RESUMO
In recent years, there has been an increase in the incidence of insect-borne diseases. Topically applied insect repellents are used to prevent these infectious diseases, but concerns of skin permeability and rapid evaporation rates have made way for alternative preventative methods. Encapsulation of insect repellents in polymeric materials allows for nonskin contact methods of repellent delivery with extended-release profiles without the need for reapplication. Poly(ethylene terephthalate) (PET) is widely used in textiles as well as food packaging and other single-use applications. This short product lifespan makes PET a major environmental pollutant; thus, recycling of PET is of great interest and utility. We report on the fabrication and evaluation of recycled PET microfibers containing N,N-diethyl-meta-toluamide (DEET) and picaridin and the first evaluation of dual repellent loading (DEET/picaridin) via electrospinning. The electrospun microfibers displayed a repellent retention up to 97% within the polymer network upon processing. Release profiles were characterized by isothermal thermogravimetric analysis (TGA). Hansen solubility parameters correlated release profiles with the chemical affinity between PET and the repellent substrate. Insect repellency was assessed against live mosquitoes using a novel bioassay method. Repellency was observed to be as high as 100% for over 1 week and 80% for over 3 weeks. Our method allows for long-lasting repellency with the potential for large-scale textile manufacturing.
