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1.
Biomed Res Int ; 2020: 4503463, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32879882

RESUMO

OBJECTIVE: Sympathetic blocks are used as an adjunct for pain management in the treatment of orthopedic and traumatic conditions. Stellate ganglion (ganglion stellatum) provides sympathetic innervation of the head, neck and cervicothoracic regions, and upper extremities. No study was found in the literature investigating the effects of stellate ganglion block performed in the upper extremity, on blood supply to bone, density, vascularization, and bone metabolism. Therefore, the objective of this study was to investigate the effects of stellate ganglion block on healing of closed forearm fractures that were induced in rats. Material and Methods. A total of 42 Wistar albino rats weighing between 398 and 510 g were used in this study. The rats were randomly divided into 2 groups with one group treated with stellate ganglion and the other included as the control group. In each 2 groups, a closed forearm fracture was created, confirmed with X-ray, and then stabilized by splint application. The forearm bones were examined with X-ray views on the same day and were then decalcified. RESULTS: When histological findings of the fracture region were examined, predominantly cartilage and less woven bone were found in 7 rats, equally distributed cartilage and immature bone in 14 rats, and predominantly imitation bone and less cartilage formation in 21 rats. In the control group, the agreement between the 1st and 2nd orthopedists for the radiological evaluation of bone formation was moderate. CONCLUSION: The group administered stellate ganglion block showed a more significant fracture healing.


Assuntos
Bloqueio Nervoso Autônomo/métodos , Consolidação da Fratura/fisiologia , Fraturas Fechadas/terapia , Gânglio Estrelado/efeitos dos fármacos , Acetaminofen/farmacologia , Analgésicos não Narcóticos/farmacologia , Animais , Cartilagem Articular/fisiopatologia , Membro Anterior/lesões , Fraturas Fechadas/diagnóstico por imagem , Fraturas Fechadas/fisiopatologia , Masculino , Osteogênese/fisiologia , Ratos Wistar
2.
Jt Dis Relat Surg ; 31(2): 246-254, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32584721

RESUMO

OBJECTIVES: This study aims to biomechanically and histopathologically investigate the effects of methylene blue (MB) on preventing postoperative adhesion in chickens undergoing full- thickness flexor tendon incision. MATERIALS AND METHODS: This study was performed between June 2017 and June 2018 on Hubbard JA 57 type chickens (age, 6 months; weight, 2.2±0.3 kg). Sixty-four tendons were studied in 32 chickens, including 16 in the control group and 16 in the experimental group. The second and third finger flexor digitorum profundus tendons of the left foot of each chicken were repaired primarily after a full-thickness incision approximately 1 cm proximal to the distal adhesion area. In the control (n=32) and experimental groups (n=32), 0.25 mL of normal saline and 0.25 mL of 1% MB solutions were applied locally to the surgical site, respectively. The operated limb was immobilized using a circular cast. 16 chickens were randomly selected in each group and examined at the fourth week, and the remaining 16 chickens were examined at the sixth week. Thirty-two of these tendons were evaluated using the Tang histopathological adhesion classification system, and the other 32 were evaluated with a biomechanical pull system. RESULTS: Adhesion was found to be less in the experimental group compared to the control group at the end of the fourth and sixth weeks both histopathologically and biomechanically. Furthermore, adhesion was significantly less in the experimental group at the end of the sixth week compared to the fourth week both histopathologically and biomechanically. CONCLUSION: Histopathological and biomechanical results show that MB, which has anti-inflammatory, antiseptic, antimicrobial and antioxidant effects, reduces adhesion during the healing process after tendon repair. We think that local MB application, particularly in surgeries performed after this type of injury, will be beneficial on early rehabilitation and functional results.


