RESUMO
Two cases of gonadal dysgenesis and stigmata of Turner's syndrome with ring chromosome X are described. Their features support the idea that ring chromosome X should be considered as a deletion in the genetic sense, affecting both the gonadal and statural determinants. Without knowing the cytogenetic findings, these patients are usually labeled as having Turner's syndrome. Furthermore, endocrine data and histologic examination of the gonads are indistinguishable from those of individuals with 45,X or 46XX gonadal dysgenesis.
Assuntos
Amenorreia/genética , Aberrações Cromossômicas , Disgenesia Gonadal/genética , Transtornos do Crescimento/genética , Cromossomos em Anel , Cromossomo X , Adolescente , Adulto , Deleção Cromossômica , Feminino , Humanos , MosaicismoRESUMO
A case of successful gonadotropins ovulation induction and donor artificial insemination (AID) followed by a complication of hydatidiform mole is presented. A review of the published papers related to this topic are commented. The organization of a world registry of AID depending on the World Health Organization is encouraged.
