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1.
Qual Saf Health Care ; 14(2): 99-106, 2005 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-15805454

RESUMO

OBJECTIVE: Electronic medical records seldom integrate performance indicators into daily operations. Assessing quality indicators traditionally requires resource intensive chart reviews of small samples. We sought to use an electronic medical record to assess use of beta-adrenergic antagonist medications (beta-blockers) following myocardial infarction, to compare a standardized manual assessment with assessment using electronic medical records, and to discuss potential for future integration of performance indicators into electronic records. DESIGN: Cross-sectional data analysis. SETTING: An urban academic medical center. PARTICIPANTS: US Medicare beneficiaries 65 years of age or older, admitted to hospital with myocardial infarction between 1995 and 1999. MEASUREMENTS AND MAIN RESULTS: Manual chart review was compared with a computer driven assessment of electronic records. Administration of beta-blockers and cases excluded from use of beta-blockers were measured, based on Medicare criteria. Among 4490 older adults, 391 (4%) of 9018 hospital admissions contained codes for myocardial infarction. In 323 (83%) of the 391 hospital admissions, criteria for excluding beta-blockers were met; 235 (60%) were excluded due to heart failure. Of 68 hospital admissions for myocardial infarction that did not meet exclusion criteria, physicians prescribed beta-blockers in 49 (72%) on admission and 42 (62%) at discharge. Compared with manual chart review, electronic review had a sensitivity of 83-100% and led to fewer false negative findings. CONCLUSIONS: An electronic medical records system can be used instead of chart review to measure use of beta-blockers after myocardial infarction. This should lead to integration of real time automated performance measurement into electronic medical records.


Assuntos
Antagonistas Adrenérgicos beta/uso terapêutico , Revisão de Uso de Medicamentos/métodos , Auditoria Médica , Sistemas Computadorizados de Registros Médicos , Infarto do Miocárdio/tratamento farmacológico , Integração de Sistemas , Centros Médicos Acadêmicos , Idoso , Estudos Transversais , Hospitais Urbanos , Humanos , Indiana , Medicare/normas , Indicadores de Qualidade em Assistência à Saúde
3.
J Am Geriatr Soc ; 49(7): 934-40, 2001 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-11527485

RESUMO

OBJECTIVE: To assess the impact of cognitive impairment on mortality in older primary care patients after controlling for confounding effects of demographic and comorbid chronic conditions. DESIGN: Prospective cohort study. SETTING: Academic primary care group practice. PARTICIPANTS: Three thousand nine hundred and fifty-seven patients age 60 and older who completed the Short Portable Mental Status Questionnaire (SPMSQ) during routine office visits. MEASUREMENTS: Cognitive impairment measured at baseline using the SPMSQ, demographics, problem drinking, history of smoking, clinical data (including weight, cholesterol level, and serum albumin), and comorbid chronic conditions collected at baseline; survival time measured during the 5 to 7 years after baseline. RESULTS: Eight hundred and eighty-six patients (22.4%) died during the 5 to 7 years of follow-up. Cognitive impairment was categorized as having no impairment (84.3%), mild impairment (10.5%), and moderate-to-severe impairment (5.2%) based on SPMSQ score. Chi-square tests revealed that patients with moderate-to-severe impairment were significantly more likely to die compared with patients with mild impairment (40.8% vs 21.5%) and those with no impairment (40.8% vs 21.4%). No significant difference in crude mortality was found between patients with no impairment and those with mild impairment. After analyzing time to death using the Kaplan-Meier method, patients with moderate-to-severe cognitive impairment were at increased risk of death compared with those with no or mild impairment (Log-rank chi(2) = 55.5; P <.0001). Even in multivariable analyses using Cox proportional hazards to control for confounding factors, compared with those with no impairment, moderately-to-severely impaired patients had an increased risk of death, with a hazard ratio (HR) of 1.70. Increased risk of death was also associated with older age (HR = 1.03 for each year), a history of smoking (HR = 1.48), having a serum albumin level <3.5 g/L (HR = 1.29), and weighing less than 90% of the ideal body weight (HR = 1.98). Outpatient diagnoses associated with increased mortality risk were diabetes mellitus, coronary artery disease, congestive heart failure, cerebrovascular disease, cancer, anemia, and chronic obstructive pulmonary disease (HR range 1.36-1.67). Factors protective of mortality risk included female gender (HR = 0.67) and black race (HR = 0.73). CONCLUSIONS: Moderate-to-severe cognitive impairment is associated with an increased risk of mortality, even after controlling for confounding effects of demographic and clinical characteristics. Mild cognitive impairment is not associated with mortality risk, but a longer follow-up period may be necessary to identify this risk if it exists.