Assuntos
Azul de Metileno/farmacologia , Procedimentos Ortopédicos/efeitos adversos , Traumatismos dos Tendões/cirurgia , Tendões , Aderências Teciduais , Cicatrização/efeitos dos fármacos , Animais , Fenômenos Biomecânicos , Galinhas , Inibidores Enzimáticos/farmacologia , Modelos Anatômicos , Tendões/patologia , Tendões/fisiopatologia , Tendões/cirurgia , Aderências Teciduais/etiologia , Aderências Teciduais/prevenção & controle
3.
Ulus Travma Acil Cerrahi Derg ; 24(3): 185-190, 2018 May.
Artigo em Inglês | MEDLINE | ID: mdl-29786827

RESUMO

BACKGROUND: Montelukast is a selective leukotriene D-4 receptor antagonist, which specifically and reversibly inhibits cysteinyl leukotriene-1 receptor. The aim of this study was to investigate the protective effect of Montelukast on skeletal muscle reperfusion injury created as acute ischemia-reperfusion (IR) injury in Wistar-albino rats. METHODS: The study comprised 16 male Wistar-albino rats. The rats were randomly separated into two groups as control (IR) and treatment (IR+Montelukast). Ischemia was obtained using a femoral artery clamp. After reperfusion following a 2-hour ischemia, muscle samples were taken for biochemical and histopathological analyses. RESULTS: Malondialdehyde levels were determined to be at statistically higher levels in the control compared with that in the Montelukast group (p=0.002, p<0.01). The superoxide dismutase levels were determined to be at statistically higher level in the Montelukast group compared with that in the control group (p=0.001, p<0.01). In the histopathological examination of the ischemic muscles, edema, polymorinfiltration and erythrocyte extravasation levels were found to be statistically significant higher in the control group than in the Montelukast group. Edema, polymorphonuclear infiltration, and erythrocyte extravasation levels were observed to be significantly reduced in the treatment group compared with that in the control. CONCLUSION: In this model of skeletal muscle acute IR injury, the protective effect of Montelukast against skeletal muscle reperfusion injury was emphasized. We concluded that Montelukast could accelerate functional recovery in the extremity by limiting the local and systemic complications caused by reperfusion in cases such as extremity trauma with vascular injuries and extremity surgery with prolonged tourniquet application. However, further experimental and clinical studies are required to confirm this effect.


Assuntos
Acetatos/farmacologia , Músculo Esquelético , Substâncias Protetoras/farmacologia , Quinolinas/farmacologia , Traumatismo por Reperfusão/patologia , Animais , Ciclopropanos , Masculino , Malondialdeído , Músculo Esquelético/efeitos dos fármacos , Músculo Esquelético/lesões , Músculo Esquelético/patologia , Distribuição Aleatória , Ratos , Ratos Wistar , Sulfetos
4.
Acta Orthop Traumatol Turc ; 47(3): 201-7, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-23748620

RESUMO

OBJECTIVE: The purpose of the present study was to compare the effectiveness of platelet-rich plasma (PRP) + microfracture and microfracture treatments in the healing of chronic focal chondral defects. METHODS: The study included 57 adult male Sprague-Dawley rats. Forty-two rats were divided into three groups of 14 rats with a chondral defect (control, microfracture only, PRP+microfracture). The remaining 15 rats were used to produce the PRP preparation. The rats were then euthanatized at 3 and 6 weeks after treatment and examined. Histological analysis using the modified Pineda scoring system and immunohistochemical staining for Type 2 collagen were performed. RESULTS: At both time intervals, control group histological scores (Week 3: 8.8±1.2, Week 6: 8.5±0.7) were higher than microfracture (Week 3: 6.8±1.0, Week 6: 7.1±0.6) and PRP+microfracture (Week 3: 6.4±1.3, Week 6: 5.7±1.2) scores (p<0.05). The microfracture group score was higher at Week 6 than the PRP+microfracture group (p<0.05). The degree of Type 2 collagen staining was higher at Week 6 in the PRP+microfracture group and was unique in showing staining at the cell membrane. CONCLUSION: The addition of PRP application to microfracture treatment appears to enhance cartilage healing in chronic focal chondral defects.


Assuntos
Regeneração Óssea/efeitos dos fármacos , Cartilagem Articular/efeitos dos fármacos , Plasma Rico em Plaquetas , Animais , Biomarcadores/metabolismo , Cartilagem Articular/metabolismo , Condrócitos/metabolismo , Doença Crônica , Colágeno Tipo II/biossíntese , Modelos Animais de Doenças , Injeções Intralesionais , Extremidade Inferior/cirurgia , Masculino , Ratos , Ratos Sprague-Dawley , Cicatrização
5.
Med Glas (Zenica) ; 10(1): 81-5, 2013 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-23348167

