visual and audiovisual memory-driven attention among individuals with SUD.

Pitch Improvement in Attentional Blink: A Study across Audiovisual Asymmetries.

Attentional blink (AB) is a phenomenon in which the perception of a second target is impaired when it appears within 200-500 ms after the first target. Sound affects an AB and is accompanied by the appearance of an asymmetry during audiovisual integration, but it is not known whether this is related to the tonal representation of sound. The aim of the present study was to investigate the effect of audiovisual asymmetry on attentional blink and whether the presentation of pitch improves the ability to detect a target during an AB that is accompanied by audiovisual asymmetry. The results showed that as the lag increased, the subject's target recognition improved and the pitch produced further improvements. These improvements exhibited a significant asymmetry across the audiovisual channel. Our findings could contribute to better utilizations of audiovisual integration resources to improve attentional transients and auditory recognition decline, which could be useful in areas such as driving and education.

Semantically congruent bimodal presentation modulates cognitive control over attentional guidance by working memory.

Although previous studies have well established that audiovisual enhancement has a promoting effect on working memory and selective attention, there remains an open question about the influence of audiovisual enhancement on attentional guidance by working memory. To address this issue, the present study adopted a dual-task paradigm that combines a working memory task and a visual search task, in which the content of working memory was presented in audiovisual or visual modalities. Given the importance of search speed in memory-driven attentional suppression, we divided participants into two groups based on their reaction time (RT) in neutral trials and examined whether audiovisual enhancement in attentional suppression was modulated by search speed. The results showed that the slow search group exhibited a robust memory-driven attentional suppression effect, and the suppression effect started earlier and its magnitude was greater in the audiovisual condition than in the visual-only condition. However, among the faster search group, the suppression effect only occurred in the trials with longer RTs in the visual-only condition, and its temporal dynamics were selectively improved in the audiovisual condition. Furthermore, audiovisual enhancement of memory-driven attention evolved over time. These findings suggest that semantically congruent bimodal presentation can progressively facilitate the strength and temporal dynamics of memory-driven attentional suppression, and that search speed plays an important role in this process. This may be due to a synergistic effect between multisensory working memory representation and top-down suppression mechanism. The present study demonstrates the flexible role of audiovisual enhancement on cognitive control over memory-driven attention.

Levels of neuroticism can predict attentional performance during cross-modal nonspatial repetition inhibition.

Inhibition of return (IOR) refers to the slower response to targets presented at previously attended locations, and such repetition-induced inhibition has been found to be differentially associated with personality traits. Although it has been well documented how personality traits affect spatial IOR, a mechanism associated with the attentional orienting network, there is not yet a consensus as to the relationship between personality traits and nonspatial repetition inhibition, a mechanism associated with the attentional executive network. The present study herein examined how the Big Five personality traits relate to cross-modal nonspatial repetition inhibition. Participants completed the NEO-PI-R and performed a cross-modal nonspatial repetition inhibition task built on the prime-neutral cue-target paradigm, in which the relationships of the identities and modalities between the prime and the target were manipulated. The results showed a significant nonspatial inhibitory effect and the effect was larger under the visual-auditory condition than under the auditory-visual condition. More importantly, neuroticism was associated with decreased cross-modal nonspatial inhibitory effect, presumably due to impaired attentional control. However, such a result was only found in the visual-auditory condition. We propose that retrieving previous prime representations under the visual-auditory condition requires a large consumption of cognitive resources, making inhibitory control more difficult for individuals with high neuroticism. These findings provide new insight into the influence of personality traits on attentional performance requiring nonspatial inhibitory control and enrich the relationship between neuroticism and repetition-induced inhibition.

Multisensory Enhancement of Cognitive Control over Working Memory Capture of Attention in Children with ADHD.

Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder in school-age children. Although it has been well documented that children with ADHD are associated with impairment of executive functions including working memory (WM) and inhibitory control, there is not yet a consensus as to the relationship between ADHD and memory-driven attentional capture (i.e., representations in WM bias attention toward the WM-matched distractors). The present study herein examined whether children with ADHD have sufficient cognitive control to modulate memory-driven attentional capture. 73 school-age children (36 with ADHD and 37 matched typically developing (TD) children) were instructed to perform a visual search task while actively maintaining an item in WM. In such a paradigm, the modality and the validity of the memory sample were manipulated. The results showed that under the visual WM encoding condition, no memory-driven attentional capture was observed in TD children, but significant capture was found in children with ADHD. In addition, under the audiovisual WM encoding condition, memory-matched distractors did not capture the attention of both groups. The results indicate a deficit of cognitive control over memory-driven attentional capture in children with ADHD, which can be improved by multisensory WM encoding. These findings enrich the relationship between ADHD and cognitive control and provide new insight into the influence of cross-modal processing on attentional guidance.