Assuntos
Idoso/estatística & dados numéricos , Transtornos Cognitivos/complicações , Transtornos Cognitivos/mortalidade , Medicina de Família e Comunidade/estatística & dados numéricos , Prática de Grupo/estatística & dados numéricos , Atenção Primária à Saúde/estatística & dados numéricos , Centros Médicos Acadêmicos , Transtornos Cognitivos/classificação , Transtornos Cognitivos/diagnóstico , Comorbidade , Fatores de Confusão Epidemiológicos , Feminino , Avaliação Geriátrica , Humanos , Indiana/epidemiologia , Masculino , Programas de Rastreamento , Entrevista Psiquiátrica Padronizada , Análise Multivariada , Modelos de Riscos Proporcionais , Estudos Prospectivos , Fatores de Risco , Índice de Gravidade de Doença , Inquéritos e Questionários , Análise de Sobrevida
4.
Med Care ; 39(8): 772-84, 2001 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-11468497

RESUMO

BACKGROUND: Two million older Americans suffer from depression annually. Depression causes more functional impairment than many other common medical conditions and older adults have the highest rate of suicide in the United States. Although many of these patients fail to seek or fail to receive care for depression, the majority will be seen in primary care for the treatment of other conditions. OBJECTIVE: To review the health services research on quality improvement for late life depression. METHODS: Qualitative literature review. RESULTS: During the past 30 years, multiple educational and quality improvement interventions have been designed and tested to improve the recognition and treatment of depression in primary care settings. The findings from this large body of health services research suggest that: (1) the outcome of major depression in the usual care of primary care is typically poor; this is particularly true of late life depression; (2) informational support provided to primary care physicians is necessary but insufficient to improve the outcomes of late life depression in primary care; achieving guideline-level therapy requires the substantial participation of an informed and motivated patient working in concert with a health care team and health care system designed to care for chronic conditions; (3) up to 30% of older primary care patients will fail to respond to excellent guideline-level therapy provided in primary care; and (4) the latest quality improvement efforts focus not only on the clinical skills of primary care physicians, but also on patient's self-care and on innovative strategies to improve the system of care. CONCLUSIONS: Late life depression is often a chronic disease and outcomes research demonstrates that quality improvement efforts that focus resources on improving systems of care and the active participation of patients offer the best evidence of improved patient outcomes.


Assuntos
Transtorno Depressivo/terapia , Serviços de Saúde para Idosos/normas , Atenção Primária à Saúde/normas , Garantia da Qualidade dos Cuidados de Saúde , Idoso , Transtorno Depressivo/diagnóstico , Humanos , Modelos Organizacionais , Guias de Prática Clínica como Assunto , Estados Unidos
5.
Med Care ; 39(8): 785-99, 2001 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-11468498

RESUMO

BACKGROUND: Late life depression can be successfully treated with antidepressant medications or psychotherapy, but few depressed older adults receive effective treatment. RESEARCH DESIGN: A randomized controlled trial of a disease management program for late life depression. SUBJECTS: Approximately 1,750 older adults with major depression or dysthymia are recruited from seven national study sites. INTERVENTION: Half of the subjects are randomly assigned to a collaborative care program where a depression clinical specialist supervised by a psychiatrist and a primary care expert supports the patient's regular primary care provider to treat depression. Intervention services are provided for 12 months using antidepressant medications and Problem Solving Treatment in Primary Care according to a stepped care protocol that varies intervention intensity according to clinical needs. The other half of the subjects are assigned to care as usual. EVALUATION: Subjects are independently assessed at baseline, 3 months, 6 months, 12 months, 18 months, and 24 months. The evaluation assesses the incremental cost-effectiveness of the intervention compared with care as usual. Specific outcomes examined include care for depression, depressive symptoms, health-related quality of life, satisfaction with depression care, health care costs, patient time costs, market and nonmarket productivity, and household income. CONCLUSIONS: The study blends methods from health services and clinical research in an effort to protect internal validity while maximizing the generalizability of results to diverse health care systems. We hope that this study will show the cost-effectiveness of a new model of care for late life depression that can be applied in a range of primary care settings.


Assuntos
Transtorno Depressivo/terapia , Gerenciamento Clínico , Serviços de Saúde para Idosos/normas , Atenção Primária à Saúde/normas , Idoso , Antidepressivos/uso terapêutico , Análise Custo-Benefício , Transtorno Distímico/terapia , Feminino , Serviços de Saúde para Idosos/economia , Humanos , Capacitação em Serviço , Masculino , Avaliação de Resultados em Cuidados de Saúde , Equipe de Assistência ao Paciente , Educação de Pacientes como Assunto , Atenção Primária à Saúde/economia , Design de Software , Estados Unidos
6.
J Am Geriatr Soc ; 49(11): 1525-9, 2001 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-11890593