RESUMO

UNLABELLED: To compare only partial matrixectomy and combination techniques (partial matrixectomy + phenol application) in the treatment of patients with an ingrown toenail in terms of recurrence, residual pain level and time of return to daily activities. METHODS: The study included 118 patients with moderately ingrown toenails who were unresponsive to conservative treatment together with severely ingrown toenail patients. Of these patients, 76 cases were treated with a partial matrixectomy technique and 42 patients received combination treatment. Patients having nail infection received preoperative oral antibiotics. RESULTS: Of 118 patients, 87 were males and 31 were females. The disease relapsed in seven (9.2%) of the patients treated with the partial matrixectomy technique, and in two (4.8%) patients from the combination treatment group (p=0.5). No statistically significant difference was found between the groups in terms of return time to daily activities (p=0.5) nor in terms of residual pain (p=0.7). CONCLUSIONS: Treatment costs and operation times of patients who underwent phenol application in addition to partial matrixectomy were found to be higher compared to only partial matrixectomy, however combined therapy was not found to be superior to only partial matrixectomy in terms of recurrence, post-op pain and return to daily activities.


Assuntos
Unhas Encravadas/terapia , Fenóis/administração & dosagem , Soluções Esclerosantes/administração & dosagem , Administração Cutânea , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Antibacterianos/uso terapêutico , Feminino , Hallux , Humanos , Masculino , Pessoa de Meia-Idade , Unhas Encravadas/complicações , Unhas Encravadas/cirurgia , Procedimentos Ortopédicos/métodos , Dor Pós-Operatória/prevenção & controle , Satisfação do Paciente , Recidiva , Fatores de Risco , Resultado do Tratamento
6.
Acta Orthop Traumatol Turc ; 46(4): 301-7, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-22951762

RESUMO

OBJECTIVE: The purpose of this experimental study was to analyze the effects of local autologous platelet-rich plasma (PRP) injection on tendon-to-bone healing in a rotator cuff repair model in rats. METHODS: Rotator cuff injury was created in 68 left shoulders of rats. PRP was obtained from the blood of an additional 15 rats. The 68 rats were divided into 4 groups with 17 rats in each group; PRP group (Week 2), control group (Week 2), PRP group (Week 4), and control group (Week 4). Platelet-rich plasma or saline was injected to the repair area intraoperatively. Rats were sacrificed 2 and 4 weeks after the surgery. Histological analysis using a semiquantitative scoring was performed on 7 rats per group. Tendon integrity and increases in vascularity and inflammatory cells and the degree of new bone formation were evaluated and compared between the groups. The remaining tendons (n=10) were mechanically tested. RESULTS: Degree of inflammation and vascularity were less in the study group at both time intervals (p<0.05). Tendon continuity was better in the study group at 2 weeks (p<0.05). Obvious new bone formation was detected in the control group at 4 weeks (p<0.05). Biomechanically, platelet-rich plasma-treated specimens were stronger at 2 weeks (p<0.05). CONCLUSION: Local autologous PRP injection may have beneficial effects on initial rotator cuff tendon-to-bone healing and enhance initial tendon-to-bone healing remodeling. This may represent a clinically important improvement in rotator cuff repair.


Assuntos
Plasma Rico em Plaquetas , Lesões do Manguito Rotador , Traumatismos dos Tendões/terapia , Cicatrização , Animais , Modelos Animais de Doenças , Seguimentos , Injeções , Período Intraoperatório , Masculino , Ratos , Ratos Sprague-Dawley , Procedimentos de Cirurgia Plástica , Manguito Rotador/patologia , Manguito Rotador/cirurgia , Traumatismos dos Tendões/patologia
7.
Middle East J Anaesthesiol ; 21(1): 93-8, 2011 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-21991739

