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Transpl Infect Dis ; 4(4): 207-11, 2002 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-12535264

RESUMO

Transplant recipients receive a number of immunosuppressive medications that result in an increased risk of infection, including infections with microbes that are normally not pathogenic. We describe a patient with end-stage renal disease who underwent kidney transplantation. Six months postoperatively, he presented with a lesion on his ankle, multiple thigh nodules, and right testicular pain. Biopsy of the ankle lesion demonstrated Pseudallescheria boydii (Scedosporium apiospermum), a common environmental fungus. Following orchiectomy, multiple fungal elements were found that were initially described as Aspergillus species, but later identified as P. boydii. In addition, multiple brain abscesses were found on magnetic resonance imaging. Despite treatment with multiple antifungal medications, the patient died of cardiac dysrhythmia. Current diagnostic and therapeutic alternatives for P. boydii are reviewed.


Assuntos
Transplante de Rim/efeitos adversos , Micetoma/etiologia , Micetoma/patologia , Pseudallescheria/patogenicidade , Antifúngicos/uso terapêutico , Humanos , Imunossupressores/uso terapêutico , Itraconazol/uso terapêutico , Masculino , Pessoa de Meia-Idade , Micetoma/tratamento farmacológico , Micetoma/microbiologia , Pseudallescheria/crescimento & desenvolvimento
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