RESUMO

OBJECTIVES: The effectiveness of percutaneous endoscopic gastrostomy (PEG) in older adults remains controversial. Although prior studies have examined the safety of PEG and its impact on nutrition, there are limited data on the economic costs. The purpose of this study is to describe the healthcare costs associated with PEG tube feeding over 1 year. DESIGN: Prospective cohort study. SETTING: Small community of approximately 60,000 residents served by two hospital systems. PARTICIPANTS: One hundred five (70%) of 150 patients age 60 and older receiving PEG over a 24-month period in the targeted community who permitted access to their medical records. MEASUREMENTS: Patients were interviewed at baseline and every 2 months for 1 year to obtain information on use of enteral formula, complication rates, and health services use. We obtained inpatient charge data for all hospitalizations and PEG procedures for 1 year. RESULTS: Censoring patients at death or 1 year post-PEG, the mean number of days of PEG tube feeding was 180 (range 5-365). The average cost for PEG tube feeding for this cohort of patients was $7,488 (median $3,691) in 1997 and 1998. The average daily cost of PEG tube feeding was $87.21 (median $33.50). The estimated cost of providing 1 year of feeding via PEG is $31,832 (median $12,227). The main components of this cost include the initial PEG procedure (29.4%), enteral formula (24.9%), and hospital charges for major complications (33.4%). CONCLUSIONS: Direct charges associated with PEG tube feeding over 1 year are conservatively estimated at $31,832; there was considerable variation in charges because of the cost of rare but costly major complications. Also, feeding patients via PEG resulted in cost shifts in terms of the primary payor. The economic cost of PEG tube feeding is another consideration in decision making for long-term enteral feeding among older adults.


Assuntos
Nutrição Enteral/economia , Gastroscopia/economia , Gastrostomia/economia , Custos de Cuidados de Saúde/estatística & dados numéricos , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Indiana , Assistência de Longa Duração/economia , Masculino , Pessoa de Meia-Idade
7.
J Neurosci Nurs ; 33(6): 292-5, 2001 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-11776710

RESUMO

This study examined reasons why patients discontinue the ketogenic diet. A total of 46 children placed on the ketogenic diet between November 1994 and August 1996 were followed prospectively. Reasons for discontinuing the diet prior to 6 months were analyzed. Nineteen (41%) children discontinued the diet for either medical or nonmedical reasons. Nonmedical reasons were caregiver issues and patients' unwillingness to follow the diet. Noncompliance was more common in older children. The ketogenic diet, while effective, is a very stringent diet. Nonmedical reasons for discontinuation are as common as the traditional medical reasons of lack of efficacy or complications.


Assuntos
Gorduras na Dieta/uso terapêutico , Epilepsia/dietoterapia , Cetonas/metabolismo , Cooperação do Paciente , Adolescente , Fatores Etários , Cuidadores , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Cetose/metabolismo , Masculino , Satisfação do Paciente , Estudos Prospectivos , Paladar , Resultado do Tratamento
8.
J Am Geriatr Soc ; 48(9): 1048-54, 2000 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-10983903

RESUMO

OBJECTIVE: Percutaneous endoscopic gastrostomy (PEG) has become the preferred method to provide enteral tube feeding to older adults who have difficulty eating, but the impact of PEG on patient outcomes is poorly understood. The objective of this study was to describe changes in nutrition, functional status, and health-related quality of life among older adults receiving PEG. DESIGN: A prospective cohort study. SETTING: A small community of approximately 60,000 residents served by two hospital systems. PARTICIPANTS: One hundred fifty patients aged 60 and older receiving PEG from one of the four gastroenterologists practicing in the targeted community. MEASUREMENTS: Patients were assessed at baseline and every 2 months for 1 year to obtain clinical characteristics, process of care data, physical and cognitive function, subjective health status, nutritional status, complications, and mortality. RESULTS: Over a 14-month period, 150 patients received PEG tubes in the targeted community; the mean age was 78.9. The most frequent indications for the PEG were stroke (40.7%), neurodegenerative disorders (34.7%), and cancer (13.3%). All measures of functional status, cognitive status, severity of illness, comorbidity, and quality of life demonstrated profound and life-threatening impairment; 30-day mortality was 22% and 1-year mortality was 50%. Among patients surviving 60 days or more, at least 70% had no significant improvement in functional, nutritional, or subjective health status. Serious complications were rare, but most patients experienced symptomatic problems that they attributed to the enteral tube feeding. CONCLUSIONS: PEG tube feeding in severely and chronically ill older adults can be accomplished safely. However, there are important patient burdens associated with the PEG and there was limited evidence that the procedure improves functional, nutritional, or subjective health status in this cohort of older adults. The issues raised in this descriptive study provide impetus for a randomized trial of PEG tube feeding compared with alternative methods of patient care for older adults with difficulty eating.