RESUMO

BACKGROUND: In this prospective study we aimed at examining the effects of pneumatic tourniquet on intraocular pressure during elective knee surgery. METHOD: Twenty patients undergoing elective knee surgery under general anesthesia with tracheal intubation were inluded the study. Anesthesia was induced with pentothal, rocuronium and fentanyl, then maintained with sevoflurane and nitrous oxide in oxygen. Intraocular pressure measurements were performed at 7 time points; awake (baseline), following induction, following tracheal intubation, just before tourniquet inflation, after the inflation of tourniquet, before tourniquet deflation, after the deflation of the tourniquet. RESULTS: Baseline IOP was 15 +/- 1 mmHg. Following the induction of anesthesia IOP was reduced significantly (12 +/- 1 mmHg) (p < 0.05), then increased to 16 +/- 1 mmHg after tracheal intubation (p < 0.05). IOP was significantly higher after tourniquet inflation compared with just before (13 +/- 1 mmHg vs 16 +/- 1 mmHg recpectively) (p < 0.05). There was no significant difference between the IOP measurements after the inflation and before the deflation of the tourniquet (p > 0.05). The lowest value was 12 +/- 0 mmHg measured after the tourniquet loosened and it was significant compared with the baseline and the measurement performed before deflation of the tourniquet (16 +/- 0 mmHg) (p < 0.05). CONCLUSION: Pneumatic tourniquet may cause a significant IOP increase in patients performing knee surgery under general anesthesia.


Assuntos
Pressão Intraocular , Joelho/cirurgia , Torniquetes , Pressão Sanguínea , Feminino , Frequência Cardíaca , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos
8.
Eklem Hastalik Cerrahisi ; 22(1): 43-7, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-21417986

RESUMO

OBJECTIVES: In this study we evaluated the effects of montelukast, a leukotriene-receptor antagonist, on fracture healing, and investigated the hypothesis that enhanced fracture healing would be observed with montelukast in a rat tibia fracture model. MATERIALS AND METHODS: Sixty adult (6 months old) female Wistar albino rats (mean weight 220 g, range 210-270 g) were randomly divided into two groups: a montelukast group (n=30) and a control group (n=30). Closed tibia fractures were created and fixed by intramedullary Kirschner wire. The rats were sacrificed three and six weeks after the fractures. Radiological and histological evaluations were performed, and bone mineral density was measured. RESULTS: Three rats died in the montelukast group, whereas only one died in the control group during the study. Initial weight and weight gain at the 3rd and 6th weeks were not significantly different between the groups (p>0.05). Bone mineral densities in the control and study groups were 0.13±0.009 gr/cm2, and 0.13±0.01 gr/cm2 at week three and 0.16±0.02 gr/cm2, and 0.13±0.01 gr/cm2 at week six, respectively. Histopathological scores in the control and study groups were 3.42±0.6, and 3.0±0.0 at week three and 3.5±0.5, and 3.4±0.8 at week six, respectively. Radiological scores in the control and study groups were 1.19±0.6, and 1.0±0.6 at week three and 3.0±0.8, and 2.9±0.9 at week six, respectively. There were no significant differences between the two groups in any parameters evaluated at either time interval (p>0.05). CONCLUSION: Our study failed to show a possible positive effect of leukotriene receptor inhibition on fracture healing at the 3rd and 6th postoperative weeks.


Assuntos
Acetatos/farmacologia , Consolidação da Fratura/efeitos dos fármacos , Fraturas Fechadas/tratamento farmacológico , Antagonistas de Leucotrienos/farmacologia , Quinolinas/farmacologia , Fraturas da Tíbia/tratamento farmacológico , Absorciometria de Fóton , Animais , Densidade Óssea/efeitos dos fármacos , Ciclopropanos , Feminino , Fraturas Fechadas/diagnóstico por imagem , Fraturas Fechadas/patologia , Distribuição Aleatória , Ratos , Ratos Wistar , Sulfetos , Fraturas da Tíbia/diagnóstico por imagem , Fraturas da Tíbia/patologia , Resultado do Tratamento
9.
J Orthop Res ; 29(1): 138-42, 2011 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-20726035

RESUMO

The aim of this study was to evaluate the effect of strontium ranelate (SrR) on fracture healing in the osteoporotic rat model. Forty female Sprague-Dawley rats aged 3 months were enrolled in the study. Osteoporosis was induced by bilateral ovariectomy and subsequent daily heparin injection started 1 week after surgery and lasted for 4 weeks. Osteoporosis was confirmed by a reduction of bone mineral density (BMD). Twenty of the osteoporotic rats were assigned to the SrR group and the remaining 20 to the control group. An open right tibial midshaft transverse fracture was created and then an intramedullary fixation was performed. SrR group was treated by 450 mg/kg/day SrR per oral. Six weeks after surgical induction of fracture, all animals were sacrificed. One animal from each group died after ovariectomy. Two tibiae from the control group failed to unite. SrR-treated group showed higher mechanical strength and fracture stiffness when compared to the control group (p = 0.006, p = 0.001, respectively). SrR-treated group had mature woven bone or predominantly woven bone compared with osteoporotic control group (p = 0.038). SrR-treated group's callus maturity was significantly higher than control group (p = 0.001). SrR is associated with better fracture healing in the osteoporotic rat model.


