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1.
Actas urol. esp ; 46(10): 640-645, dic. 2022.
Artigo em Espanhol | IBECS | ID: ibc-212791

RESUMO

Introducción: El estado de alarma debido a la COVID-19 revolucionó la actividad asistencial y quirúrgica. Dentro de la enfermedad urológica, aquellas consideradas «demorables» como la andrológica y la reconstructiva sufrieron un retraso considerable en su atención. Material y métodos: En mayo de 2020, tras haber superado casi la primera ola de la pandemia y en pleno estado de alarma, se envió una encuesta con 24 ítems a 120 urólogos integrados en los Grupos de Cirugía Reconstructiva Urológica y Andrología de la Asociación Española de Urología (AEU) para conocer la repercusión asistencial sobre la actividad clínica y quirúrgica en ambas subespecialidades. Resultados: Se alcanzó una tasa de respuesta del 75,8% con 91 encuestas recibidas. Previo al estado de alarma, el 49,5% disponía de uno a 2 quirófanos semanales, el 71,4% afrontaba una lista de espera quirúrgica de entre 3 y 12 meses, y el 39,6% atendía entre 20 y 40 pacientes semanales en consulta. Durante el estado de alarma, el 95,6% recibió directrices sobre cirugías a realizar, priorizando la cirugía urgente y la oncológica. En el 85,7% de los centros no se realizó ninguna cirugía andrológica ni reconstructiva. Alrededor del 50% de las consultas no fueron presenciales, recurriendo a la telemedicina (teléfono o e-mail) en la mayoría de los casos. Conclusiones: Las repercusiones de la pandemia sobre las enfermedades andrológicas y las candidatas a cirugía reconstructiva fueron muy importantes. Tras casi 2 años del inicio de la pandemia, aún queda por determinar el verdadero impacto final en nuestro sistema sanitario (AU)


Introduction: In Spain the state of alarm secondary to COVID-19 dramatically changed the medical and surgical assistance activity of other pathologies. Regarding urological pathologies, those considered as «non-urgent» (andrology and reconstructive surgery) were postponed or even unattended. Material and methods: In May 2020, once the first COVID-19 wave was almost over and still in the state of alarm, a 24-item survey was sent to 120 urologists from the Andrology Group and the Urologic Reconstructive Surgery Group of the Spanish Urological Association (AEU). Its aim was to determine the impact on clinical and surgical practice in both subspecialties. Results: We observed a response rate of 75.8% with 91 answered surveys. Before the state of alarm, 49.5% of urologists had 1-2 weekly surgical sessions available, surgical waiting list was 3-12 months for the 71.4%, and 39.6% attended between 20-40 patients weekly in office. During the state of alarm, 95.6% were given any kind of surgical guidelines, prioritizing emergency and oncologic pathologies. In the 85.7% of the hospitals neither andrology nor reconstructive surgeries were performed. In office, around 50% of patients were attended not on-site, most of them through telemedicine (phone calls and e-mails). Conclusions The negative pandemic implications in relation to the andrology and reconstructive surgery pathologies were truly important. After almost 2 years from the start of the pandemic, the true final impact on our health system has yet to be determined (AU)


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Pesquisas sobre Atenção à Saúde , Infecções por Coronavirus , Pneumonia Viral , Pandemias , Procedimentos de Cirurgia Plástica/estatística & dados numéricos , Unidade Hospitalar de Urologia/estatística & dados numéricos , Prioridades em Saúde , Espanha
2.
Actas Urol Esp (Engl Ed) ; 46(10): 640-645, 2022 12.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-36216766