Assuntos
Atividades Cotidianas , Gastroscopia , Gastrostomia , Estado Nutricional , Qualidade de Vida , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Atitude Frente a Saúde , Nutrição Enteral/efeitos adversos , Nutrição Enteral/mortalidade , Nutrição Enteral/psicologia , Feminino , Gastroscopia/efeitos adversos , Gastroscopia/mortalidade , Gastroscopia/psicologia , Gastrostomia/efeitos adversos , Gastrostomia/mortalidade , Gastrostomia/psicologia , Avaliação Geriátrica , Humanos , Masculino , Pessoa de Meia-Idade , Avaliação de Processos e Resultados em Cuidados de Saúde , Estudos Prospectivos , Análise de Sobrevida , Resultado do Tratamento
9.
J Am Geriatr Soc ; 48(7): 760-8, 2000 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-10894314

RESUMO

OBJECTIVES: The amount of medication dispensed to older adults for the treatment of chronic disease must be balanced carefully. Insufficient medication supplies lead to inadequate treatment of chronic disease, whereas excessive supplies represent wasted resources and the potential for toxicity. We used an electronic medical record system to determine the distribution of medications supplied to older urban adults and to examine the correlations of these distributions with healthcare costs and use. DESIGN: A cross-sectional study using data acquired over 3 years (1994-1996). SETTING: A tax-supported urban public healthcare system consisting of a 300-bed hospital, an emergency department, and a network of community-based ambulatory care centers. PATIENTS: Patients were >60 years of age and had at least one prescription refill and at least two ambulatory visits or one hospitalization during the 3-year period. MEASUREMENTS: Focusing on 12 major categories of drugs used to treat chronic diseases, we determined the amounts and direct costs of these medications dispensed to older adult patients. Amounts of medications that were needed by patients to medicate themselves adequately were compared with the medication supply actually dispensed considering all sources of care (primary, emergency, and inpatient). We calculated the excess drug costs attributable to oversupply of medication (>120% of the amount needed) and the drug cost reduction caused by undersupply of medication (<80% of the amount needed). We also compared total healthcare use and costs for patients who had an oversupply, an undersupply, or an appropriate supply of their medications. RESULTS: The cohort comprised 4164 patients with a mean age of 71 +/- 7 (SD) who received a mean of 3 +/- 2 (SD) drugs for chronic conditions. There were 668 patients (16%) who received <80% of the supply needed, 1556 patients (37%) who received between 80 and 120% of the supply needed, and 1940 patients (47%) who received >120% of the supply needed. The total direct cost of targeted medications for 3 years was $1.96 million or, on average, $654,000 annually. During the 3-year period, patients receiving >120% of their needed medications had excess direct medication costs of $279,084 or $144 per patient, whereas patients receiving <80% of drugs needed had reduced medication costs of $423,438 or $634 per patient. Multivariable analyses revealed that both under- and over-supplies of medication were associated with a greater likelihood of emergency department visits and hospital admissions. CONCLUSIONS: More than one-half of the older adults in our study have under- or over-supplies of medications for the treatment of their chronic diseases. Such inappropriate supplies of medications are associated with healthcare utilization and costs.


Assuntos
Doença Crônica/economia , Custos de Medicamentos/estatística & dados numéricos , Serviços de Saúde para Idosos/economia , Preparações Farmacêuticas/provisão & distribuição , Saúde da População Urbana , Adulto , Idoso , Doença Crônica/tratamento farmacológico , Análise Custo-Benefício , Estudos Transversais , Feminino , Custos de Cuidados de Saúde , Humanos , Indiana , Masculino , Pessoa de Meia-Idade , Admissão do Paciente/economia , Cuidados de Saúde não Remunerados/economia
11.
Am J Med ; 107(5): 425-31, 1999 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-10569296

RESUMO

PURPOSE: Physical symptoms are responsible for substantial morbidity in outpatients. We assessed symptoms in patients admitted to a hospital to determine their frequency, persistence at discharge, and the relation between symptom outcome and satisfaction with care. METHODS: During a 12-month period, 2,126 hospitalized medical patients completed a study interview within 2 hours of admission. More than half (n = 1,168) of the patients were re-interviewed within 24 hours of discharge. We ascertained the presence and severity of 11 physical symptoms, as well as activities of daily living, mobility, mood, self-rated health, physiologic severity of illness, satisfaction with care, and length of stay. RESULTS: Symptoms were common at the time of hospital admission, particularly fatigue (80% of patients), dyspnea (60%), cough (51%), dizziness (51%), headache (47%), chest pain (46%), and nausea or vomiting (43%). Individual symptoms failed to resolve by hospital discharge approximately 25% to 50% of the time. The three most prominent predictors of persistence of symptoms were shorter length of stay, severity of the symptom on admission, and total symptom count. Patient satisfaction with care was associated with total symptom severity score at discharge and the degree of symptomatic improvement that had occurred during hospitalization. CONCLUSION: Because symptoms are common at discharge and associated with decreased satisfaction with care, asking about them would be a reasonable way to enhance patient-oriented care.