Assuntos
Conservadores da Densidade Óssea/farmacologia , Consolidação da Fratura/efeitos dos fármacos , Compostos Organometálicos/farmacologia , Fraturas por Osteoporose/fisiopatologia , Tiofenos/farmacologia , Animais , Fenômenos Biomecânicos , Densidade Óssea/efeitos dos fármacos , Modelos Animais de Doenças , Feminino , Ratos , Ratos Sprague-Dawley
10.
J Orthop Res ; 28(10): 1368-72, 2010 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-20839321

RESUMO

Treatment of implant-related chronic osteomyelitis is often difficult and usually consists of implant removal, extensive surgical debridement, and prolonged antibiotic use. This study was performed to assess the efficacy of moxifloxacin compared to a glycopeptide, teicoplanin in chronic implant-related methicillin-sensitive Staphylococcus aureus (MSSA) osteomyelitis. The left femoral medullar cavities of 60 Wistar male rats were contaminated with 100 µl of 10(8) cfu/ml methicillin-sensitive S. aureus (ATCC 29213) and Kirschner wires were placed into the medulla of the femur. After 6 weeks, rats were randomly divided into five groups. In two groups, the Kirschner wires were removed. Experimental groups were as follows: group 1: contaminated, Kirschner wire inside, received teicoplanin; group 2: contaminated, Kirschner wire removed, received teicoplanin; group 3: contaminated, Kirschner wire inside, received moxifloxacin; group 4: contaminated, Kirschner wire removed, received moxifloxacin; group 5: contaminated, Kirschner wire inside, no antibiotics (control group). Groups 1 and 2 received teicoplanin (20 mg/kg once daily), whereas groups 3 and 4 received moxifloxacin (10 mg/kg twice daily) intraperitoneally for 28 days. At the end of the treatment, animals were sacrificed by inhalation anesthesia with ether and femora were retrieved and bacterial counts (cfu/g) were determined. Bacterial counts in all study groups were significantly reduced relative to the control. The decrease of bacterial counts was more prominent in group 4 compared to group 1 (p = 0.001) and group 2 (p = 0.003). Moxifloxacin therapy is an effective alternative to teicoplanin for chronic implant-related MSSA osteomyelitis.


Assuntos
Antibacterianos/uso terapêutico , Compostos Aza/uso terapêutico , Osteomielite/tratamento farmacológico , Infecções Relacionadas à Prótese/tratamento farmacológico , Quinolinas/uso terapêutico , Teicoplanina/uso terapêutico , Animais , Antibacterianos/administração & dosagem , Compostos Aza/administração & dosagem , Doença Crônica , Modelos Animais de Doenças , Fluoroquinolonas , Injeções Intraperitoneais , Masculino , Moxifloxacina , Osteomielite/microbiologia , Infecções Relacionadas à Prótese/complicações , Quinolinas/administração & dosagem , Ratos , Ratos Wistar , Infecções Estafilocócicas/complicações , Infecções Estafilocócicas/tratamento farmacológico , Staphylococcus aureus , Teicoplanina/administração & dosagem , Resultado do Tratamento
11.
Knee Surg Sports Traumatol Arthrosc ; 18(12): 1779-84, 2010 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-20549186

RESUMO

Different surgical techniques exist for biceps tenodesis. The most secure fixation technique is with interference screws. The purpose of the study was to compare the biomechanical performance of three different interference screw biceps tenodesis fixation methods, which involve different tunnel preparation methods. Using a sheep shoulder model and metal interference screws, a bone wedge technique was compared to serial tunnel dilation and a control group. After a preload, all repairs were cyclically loaded (20-60 N) for 100 cycles followed by destructive testing. Biceps tenodesis using an interference screw--bone wedge technique showed statistically lower cyclic displacement (8.1 ± 6.4 mm) than serial dilatation with an interference screw (21.3 ± 8.4 mm) or interference screw fixation alone (18.3 ± 8.3 mm) (P = 0.02). There were no statistically significant differences in ultimate failure strength for any of the interference screw biceps tenodesis techniques tested. The tunnel preparation method chosen for interference screw fixed biceps tenodesis can have a positive effect on tenodesis performance. Using the bone wedge technique may allow a more rapid rehabilitation program applicable for the traumatic biceps tendon rupture seen in young, athletic patients with high demands.