RESUMO

INTRODUCTION: In Spain the state of alarm secondary to COVID-19 dramatically changed the medical and surgical assistance activity of other pathologies. Regarding urological pathologies, those considered as "non-urgent" (andrology and reconstructive surgery) were postponed or even unattended. MATERIAL AND METHODS: In May 2020, once the first COVID-19 wave was almost over and still in the state of alarm, a 24-item survey was sent to 120 urologists from the Andrology Group and the Urologic Reconstructive Surgery Group of the Spanish Urological Association (AEU). Its aim was to determine the impact on clinical and surgical practice in both subspecialties. RESULTS: We observed a response rate of 75.8% with 91 answered surveys. Before the state of alarm, 49.5% of urologists had 1-2 weekly surgical sessions available, surgical waiting list was 3-12 months for the 71.4%, and 39.6% attended between 20-40 patients weekly in office. During the state of alarm, 95.6% were given any kind of surgical guidelines, prioritizing emergency and oncologic pathologies. In the 85.7% of the hospitals neither andrology nor reconstructive surgeries were performed. In office, around 50% of patients were attended not on-site, most of them through telemedicine (phone calls and e-mails). CONCLUSIONS: The negative pandemic implications in relation to the andrology and reconstructive surgery pathologies were truly important. After almost 2 years from the start of the pandemic, the true final impact on our health system has yet to be determined.


Assuntos
COVID-19 , Humanos , COVID-19/epidemiologia , Pandemias , Espanha/epidemiologia
3.
Actas Urol Esp ; 46(10): 640-645, 2022 Dec.
Artigo em Espanhol | MEDLINE | ID: mdl-35765673

RESUMO

Introduction: In Spain the state of alarm secondary to COVID-19 dramatically changed the medical and surgical assistance activity of other pathologies. Regarding urological pathologies, those considered as «non-urgent¼ (andrology and reconstructive surgery) were postponed or even unattended. Material and methods: In May 2020, once the first COVID-19 wave was almost over and still in the state of alarm, a 24-item survey was sent to 120 urologists from the Andrology Group and the Urologic Reconstructive Surgery Group of the Spanish Urological Association (AEU). Its aim was to determine the impact on clinical and surgical practice in both subspecialties. Results: We observed a response rate of 75.8% with 91 answered surveys. Before the state of alarm, 49.5% of urologists had 1-2 weekly surgical sessions available, surgical waiting list was 3-12 months for the 71.4%, and 39.6% attended between 20-40 patients weekly in office. During the state of alarm, 95.6% were given any kind of surgical guidelines, prioritizing emergency and oncologic pathologies. In the 85.7% of the hospitals neither andrology nor reconstructive surgeries were performed. In office, around 50% of patients were attended not on-site, most of them through telemedicine (phone calls and e-mails). Conclusions: The negative pandemic implications in relation to the andrology and reconstructive surgery pathologies were truly important. After almost 2 years from the start of the pandemic, the true final impact on our health system has yet to be determined.

4.
Actas urol. esp ; 46(1): 49-56, ene.-feb. 2022. tab
Artigo em Espanhol | IBECS | ID: ibc-203535

RESUMO

Introducción Las estenosis de anastomosis ureteroileal son complicaciones frecuentes en conductos ileales y neovejigas ortotópicas. Analizamos su incidencia en función del tipo de derivación urinaria y del abordaje quirúrgico (abierto, laparoscópico o robótico). Describimos su manejo y los resultados obtenidos.Material y métodos Estudio retrospectivo descriptivo durante 6 años en pacientes con derivación urinaria empleando íleon (conducto ileal o neovejiga ileal). Se recogen datos demográficos, comorbilidades, datos quirúrgicos (abordaje, complicaciones) y resultados. Seguimiento mínimo de un año. Comparación entre grupos, mediante test de la chi al cuadrado en variables dicotómicas. Variables cuantitativas comparadas empleando la prueba de la t Student para grupos independientes o la prueba de Mann-Whitney. Consideramos significación estadística p<0,05.Resultados Incluimos a 182 pacientes (84% varones y 16% mujeres). Edad media 68 años. Abordaje de cistectomía: laparoscópica (67/37%), robótica (63/35%), abierta (43/24%). Tipo de derivación: conducto ileal (138/76%) y neovejiga ileal ortotópica (44/24%). Tipo de reimplante: Bricker (108/59%) y Wallace (47/26%). Estenosis de anastomosis ureteroileal (50/27%): bilateral (26), izquierda (16) y derecha (8). Estenosis según abordaje de cistectomía: laparoscópica (23/46%), robótica (16/32%), abierta (9/18%). Tratamiento de estenosis (33/18%): reimplante ureteroileal (13), nefrostomía permanente (13), dilatación endoscópica (4), nefroureterectomía (2), endoureterotomía (1). Abordaje del reimplante: laparoscópico (5/38%), robótico (6/46%) y abierto (2/15%). Resultados tras reimplantes: reestenosis (0/0%), reintervención (3/23%), estenosis ureteroileal contralateral posterior (1/8%).ConclusiónEl tipo de abordaje empleado en la cistectomía no parece influir en la aparición de estenosis ureteroileales. Abordajes laparoscópicos y robóticos permiten su reparación con resultados