Assuntos
Pacientes Internados/estatística & dados numéricos , Avaliação de Resultados em Cuidados de Saúde , Alta do Paciente/estatística & dados numéricos , Satisfação do Paciente/estatística & dados numéricos , Hospitais com 300 a 499 Leitos , Hospitais de Ensino/normas , Hospitais Urbanos/normas , Humanos , Indiana , Razão de Chances , Assistência Centrada no Paciente , Índice de Gravidade de Doença
12.
J Am Geriatr Soc ; 47(9): 1105-9, 1999 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-10484254

RESUMO

OBJECTIVE: To describe clinical decision-making for percutaneous endoscopic gastrostomy from the perspective of patients, caregivers, and physicians. DESIGN: A prospective cohort study. SETTING AND PATIENTS: All patients aged 60 and older receiving percutaneous endoscopic gastrostomies in a defined community over a 16-month period. MAIN OUTCOMES MEASURES: Either patients or their surrogate decision-makers completed a semistructured face-to-face interview to map out the information gathering process, expectations, and discussants involved in the decision to proceed with gastrostomy feeding. Physicians completed a written questionnaire to determine their likelihood of recommending percutaneous endoscopic gastrostomy, their involvement in the decision-making and recommendation process, and sources of perceived pressure in the decision-making. RESULTS: We identified 100 patients who received percutaneous endoscopic gastrostomy during the study window and 82 primary care physicians who provided care in the defined community. The most common reasons for the procedure were stroke, neurologic disease, and cancer. Patients or their surrogate decision-makers reported multiple discussants, incomplete information, and considerable distress in arriving at the decision to proceed with artificial feeding. This distress was usually in the context of an acute and debilitating illness that often overshadowed the decision about artificial feeding. The decision for gastrostomy often appeared to be a "non-decision" in the sense that decision-makers perceived few alternatives. Physicians also reported considerable distress in arriving at recommendations to proceed with percutaneous endoscopic gastrostomy, including perceived pressures from families or other healthcare professionals. Physicians have clear patterns of triage for percutaneous endoscopic gastrostomy, but the assumptions underlying these patterns are not well supported by the medical literature. CONCLUSIONS: Patients, caregivers, and physicians are often compelled to make decisions about long-term enteral feeding under tragic circumstances and with incomplete information. Decision-makers typically do not perceive any acceptable alternatives. Because data on these patients' long-term functional outcomes are lacking, decision-makers appear to focus primarily on the short-term safety of the procedure and the potential for improved nutrition.


Assuntos
Tomada de Decisões , Nutrição Enteral , Gastrostomia , Serviços de Saúde para Idosos , Idoso , Cuidadores/psicologia , Redes Comunitárias , Nutrição Enteral/psicologia , Feminino , Gastrostomia/psicologia , Nível de Saúde , Humanos , Masculino , Pessoa de Meia-Idade , Pacientes/psicologia , Relações Médico-Paciente , Médicos/psicologia , Estudos Prospectivos , Medição de Risco , Inquéritos e Questionários , Incerteza
13.
Med Care ; 37(7): 662-70, 1999 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-10424637

RESUMO

BACKGROUND: Understanding older adults' volume and patterns of health service use is fundamental to efforts to improve the quality and efficiency of services. OBJECTIVE: To analyze the accuracy of older adults' self report of health services use and to determine the proportion of care obtained outside a defined urban academic health care system. RESEARCH DESIGN: Telephone survey of self-reports validated against data routinely archived in an electronic medical record system. SUBJECTS: Stratified random sample of 422 patients (> or = 60 years) who had contact with the health care system at least once in the previous 3 months. MEASURES: Self reports of hospitalizations, emergency room visits, physicians visits, extended care visits, and home care visits over the past 12 months, health status, physical activity, and sociodemographics factors. RESULTS: The sample population was more likely to report health services use and functional disability than was a community-based sample of older adults; 67% of the sample were women, 53.9% were African American, 71% were age 65 and over, 38.7% lived alone, and 24.6% reported poor financial resources. Based on data from the electronic medical record, 27.9% of the sample were hospitalized at least once in the prior 12 months, 54.6% had at least one emergency room visit, and the mean number of ambulatory visits was 8.1. Comparing self-report data to the electronic record data, 24.1% of older adults with a hospitalization in the prior 12 months failed to report the episode; 28.1% of those with an emergency room visit failed to report the episode as did 5.2% of those with an ambulatory care visit. The accuracy of the self reports of volume of these services were also substantially under reported. We were unable to identify any patient characteristics that were highly correlated with inaccuracy. We estimate that approximately 9.5% of health care costs are accrued outside this urban health care system. CONCLUSIONS: These older adults substantially under-report health services use, including hospital episodes over a 12-month period. Reliance on self-reported use data over the prior year to model patterns of health care use among older adults is not supported by these data.