Assuntos
Parafusos Ósseos , Teste de Materiais , Tenodese/instrumentação , Animais , Feminino , Modelos Animais , Procedimentos Ortopédicos , Ovinos , Estresse Mecânico
12.
Orthopedics ; 33(2): 84-91, 2010 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-20192142

RESUMO

Lateral epicondylitis is a common disorder characterized by pain and tenderness over the lateral epicondyle. It occurs most frequently as a result of minor, unrecognized trauma during sports activities and occupation-related physical activities. The goal of this study was to evaluate the short-, medium-, and long-term effects of corticosteroid injection, autologous blood injection, and extracorporeal shock wave therapy in the treatment of lateral epicondylitis.Sixty patients (32 women, 28 men) with lateral epicondylitis were randomly divided into 3 groups: group 1 received a corticosteroid injection; group 2, an autologous blood injection, and group 3, extracorporeal shock wave therapy. Thomsen provocative testing, upper extremity functional scores, and maximal grip strength were used for evaluation. Outcomes were assessed at 4, 12, 26, and 52 weeks. Corticosteroid injection gave significantly better results for all outcome measures at 4 weeks; success rates in the 3 groups were 90%, 16.6%, and 42.1%, respectively. Autologous blood injection and extracorporeal shock wave therapy gave significantly better Thomsen provocative test results and upper extremity functional scores at 52 weeks; the success rate of corticosteroid injection was 50%, which was significantly lower than the success rates for autologous blood injection (83.3%) and extracorporeal shock wave therapy (89.9%). Corticosteroid injection provided a high success rate in the short term. However, autologous blood injection and extracorporeal shock wave therapy gave better long-term results, especially considering the high recurrence rate with corticosteroid injection. We suggest that the treatment of choice for lateral epicondylitis be autologous blood injection.


Assuntos
Corticosteroides/administração & dosagem , Transfusão de Sangue Autóloga/métodos , Litotripsia/métodos , Cotovelo de Tenista/diagnóstico , Cotovelo de Tenista/terapia , Adulto , Terapia Combinada , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Resultado do Tratamento
13.
J Med Case Rep ; 4: 47, 2010 Feb 09.
Artigo em Inglês | MEDLINE | ID: mdl-20181137

RESUMO

INTRODUCTION: Patellar tendon ossification is a rare pathology that may be seen as a complication after sleeve fractures of the tibial tuberosity, total patellectomy during arthroplasty, intramedullary nailing of tibial fractures, anterior cruciate ligament reconstruction with patellar tendon autograft and knee injury without fracture. However, its occurrence after partial patellectomy surgery has never been reported in the literature. CASE PRESENTATION: We present the case of a 35-year-old Turkish man with a comminuted inferior patellar pole fracture that was treated with partial patellectomy. During the follow-up period, his patellar tendon healed with ossification and then ruptured from the inferior attachment to the tibial tubercle. The ossification was excised and the tendon was subsequently repaired. CONCLUSION: To the best of our knowledge, this is the first report of patellar tendon ossification occurring after partial patellectomy. Orthopaedic surgeons are thus cautioned to be conscious of this rare complication after partial patellectomy.

