RESUMO
Although they have proven effectiveness, radiofrequency and microwave ablation techniques have a high rate of partial responses. Diagnostic studies that anticipate the changes in morphology are essential for earlier detection of residual viable tumor tissue or local recurrences to identify patients who will benefit from a new treatment. Our study has determined the diagnostic yield of PET/CT studies at baseline and follow-up and adequate time between them and the ablation intervention. Seven patients with single tumor lesion with a total of 8 ablations were included. CT and PET/CT studies were performed at baseline and follow-up after ablation. Average times between PET studies at baseline and follow-up and the ablative therapy were 1.8 and 3.4 months, respectively. Mean scores in metabolic activities of the PET at baseline and follow-up were 7.6 and 4.3g/ml of SUVmax, respectively. The Dual Time Point technique helped to identify viable tissue after ablation in 3 cases. Follow-up PET/CT studies have conditioned the various treatment strategies adopted by clinical oncologists. The high yield of the PET/CT study including the Dual Time Point technique may be considered as a study replacement of initial and follow-up Contrast-Enhanced CT before and after treatment with RFA and AMO, this achieving considerable reduction in the exposure to high radiation levels. We propose conducting the first PET/CT follow-up study at 3 months of the RFA and AMO.
Assuntos
Carcinoma Pulmonar de Células não Pequenas/diagnóstico por imagem , Neoplasias Pulmonares/diagnóstico por imagem , Imagem Multimodal , Recidiva Local de Neoplasia/diagnóstico por imagem , Tomografia por Emissão de Pósitrons , Tomografia Computadorizada por Raios X , Adenocarcinoma/diagnóstico por imagem , Adenocarcinoma/metabolismo , Adenocarcinoma/patologia , Adenocarcinoma/cirurgia , Carcinoma Pulmonar de Células não Pequenas/metabolismo , Carcinoma Pulmonar de Células não Pequenas/patologia , Carcinoma Pulmonar de Células não Pequenas/cirurgia , Carcinoma de Células Escamosas/diagnóstico por imagem , Carcinoma de Células Escamosas/metabolismo , Carcinoma de Células Escamosas/patologia , Carcinoma de Células Escamosas/cirurgia , Ablação por Cateter , Eletrocoagulação , Radioisótopos de Flúor , Fluordesoxiglucose F18 , Seguimentos , Humanos , Neoplasias Pulmonares/metabolismo , Neoplasias Pulmonares/patologia , Neoplasias Pulmonares/cirurgia , Micro-Ondas/uso terapêutico , Neoplasia Residual/diagnóstico por imagem , Cuidados Paliativos , Cuidados Pós-Operatórios , Estudos Prospectivos , Compostos Radiofarmacêuticos , Resultado do TratamentoRESUMO
We present an 84-year-old woman with hyperthyroidism caused by an ectopic intrathoracic thyroid that was removed by sternotomy. Ectopic intrathoracic thyroid, also called primary intrathoracic goitre, is a rare presentation of thyroid disease and comprises about 1% of all mediastinal masses. Its coexistence with hyperthyroidism is extremely uncommon. Its removal usually requires thoracotomy or sternotomy.
Assuntos
Bócio Subesternal/complicações , Hipertireoidismo/etiologia , Idoso de 80 Anos ou mais , Carcinoma/diagnóstico , Carcinoma/secundário , Diagnóstico Diferencial , Erros de Diagnóstico , Feminino , Bócio Subesternal/diagnóstico por imagem , Humanos , Neoplasias Pulmonares/diagnóstico , Neoplasias Pulmonares/secundário , Pneumonia/complicações , Pneumonia/diagnóstico por imagem , Cintilografia , Compostos Radiofarmacêuticos , Pertecnetato Tc 99m de Sódio , Neoplasias da Glândula Tireoide/diagnóstico , Neoplasias da Glândula Tireoide/secundário , Tomografia Computadorizada por Raios XRESUMO
Se presenta el caso de una paciente de 84 años con hipertiroidismo por tiroides ectópico intratorácico que fue tratado quirúrgicamente. El tiroides ectópico intratorácico o bocio intratorácico primario es una presentación rara y comprende el 1% de todas las masas mediastínicas. La coexistencia con hipertiroidismo es extremadamente infrecuente. Su resección generalmente requiere una toracotomía o esternotomía (AU)
We present an 84-year-old woman with hyperthyroidism caused by an ectopic intrathoracic thyroid that was removed by sternotomy. Ectopic intrathoracic thyroid, also called primary intrathoracic goitre, is a rare presentation of thyroid disease and comprises about 1% of all mediastinal masses. Its coexistence with hyperthyroidism is extremely uncommon. Its removal usually requires thoracotomy or sternotomy (AU)
Assuntos
Humanos , Feminino , Idoso de 80 Anos ou mais , Bócio Subesternal/diagnóstico , Hipertireoidismo/diagnóstico , Toracotomia , Neoplasias do Mediastino/diagnóstico , Esterno/cirurgiaRESUMO
A total of 44 patients with a range of ages between 34 and 72 were studied by immunoscintigraphy. They have surgical treatment for colon and rectum carcinomas. The immunoradiotracer used was a cocktail of F(ab')2 monoclonal-antibodies anti-CEA and CA 19.9. Planar images were obtained 4th, 6th, and 10th days postinjection. In some cases we used digital subtraction of image. Both CEA and CA 19.9 tumor markers were measured in patients serum. The method shows a global high sensitivity (88%), and specificity (92%).