Assuntos
Pesquisas sobre Atenção à Saúde/métodos , Serviços de Saúde/estatística & dados numéricos , Aceitação pelo Paciente de Cuidados de Saúde/estatística & dados numéricos , Inquéritos e Questionários , População Urbana/estatística & dados numéricos , Centros Médicos Acadêmicos/estatística & dados numéricos , Idoso , Área Programática de Saúde , Feminino , Avaliação Geriátrica , Custos de Cuidados de Saúde/estatística & dados numéricos , Serviços de Saúde/economia , Serviços de Saúde para Idosos/economia , Serviços de Saúde para Idosos/estatística & dados numéricos , Nível de Saúde , Humanos , Indiana , Modelos Logísticos , Masculino , Sistemas Computadorizados de Registros Médicos , Pessoa de Meia-Idade , Reprodutibilidade dos Testes , Autoavaliação (Psicologia)
14.
Am J Epidemiol ; 150(1): 37-44, 1999 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-10400551

RESUMO

Oxidative stress has been implicated both in the aging process and in the pathological changes associated with Alzheimer's disease. Antioxidants, which have been shown to reduce oxidative stress in vitro, may represent a set of potentially modifiable protective factors for poor memory, which is a major component of the dementing disorders. The authors investigated the association between serum antioxidant (vitamins E, C, A, carotenoids, selenium) levels and poor memory performance in an elderly, multiethnic sample of the United States. The sample consisted of 4,809 non-Hispanic White, non-Hispanic Black, and Mexican-American elderly who visited the Mobile Examination Center during the Third National Health and Nutrition Examination Survey, a national cross-sectional survey conducted from 1988 to 1994. Memory is assessed using delayed recall (six points from a story and three words) with poor memory being defined as a combined score less than 4. Decreasing serum levels of vitamin E per unit of cholesterol were consistently associated with increasing levels of poor memory after adjustment for age, education, income, vascular risk factors, and other trace elements and minerals. Serum levels of vitamins A and C, beta-carotene, and selenium were not associated with poor memory performance in this study.


Assuntos
Antioxidantes/metabolismo , Ácido Ascórbico/sangue , Negro ou Afro-Americano/estatística & dados numéricos , Carotenoides/sangue , Transtornos da Memória/sangue , Transtornos da Memória/etnologia , Americanos Mexicanos/estatística & dados numéricos , Selênio/sangue , Vitamina A/sangue , Vitamina E/sangue , População Branca/estatística & dados numéricos , Idoso , Idoso de 80 Anos ou mais , Envelhecimento/efeitos dos fármacos , Envelhecimento/fisiologia , Estudos Transversais , Feminino , Humanos , Masculino , Transtornos da Memória/diagnóstico , Transtornos da Memória/etiologia , Pessoa de Meia-Idade , Inquéritos Nutricionais , Fatores de Risco , Estados Unidos/epidemiologia
15.
J Clin Epidemiol ; 52(1): 65-71, 1999 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-9973075

RESUMO

Patient perceptions of their health are often inadequately captured and explored on hospital admission where physiologic and other objective measures are the focus of attention. Therefore, we conducted a prospective study to develop and validate measures of several domains of patient-reported health status at the time of admission to a general medicine inpatient service, and to determine the value of these new measures in predicting length of stay (LOS). Within 2 hours of the time that a decision to admit a patient was made, research assistants delivered a structured interview that captured patients' current symptoms, functional status, mood, and perceived health. Interviews were conducted between 8 a.m. and 11 p.m., 5 days per week from July 1996 through June 1997. During this time, there were 3621 unique patients admitted to the medicine service; 2672 (74%) of these patients were eligible for an interview. Eighty-eight percent of the 2672 eligible patients were interviewed. In addition to the patient-reported measures captured through the structured interview, the acute physiology score (APS) of the APACHE II was calculated for all subjects. The internal consistency (i.e., Cronbach's alpha) of the scales was 0.76 or greater and concurrent validity (i.e., correlation) of the patient-reported measures with the APS was 0.01 to 0.13. Overall perceived health was correlated 0.20 to 0.45 with symptoms and functional status, and was correlated 0.07 with the APS. The patient-reported measures performed comparably to the APS in predicting LOS (R-square = 0.08). When the patient-reported measures and the APS were included in the same model, the R-square was 0.14. These analyses suggest that patient-reported measures of health and function on admission hold validity, and that responses to as few as 15 questions can provide data that may help to explain differences in length of a hospital stay.


