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1.
J Anaesthesiol Clin Pharmacol ; 32(4): 446-452, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-28096573

RESUMO

BACKGROUND AND AIMS: Emergence time, or the duration between incision closure and extubation, is costly nonoperative time. Efforts to improve operating room efficiency and identify trainee progress make such time intervals of interest. We sought to calculate the incidence of prolonged emergence (i.e., >15 min) for patients under the care of clinical anesthesia (CA) residents. We also sought to identify factors from resident training, medical history, anesthetic use, and anesthesia staffing, which affect emergence. MATERIAL AND METHODS: In this single-center, historical cohort study, perioperative information management systems provided data for surgical cases under resident care at a tertiary care center in the United States from 2006 to 2008. Using multiple logistic regression, the effects of variables on emergence was analyzed. RESULTS: Of 7687 cases under the care of 27 residents, the incidence of prolonged emergence was 13.9%. Emergence prolongation decreased by month in training for 1st-year (CA-1) residents (r2 = 0.7, P < 0.001), but not for CA-2 and CA-3 residents. Mean patient emergence time differed among 27 residents (P < 0.01 for 58.4% or 205/351 paired comparisons). In a model restricted to 1st-year residents, patient male gender, American Society of Anesthesiologists (ASA) physical status >II, emergency surgical case, operative duration ≥2 h, and paralytic agent use were associated with higher frequency of prolonged emergence, while sevoflurane or desflurane use was associated with lower frequency. Attending anesthesiologist handoff was not associated with longer emergence. CONCLUSION: Incidence of prolonged emergence from general anesthesia differed significantly among trainees, by resident training duration, and for patients with ASA >II.

2.
Ear Hear ; 36(2): 249-60, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25259669

RESUMO

OBJECTIVES: The goal was to measure the magnitude of cochlear responses to sound in pediatric cochlear implant recipients at the time of implantation and to correlate this magnitude with subsequent speech perception outcomes. DESIGN: A longitudinal cohort study of pediatric cochlear implant recipients was undertaken. Intraoperative electrocochleographic (ECoG) recordings were obtained from the round window in response to a frequency series at 90 dB nHL in 77 children totaling 89 ears (12 were second side surgeries) just before device insertion. The increase in intraoperative time was approximately 10 min. An ECoG "total response" metric was derived from the summed magnitudes of significant responses to the first, second, and third harmonics across a series of frequencies. A subset of these children reached at least 9 months of implant use and were old enough for the phonetically balanced kindergarten (PB-k) word test to be administered (n = 26 subjects and 28 ears). PB-k scores were compared to the ECoG total response and other biologic and audiologic variables using univariate and multiple linear regression analyses. RESULTS: ECoG responses were measurable in almost all ears (87 of 89). The range of ECoG total response covered about 60 dB (from ~0.05 to 50 µV). Analyzing individual ECoG recordings in bilaterally implanted children revealed poor concordance between the measured response in the first versus second ear implanted (r = 0.21; p = 0.13; n = 12). In a univariate linear regression, the ECoG total response was significantly correlated with PB-k scores in the subset of 26 subjects who were able to be tested and accounted for 32% of the variance (p = 0.002, n = 28). Preoperative pure-tone average (PTA) accounted for slightly more of the variance (r = 0.37, p = 0.001). However, ECoG total response and PTA were significantly but only weakly correlated (r = 0.14, p = 0.001). Other significant predictors of speech performance included hearing stability (stable versus progressive) and age at testing (22 and 16% of the variance, respectively). In multivariate analyses with these four factors, the ECoG accounted for the most weight (ß = 0.36), followed by PTA (ß = 0.26). In a hierarchical multiple regression analysis, the most parsimonious models that best predicted speech perception outcomes included three variables: ECoG total response, and any two of preoperative PTA, age at testing, or hearing stability. The various three factor models each predicted approximately 50% of the variance in word scores. Without the ECoG total response, the other three factors predicted 36% of variance. CONCLUSIONS: Intraoperative round window ECoG recordings are reliably and easily obtained in pediatric cochlear implant recipients. The ECoG total response is significantly correlated with speech perception outcomes in pediatric implant recipients and can account for a comparable or greater proportion of variance in speech perception than other bio-audiologic factors. Intraoperative recordings can potentially provide useful prognostic information about acquisition of open set speech perception in implanted children.


Assuntos
Perda Auditiva/reabilitação , Janela da Cóclea/fisiopatologia , Percepção da Fala , Adolescente , Audiometria de Resposta Evocada , Criança , Pré-Escolar , Implante Coclear/métodos , Estudos de Coortes , Feminino , Perda Auditiva/fisiopatologia , Humanos , Lactente , Cuidados Intraoperatórios , Modelos Lineares , Estudos Longitudinais , Masculino , Análise Multivariada , Prognóstico , Estudos Prospectivos , Resultado do Tratamento
3.
Otol Neurotol ; 35(8): 1451-7, 2014 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-24892369

RESUMO

OBJECTIVE: Electrophysiologic responses to acoustic stimuli are present in nearly all cochlear implant recipients when measured at the round window (RW). Intracochlear recording sites might provide an even larger signal and improve the sensitivity and the potential clinical utility of electrocochleography (ECoG). Thus, the goal of this study is to compare RW to intracochlear recording sites and to determine if such recordings can be used to monitor cochlear function during insertion of a cochlear implant. METHODS: Intraoperative ECoG recordings were obtained in subjects receiving a cochlear implant from the RW and from just inside scala tympani (n = 26). Stimuli were tones at high levels (80-100 dB HL). Further recordings were obtained during insertions of a temporary lateral cochlear wall electrode (n = 8). Response magnitudes were determined as the sum of the first and second harmonics amplitudes. RESULTS: All subjects had measurable extracochlear responses at the RW. Twenty cases (78%) showed a larger intracochlear response, compared with three (11%) that had a smaller response and three that were unchanged. On average, signal amplitudes increased with increasing electrode insertion depths, with the largest increase between 15 and 20 mm from the RW. CONCLUSION: ECoG to acoustic stimuli via an intracochlear electrode is feasible in standard cochlear implant recipients. The increased signal can improve the speed and efficiency of data collection. The growth of response magnitudes with deeper intrascalar electrode positions could be explained by closer proximity or favorable geometry with respect to residual apical signal generators. Reductions in magnitude may represent unfavorable geometry or cochlear trauma.


Assuntos
Audiometria de Resposta Evocada/métodos , Implante Coclear/métodos , Monitorização Neurofisiológica Intraoperatória/métodos , Estimulação Acústica/métodos , Adulto , Cóclea/cirurgia , Implantes Cocleares , Feminino , Humanos , Masculino
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