14.
Eklem Hastalik Cerrahisi ; 20(3): 149-55, 2009.
Artigo em Inglês | MEDLINE | ID: mdl-19958271

RESUMO

OBJECTIVES: The aim of this study was to evaluate the results of free anterolateral thigh (ALT) flap reconstruction for large and complex soft tissue defects of forearm and hand. PATIENTS AND METHODS: Thirteen patients (11 males, 2 females; mean age 32.5 years; range 18 to 55 years) underwent free ALT flap reconstruction for forearm and hand defects. The etiology of defects was crush injury in nine patients, tumor excision in two patients, electric burn in one patient, and unstable scar excision in one patient. In five patients a flow through ALT flap was used to reconstruct vascular defects. In tree patients a vascularised fascial ALT flap was used to reconstruct the tendon defects and in five patients neurosensory ALT flap was used. Patients were followed for 44+/-14.6 months. Chen classification was used to evaluate functional outcomes at the end of the postoperative first year. RESULTS: All flaps survived completely in 11 patients. In the other two patients marginal necrosis was observed. These areas with necrosis healed after debridement and daily dressings. The functional results were satisfactory in 11 patients according to Chen classification (6 patients Chen I and 5 patients Chen II) and poor in two patients (Chen III). CONCLUSION: The anterolateral thigh flap represents an excellent option for covering various complex defects in the forearm and hand. The flap provides a thin, pliable, vascularized tissue for covering the exposed tendons, nerves, bones, and reconstruct deficiencies.


Assuntos
Antebraço/anormalidades , Antebraço/cirurgia , Deformidades Congênitas da Mão/cirurgia , Retalhos Cirúrgicos , Adolescente , Adulto , Desbridamento , Face/cirurgia , Feminino , Sobrevivência de Enxerto , Humanos , Masculino , Pessoa de Meia-Idade , Necrose , Retalhos Cirúrgicos/efeitos adversos , Tendões/anormalidades , Tendões/cirurgia , Adulto Jovem
15.
Arch Orthop Trauma Surg ; 129(12): 1721-6, 2009 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-19381661

RESUMO

INTRODUCTION: Ethanol has a suppressive effect on inflammation and the immune system, but the effect of ethanol on tendon healing in vivo has not been studied. The purpose of this study was to investigate the histological and biomechanical effects of ethanol intake on tendon healing in a rat tendon injury model. MATERIALS AND METHODS: Forty-seven rats were randomly assigned to either ethanol or control groups. Progressively increasing concentrations of ethanol combined with glucose were administered to these rats in their drinking water. After 1 week, the Achilles tendon of each rat was injured proximal to its insertion on the calcaneus. All rats were euthanized at 4 weeks. The tendons were evaluated both histologically and biomechanically. The histologic examination of these tendons was done using a semi-quantitative 4-point scale to rate cell morphology, the degree of ground substance staining, collagen organization, and vascular changes. Load to failure (N) strength was obtained with biomechanical testing. RESULTS: Tendon failure loads were lower in the ethanol group (31.6 +/- 8.8 N) than in the control group (39.7 +/- 8.2 N) (P = 0.04). Histologic tenocyte scores were higher in the ethanol group (1.90 +/- 0.73) than the control group (0.9 +/- 0.73) (P = 0.01). CONCLUSION: Ethanol ingestion resulted in abnormal tenocyte morphology, disorganized collagen bundles with a tendency toward increased tenocyte number, and neovascularization 3 weeks after the tendon injury indicating delayed and abnormal healing. The healing tendons in the alcohol treated group failed at statistically lower loads than the control group.


Assuntos
Tendão do Calcâneo/lesões , Etanol/farmacologia , Cicatrização/efeitos dos fármacos , Tendão do Calcâneo/patologia , Tendão do Calcâneo/fisiopatologia , Animais , Fenômenos Biomecânicos , Colágeno/metabolismo , Feminino , Ratos , Ratos Wistar
16.
J Child Orthop ; 3(1): 27-31, 2009 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-19308609

RESUMO

PURPOSE: Biomechanic factors play a role in the pathogenesis of knee osteoarthritis. The aim of the study was to find out whether there is a relation between femoral, acetabular anteversions, anterior, posterior acetabular coverages and primary osteoarthritis of the knee. METHODS: Thirty patients with primary osteoarthritis of the knee and 29 control subjects were enrolled into the study. Femoral anteversion, acetabular anteversion, McKibbin's instability index, anterior acetabular sector and posterior acetabular sector angles were measured using tomographic scanograms. RESULTS: There was no difference between groups for each parameter (P > 0.05). CONCLUSION: This study did not show any relationship between the axial plane changes in the hip joint and primary knee osteoarthritis.