Assuntos
Nível de Saúde , Tempo de Internação/estatística & dados numéricos , Admissão do Paciente , Inquéritos e Questionários/normas , APACHE , Atividades Cotidianas , Afeto , Viés , Feminino , Humanos , Indiana , Masculino , Pessoa de Meia-Idade , Valor Preditivo dos Testes , Estudos Prospectivos , Análise de Regressão , Reprodutibilidade dos Testes
16.
J Palliat Med ; 2(4): 403-9, 1999.
Artigo em Inglês | MEDLINE | ID: mdl-15859781

RESUMO

PURPOSE: Psychiatric morbidity is common in cancer patients toward the end of life. In this study, we demonstrate the use of an electronic patient record system to identify patients with advanced cancer, and then analyze practice patterns regarding the use of antidepressants. PATIENTS AND METHODS: Using electronic patient records from January 1986 to December 1996, we identified 17,476 patients with possible cancer. Patients were identified by virtue of having any one of eight markers. We used an iterative process to modify the specificity of these markers, and an advanced cancer cohort was assembled consisting of 1185 patients. RESULTS: A random sample of 200 written medical records were reviewed, of which 157 records (78.5%) were retrieved. Extracted information was reviewed by an oncologist, and patients were classified as follows: (1) no evidence of cancer; (2) evidence of cancer with an expected survival of less than or equal to 24 months; or (3) evidence of cancer with an expected survival of more than 24 months. Overall, 86% of the advanced cancer sample assembled from electronic records was correctly classified as advanced cancer by the review of the written records. Overall, 16% of all 1185 patients with advanced cancer were exposed to at least one antidepressant, with 3% of patients exposed to a selective serotonin-reuptake inhibitor, 10% exposed to a tricyclic antidepressant at a dose of greater than 25 mg, and 4% exposed to a low dose of a tricyclic antidepressant. CONCLUSION: The electronic patient record can be used to assemble an advanced cancer cohort for the purpose of studying palliative care practice patterns. Antidepressants are seldom part of the palliative management of this population.

17.
J Gen Intern Med ; 13(11): 746-52, 1998 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-9824520

RESUMO

OBJECTIVE: To determine whether depressive symptoms measured at baseline are associated with mortality and to describe the course of depressive symptoms and their relation to physical decline in patients over a 6-year period. DESIGN: Prospective cohort study conducted from 1990 through 1996. SETTING: Urban academic primary care group practice. PATIENTS: A cohort of 3,767 patients aged 60 years and older screened for depressive symptoms during routine office visits using the Centers for Epidemiologic Studies Depression Scale (CES-D) participated in the mortality study. A subsample of 300 patients with CES-D scores 16 or above and a subsample of 100 patients with CES-D scores less than 16 participated in the study of the course of depressive symptoms and physical decline. MEASUREMENTS AND MAIN RESULTS: Mortality by December 1995 was measured for all screened patients; reinterviewed patients completed the CES-D and the Sickness Impact Profile (SIP). The mean follow-up period was 45 months (+/- SD 12.2 months); 561 (14.9%) of the patients died by December 1995. In proportional hazards models, age, gender, race, history of smoking, serum albumin value, and an ideal body weight in the lowest 10% were significant correlates of time to death, but the baseline CES-D was not. Patients with depressive symptoms had significantly worse physical and psychosocial functioning scores on the SIP than did patients without depressive symptoms. Using the generalized estimating equation method, the strongest predictor of the current CES-D score was the patient's prior CES-D score. However, worsening physical functioning score on the SIP was also independently correlated with worse CES-D scores p < or = .001). CONCLUSIONS: Symptoms of depression were not associated with mortality in this cohort of older adults. However, patients with depressive symptoms reported greater functional impairment than did those without depressive symptoms. Moreover, decline in physical functioning was independently correlated with a concurrent increase in depressive symptoms.


Assuntos
Idoso/psicologia , Depressão/mortalidade , Pessoas com Deficiência/psicologia , Atividades Cotidianas , Idoso de 80 Anos ou mais , Estudos de Coortes , Depressão/complicações , Depressão/diagnóstico , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Modelos de Riscos Proporcionais , Estudos Prospectivos , Sensibilidade e Especificidade , Perfil de Impacto da Doença , Análise de Sobrevida
18.
J Am Geriatr Soc ; 46(11): 1371-7, 1998 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-9809758

