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1.
Rev Chilena Infectol ; 29(4): 382-7, 2012 Aug.
Artigo em Espanhol | MEDLINE | ID: mdl-23096536

RESUMO

In order to understand the clinical and epidemiological aspects of infection with the AH1N1 influenza virus in Chile, a prospective study in the city of San Felipe was undertaken. It analyses the trends in consultations for respiratory causes in three primary care centers and hospital discharges by comparing data from years 2008 and 2009 until epidemiological week 37.It also includes a study of cases of ILI / SARI (influenza like disease/severe acute respiratory disease) in which viruses were detected by direct immunofluorescence (DIF) of nasopharyngeal aspirates and by real-time polymerase chain reaction in the case of influenza A (H1N1) 2009. A household survey was conducted in those cases with confirmed A (H1N1) infection, to identify contacts and history related to influenza virus transmission. The results indicate that the behavior of the pandemic was similar to that observed in the rest of the country, with an increase in emergency room visits for ILI. The most affected age group was from 5 to 14 years (26.5 per thousand inhabitants) and the least affected 60 years or older (1.2 per thousand). A 2.78% of the cases corresponded to SARI and the fatality rate was 0.11%.


Assuntos
Vírus da Influenza A Subtipo H1N1 , Influenza Humana/epidemiologia , Síndrome Respiratória Aguda Grave/epidemiologia , Adolescente , Adulto , Distribuição por Idade , Criança , Pré-Escolar , Chile/epidemiologia , Busca de Comunicante , Serviço Hospitalar de Emergência , Feminino , Humanos , Lactente , Recém-Nascido , Influenza Humana/diagnóstico , Masculino , Pessoa de Meia-Idade , Pandemias , Estudos Prospectivos , Reação em Cadeia da Polimerase em Tempo Real , Síndrome Respiratória Aguda Grave/diagnóstico , Adulto Jovem
2.
Rev. chil. infectol ; 29(4): 382-387, ago. 2012. graf, tab
Artigo em Espanhol | LILACS | ID: lil-649824

RESUMO

In order to understand the clinical and epidemiological aspects of infection with the AH1N1 influenza virus in Chile, a prospective study in the city of San Felipe was undertaken. It analyses the trends in consultations for respiratory causes in three primary care centers and hospital discharges by comparing data from years 2008 and 2009 until epidemiological week 37.It also includes a study of cases of ILI / SARI (influenza like disease/severe acute respiratory disease) in which viruses were detected by direct immunofluorescence (DIF) of nasopharyngeal aspirates and by real-time polymerase chain reaction in the case of influenza A (H1N1) 2009. A household survey was conducted in those cases with confirmed A (H1N1) infection, to identify contacts and history related to influenza virus transmission. The results indicate that the behavior of the pandemic was similar to that observed in the rest of the country, with an increase in emergency room visits for ILI. The most affected age group was from 5 to 14 years (26.5 per thousand inhabitants) and the least affected 60 years or older (1.2 per thousand). A 2.78% of the cases corresponded to SARI and the fatality rate was 0.11%.


Con el objetivo de conocer los aspectos clínicos y epidemiológicos de la infección por el virus A (H1N1) en Chile, se realizó un estudio prospectivo en la ciudad de San Felipe, lugar donde el brote de influenza se inició tardíamente en relación a otras ciudades del país. Se analizó la tendencia en las consultas por causa respiratorias en tres centros de atención primaria y egresos hospitalarios comparando los años 2008 y 2009 hasta la semana epidemiológica 37, y se realizó un estudio prospectivo de casos de enfermedad tipo influenza/infección respiratoria aguda grave (ETI/IRAG), tomando muestras mediante aspirado nasofaríngeo para detección de virus respiratorios por in-munofluorescencia directa (IFD) e identificación de virus influenza A (H1N1) 2009 por reacción de polimerasa en cadena en tiempo real (RPC-TR). En los pacientes confirmados se hizo una encuesta en visita domiciliaria para identificación de contactos y antecedentes relacionados con la transmisión de la influenza. Los resultados indican que el comportamiento de la pandemia fue similar a lo observado en el resto del país, con aumento de consulta principalmente en los servicios de urgencia; el grupo de edad más afectado fue el de 5 a 14 años (26,5 por mil habitantes), el menos afectado el grupo mayor de 60 años (1,2 por mil habitantes). Un 2,78% de los casos correspondió a IRAG y la tasa de letalidad fue de 0,11%.


Assuntos
Adolescente , Adulto , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Pessoa de Meia-Idade , Adulto Jovem , Vírus da Influenza A Subtipo H1N1 , Influenza Humana/epidemiologia , Síndrome Respiratória Aguda Grave/epidemiologia , Distribuição por Idade , Busca de Comunicante , Chile/epidemiologia , Serviço Hospitalar de Emergência , Influenza Humana/diagnóstico , Pandemias , Estudos Prospectivos , Reação em Cadeia da Polimerase em Tempo Real , Síndrome Respiratória Aguda Grave/diagnóstico
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