17.
J Am Podiatr Med Assoc ; 99(2): 108-13, 2009.
Artigo em Inglês | MEDLINE | ID: mdl-19299346

RESUMO

BACKGROUND: To determine the effectiveness of four different local injection modalities in the treatment of plantar fasciitis. METHODS: In a prospective randomized multicenter study of plantar fasciitis, 100 patients were divided into four equal groups and were treated using four different methods of local injection: group A was treated with 2 mL of autologous blood alone; group B, an anesthetic (2 mL of lidocaine) combined with peppering; group C, a corticosteroid (2 mL of triamcinolone) alone; and group D, a corticosteroid (2 mL of triamcinolone) combined with peppering. The outcome was defined by using a 10-cm visual analog scale and modified criteria of the Roles and Maudsley score 3 weeks and 6 months after the injection and compared with the pretreatment condition. RESULTS: The successful results in all of the groups after injections were higher than those in the pretreatment condition (P = .000). In groups C and D, in which local corticosteroid injections were used, excellent results were obtained, with superior effect in the group in which peppering was used (P < .05). CONCLUSIONS: In the treatment of plantar fasciitis, combined corticosteroid injections and peppering is effective and produces better clinical results.


Assuntos
Anestésicos Locais/administração & dosagem , Fasciíte Plantar/tratamento farmacológico , Glucocorticoides/administração & dosagem , Injeções Subcutâneas/métodos , Lidocaína/administração & dosagem , Triancinolona/administração & dosagem , Adulto , Idoso , Fasciíte Plantar/complicações , Fasciíte Plantar/diagnóstico por imagem , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Radiografia , Resultado do Tratamento
18.
Clin Orthop Relat Res ; 467(7): 1807-12, 2009 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-19052824

RESUMO

UNLABELLED: Computed tomography (CT) frequently is used to determine torsional abnormalities. However, its use in clinical practice may be limited. We present a new method for measuring tibial torsion using conventional radiographs. We compared the method with several clinical methods and with CT measurement in 44 lower extremities of 25 subjects. The radiographic method agreed well with all of the clinical methods, and this agreement was better than agreement between CT and clinical examination. The best agreement was between thigh-foot angle and the radiographic method. The proposed radiographic measurement is a practical method for evaluation of tibial torsion in outpatient clinics without the need for specialized equipment. LEVEL OF EVIDENCE: Level II, diagnostic study.


Assuntos
Doenças Ósseas/diagnóstico por imagem , Radiografia/métodos , Radiografia/normas , Tíbia/diagnóstico por imagem , Anormalidade Torcional/diagnóstico por imagem , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Variações Dependentes do Observador , Pacientes Ambulatoriais , Projetos Piloto , Radiografia/estatística & dados numéricos , Reprodutibilidade dos Testes , Adulto Jovem
19.
Cases J ; 2: 9341, 2009 Dec 17.
Artigo em Inglês | MEDLINE | ID: mdl-20062597

RESUMO

Patellar tendinopathy is characterized by activity-related anterior knee pain. It is most commonly related to sports activity, but has also been reported in the non-athletic population. Most injuries are caused by microtrauma, resulting in tendinitis or tendinosis. Extraskeletal paraarticular osteochondromas, which occur in the soft tissues near the joint, are rare. The infrapatellar fat pad and joint capsule are the most common sites of these tumors. Here, a case of patellar tendinitis caused by an extraskeletal paraarticular osteochondroma is reported. The symptoms included intensifying pain upon flexion and a palpable click that was located at the medial side of the mass. The patient was pain-free within 3 weeks after excision of the tumor and the clicking disappeared. To our best knowledge, no other case of patellar tendinitis caused by an extraskeletal paraarticular osteochondroma has been reported in the English literature.

20.
Acta Orthop Belg ; 74(6): 846-50, 2008 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-19205334

RESUMO

Minimally invasive percutaneous plate osteosynthesis (MIPPO) has well-documented biological advantages and appears to be a reasonable treatment option for complex femoral and tibial fractures. However additional radiation exposure during reduction of the fracture, application of the plate to the bone and screw fixation is one of the disadvantages of this technique. We describe a technical trick for screw fixation in MIPPO with locking compression plates which decreases the duration of fluoroscopy use during the operation.


Assuntos
Parafusos Ósseos , Fraturas do Fêmur/cirurgia , Fixação Interna de Fraturas/métodos , Fraturas da Tíbia/cirurgia , Adolescente , Adulto , Idoso , Fios Ortopédicos , Feminino , Fluoroscopia , Humanos , Masculino , Pessoa de Meia-Idade , Procedimentos Cirúrgicos Minimamente Invasivos , Adulto Jovem
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