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J Cosmet Dermatol ; 16(4): 520-526, 2017 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-28786550

RESUMO

BACKGROUND: Brittle nail syndrome is a common problem among women and refers to nails that exhibit surface roughness, raggedness, and peeling. AIM: The goal of this study was to investigate whether daily oral supplementation with collagen peptides alleviates the symptoms of brittle nails and improves nail growth rate. METHODS: In this open-label, single-center trial, 25 participants took 2.5 g of specific bioactive collagen peptides (BCP, VERISOL® ) once daily for 24 weeks followed by a 4-week off-therapy period. Nail growth rate and the frequency of cracked and/or chipped nails as well as an evaluation of symptoms and global clinical improvement score of brittle nails were assessed by a physician during treatment and 4 weeks after discontinuation. RESULTS: Bioactive collagen peptides treatment promoted an increase of 12% nail growth rate and a decrease of 42% in the frequency of broken nails. Additionally, 64% of participants achieved a global clinical improvement in brittle nails, and 88% of participants experienced an improvement 4 weeks post-treatment. The majority of participants (80%) agreed that the use of BCP improved their nails' appearance, and were completely satisfied with the performance of the treatment. CONCLUSIONS: This study demonstrated that the daily ingestion of BCP increased nail growth and improved brittle nails in conjunction with a notable decrease in the frequency of broken nails.


Assuntos
Colágeno/uso terapêutico , Doenças da Unha/tratamento farmacológico , Unhas/crescimento & desenvolvimento , Peptídeos/uso terapêutico , Administração Oral , Adulto , Colágeno/administração & dosagem , Suplementos Nutricionais , Feminino , Humanos , Pessoa de Meia-Idade , Unhas/efeitos dos fármacos , Satisfação do Paciente , Peptídeos/administração & dosagem
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