RESUMO
Tuberculosis (TB) is a life-threatening infectious disease with a high world incidence. However, TB with oral expression is considered rare. The importance of recognising this entity lies in its early diagnosis and treatment, as it can be easily confused with neoplastic or traumatic ulcers. We present a case of a primary TB located in the hard palate and gingiva in an 88-year-old woman.
Assuntos
Doenças da Gengiva/diagnóstico , Palato Duro/patologia , Tuberculose Bucal/diagnóstico , Idoso de 80 Anos ou mais , Antituberculosos/uso terapêutico , Feminino , Doenças da Gengiva/tratamento farmacológico , Doenças da Gengiva/patologia , Humanos , Tuberculose Bucal/tratamento farmacológico , Tuberculose Bucal/patologiaRESUMO
A case of bilateral carcinoma in situ of Wharton's duct after chronic sialadenitis is reported. The patient, a 54-year-old man, complained of recurrent pain and swelling in the left lower submandibular region. Computed tomography showed large stones in the hilar area of both submandibular glands. The patient underwent bilateral submandibular excision. Histologic and immunohistochemical examination revealed squamous metaplasia with areas of carcinoma in situ in both right and left ducts adjacent to the calculus. To the best of our knowledge, this is the first case report in the literature describing an association between obstructive sialadenitis and carcinoma in situ of Wharton's duct. We discuss etiologic factors and chronic inflammation as a possible cause of malignancy.
Assuntos
Carcinoma in Situ/imunologia , Inflamação/imunologia , Lesões Pré-Cancerosas/imunologia , Cálculos dos Ductos Salivares/cirurgia , Ductos Salivares/patologia , Sialadenite/imunologia , Neoplasias da Glândula Submandibular/imunologia , Carcinoma in Situ/diagnóstico , Carcinoma in Situ/cirurgia , Transformação Celular Neoplásica , Humanos , Inflamação/patologia , Masculino , Pessoa de Meia-Idade , Lesões Pré-Cancerosas/patologia , Ductos Salivares/imunologia , Ductos Salivares/cirurgia , Sialadenite/patologia , Neoplasias da Glândula Submandibular/diagnóstico , Neoplasias da Glândula Submandibular/cirurgia , Resultado do TratamentoRESUMO
INTRODUCTION: Oncocytic carcinoma is a rare proliferation of cytomorphologically malignant oncocytes mainly found in glandular tissue, accounting for 0.5% of all epithelial salivary gland malignancies and 0.18% of all epithelial salivary gland tumors. CASE PRESENTATION: We report a case of oncocytic carcinoma arising in the parotid gland of a 65-year-old Caucasian man. Our patient initially underwent left superficial parotidectomy, including the removal of the mass. A close follow-up was made, and four years after first surgery cervical lymph node metastases were confirmed. Therefore, a complete parotidectomy and radical neck dissections were performed. There were no complications and no sign of recurrence after six months of follow-up. CONCLUSION: Oncocytic carcinoma is an extremely rare malignancy in the salivary glands. Prophylactic neck dissection may be indicated for tumors larger than 2 cm in diameter (our patient's tumor was 2.5 cm at its greatest diameter). The clinical course of our patient, with the appearance of cervical lymph node metastases after four years of follow-up, supports this approach. Further investigation of the prognosis and correct treatment of patients with oncocytic carcinoma are required as more cases are reported.
RESUMO
Un varón de 85 años ingresó en nuestro hospital para valoración de lumbalgia invalidante de 2 meses de evolución. Tenía antecedentes de lumbalgia recidivante, hepatopatía crónica por el virus C de la hepatitis y diabetes mellitus tipo 2. Se observó por técnicas de imagen afección vertebral y discal, y en el cultivo del material aspirado a nivel discal creció Enterococcus faecalis, que también fue demostrado en hemocultivos, con idénticas características fenotípicas. Tras 6 semanas de tratamiento parenteral, corsé y fisioterapia experimentó progresiva mejoría, y se lo siguió ambulatoriamente. Se comenta la rareza de E. faecalis como agente etiológico de la espondilodiscitis, lo que condiciona actitudes terapéuticas basadas en las orientaciones microbiológicas aplicadas a otras formas más frecuentes de etiología piógena y según antibiograma
An 85-year-old man was admitted to our hospital for evaluation of disabling low back pain with onset 2 months previously. The patient had a history of recurrent lower back pain, hepatitis C virus infection and type 2 diabetes. Imaging techniques showed vertebral and discal involvement. Culture of the aspirated discal specimen revealed Enterococcus faecalis, which was also found in blood cultures, with the same phenotypic characters. After 6 weeks of parenteral antibiotics, bracing and physical therapy, the patient progressively improved and was followed-up on an outpatient basis. E. faecalis is a rare cause of spondylodiscitis, which may lead to this etiological agent being overlooked in favor of other more frequent etiologic agents