RESUMO

BACKGROUND: Urban academic medical centers provide care for large populations of vulnerable older adults. These patients often suffer a disproportionate share of chronic illnesses, disabilities, and social stressors that may increase health care costs. OBJECTIVE: To describe the distribution and content of total healthcare costs accrued over a 4-year period by a community of older adults cared for in an urban academic healthcare system and to describe high-cost patients and utilization patterns. DESIGN: A cohort study. SETTING: A tax-supported public healthcare system consisting of a 450-bed hospital and seven community-based ambulatory care centers. PATIENTS: 12,581 patients aged 60 years and older who had at least two ambulatory visits and/or one hospitalization within the healthcare system from 1993 through 1995. MEASUREMENTS: Patient demographic and clinical characteristics, hospital and ambulatory utilization rates, and all healthcare costs accrued from 1993 through 1996 were determined. Costs were estimated from the perspective of the healthcare system using cost to charge ratios. MAIN RESULTS: The mean patient age was 70 years, 60% were women, 44% were Black, and 83% were covered by Medicare and/or Medicaid. Nearly 25% of patients were obese, 15.8% had a history of smoking, and 15.5% had evidence of malnutrition. The mean number of ambulatory visits per year was 4.3 (+/-7.2), and 38.1% of patients had been hospitalized one or more times. Within the 4-year window, 24.1% of patients had missed five or more appointments with their primary care physicians, 32.7% of patients had five or more unscheduled clinic visits, and 12.5% had five or more emergency room visits. Total health care costs for 4 years for this cohort of older adults was $125.2 million dollars, with per capita annual mean costs of $3893. Expenditures associated with hospitalizations accounted for 63.6% of healthcare costs. Total inpatient and outpatient costs for the 38% of patients hospitalized at least once accounted for 85.3% of all health care expenditures. Patients who died in the hospital did not accrue significantly greater costs than patients who died out of the hospital. Simulations of a random 5% adverse selection of high-cost patients among two capitated systems resulted in cost shifts of $11.1 million. Recorded smoking history, obesity, and low serum albumin were significantly associated with excess costs. CONCLUSIONS: Healthcare costs are concentrated in a significant minority of older adults. Costs accrued in conjunction with hospital stays dominate healthcare expenditures for this cohort of older adults. However, most older adults (83%) have one or fewer hospital episodes in a 4-year period. Although patients who died accrued greater healthcare costs, these costs were not higher when the death occurred in the hospital. Self-care behaviors are an important target for interventions to reduce costs.


Assuntos
Centros Médicos Acadêmicos/economia , Custos de Cuidados de Saúde/estatística & dados numéricos , Serviços de Saúde para Idosos/economia , Serviços Urbanos de Saúde/economia , Centros Médicos Acadêmicos/estatística & dados numéricos , Centros Médicos Acadêmicos/tendências , Idoso , Estudos de Coortes , Centros Comunitários de Saúde/economia , Centros Comunitários de Saúde/estatística & dados numéricos , Centros Comunitários de Saúde/tendências , Feminino , Custos de Cuidados de Saúde/tendências , Serviços de Saúde para Idosos/estatística & dados numéricos , Serviços de Saúde para Idosos/tendências , Custos Hospitalares/estatística & dados numéricos , Custos Hospitalares/tendências , Humanos , Indiana , Masculino , Pessoa de Meia-Idade , Análise de Regressão , Serviços Urbanos de Saúde/estatística & dados numéricos , Serviços Urbanos de Saúde/tendências
19.
Arch Pediatr Adolesc Med ; 152(7): 651-8, 1998 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-9667536

RESUMO

BACKGROUND: Although managed care favors use of alternative settings in an attempt to avoid hospitalization, uncertainty about possible deterioration creates concern about their safety. OBJECTIVE: To derive preliminary estimates for the risk of adverse outcome in children hospitalized with acute illness who met criteria for admission to potentially less-expensive, alternative settings (eg, short-stay unit, home nursing). DESIGN: Description of hospitalization outcomes for a community-wide childhood population. SETTING AND POPULATION: All 11591 hospitalizations for residents of Monroe County (Rochester), New York, aged 1 month to 18 years in 1991 and 1992. MEASUREMENTS: To identify potential adverse outcomes in alternative settings (numerator estimate), hospital medical records for admissions to regular inpatient units were examined. To ascertain deterioration among these admissions, detailed record reviews were conducted if the child died or was transferred to another hospital or to a critical care unit. To estimate the total number of admissions eligible for care in alternative settings (denominator estimate), hospital discharge files were analyzed. RESULTS: Deterioration was found in 83 medical admissions. Of these 83, major chronic problems (n=53) or severe illness at presentation (n=27) precluded alternative setting eligibility, leaving only 3 in whom alternative setting care might have been considered. The total number of admissions eligible for alternative setting care was estimated between 1661 (restrictive criteria) and 3322 (inclusive criteria) for the 2-year observation period. Based on these observations, best- and worst-case estimates for the risk of deterioration in candidates for care in alternative settings were 0.6 and 1.8 per 1000, respectively. For the 3 children for whom alternative setting care might have been considered, the shortest period from first indication of deterioration to arrival in the critical care unit was 3.0 hours. CONCLUSIONS: These preliminary estimates suggest that alternative settings may be safe for the care of many children currently hospitalized. A randomized clinical trial to evaluate directly the potential benefits and harms of alternative setting care should be considered.


Assuntos
Instituições de Assistência Ambulatorial , Progressão da Doença , Hospitalização , Avaliação de Resultados em Cuidados de Saúde , Adolescente , Criança , Pré-Escolar , Interpretação Estatística de Dados , Feminino , Serviços de Assistência Domiciliar , Humanos , Lactente , Masculino , Risco
20.
Ann Intern Med ; 127(12): 1124-5, 1997 Dec 15.
Artigo em Inglês | MEDLINE | ID: mdl-9412317
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