Introduction Ureteroileal anastomosis stricture is a frequent complication after radical cystectomy and ileal conduit or orthotopic neobladder formation. We analyze their incidence based on the technique for urinary diversion and on the surgical approach (open, laparoscopic or robot-assisted). Stricture management is described, along with surgical outcomes.Material and methodsDescriptive retrospective study over 6 years in patients who underwent urinary diversion using ileum (ileal conduit or orthotopic neobladder). Demographic data, comorbidities, surgical approach, complications, and outcomes were collected. Minimum follow-up of 1 year. Comparison between groups using Chi-square test for dichotomous variables. Quantitative variables were compared using the Student's t test for independent groups or Mann-Whitney test. Statistical significance if P<.05.Results The study included 182 patients (84% males and 16% females). Mean age 68 years. Cystectomy approach: laparoscopic (67/37%), robot-assisted (63/35%), open (43/24%). Urinary diversion: ileal conduit (138/76%) and orthotopic ileal neobladder (44/24%). Ureteric reimplantation technique: Bricker (108/59%) and Wallace (47/26%). Ureteroileal anastomosis strictures (50/27%): bilateral (26), left (16) and right (8). Strictures according to cystectomy approach: laparoscopic (23/46%), robot-assisted (16/32%), open (9/18%). Treatment of strictures (33/18%): ureteric reimplantation (13), indwelling nephrostomy (13), endoscopic dilatation (4), nephroureterectomy (2), endoureterotomy (1). Ureteroileal reimplantation approach: laparoscopic (5/38%), robot-assisted (6/46%), open (2/15%). Outcomes after reimplantation: restenosis (0/0%), reintervention (3/23%), contralateral ureteroileal stricture (1/8%).Conclusion Surgical approach in cystectomy does not influence future development of ureteroileal strictures. Laparoscopic and robot-assisted ureteroileal reimplantation achieves high success rates (AU)


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Idoso , Procedimentos Cirúrgicos Robóticos , Derivação Urinária/efeitos adversos , Anastomose Cirúrgica , Constrição Patológica , Estudos Retrospectivos , Atenção Terciária à Saúde , Laparoscopia
5.
Actas Urol Esp (Engl Ed) ; 46(1): 49-56, 2022.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-34838493

RESUMO

INTRODUCTION: Ureteroileal anastomosis stricture is a frequent complication after radical cystectomy and ileal conduit or orthotopic neobladder formation. We analyze their incidence based on the technique for urinary diversion and on the surgical approach (open, laparoscopic or robot-assisted). Stricture management is described, along with surgical outcomes. MATERIAL AND METHODS: Descriptive retrospective study over 6 years in patients who underwent urinary diversion using ileum (ileal conduit or orthotopic neobladder). Demographic data, comorbidities, surgical approach, complications, and outcomes were collected. Minimum follow-up of 1 year. Comparison between groups using Chi-square test for dichotomous variables. Quantitative variables were compared using the Student's t-test for independent groups or Mann-Whitney test. Statistical significance if P < .05. RESULTS: The study included 182 patients (84% males and 16% females). Mean age 68 years. Cystectomy approach: laparoscopic (67/37%), robot-assisted (63/35%), open (43/24%). Urinary diversion: ileal conduit (138/76%) and orthotopic ileal neobladder (44/24%). Uretericre implantation technique: Bricker (108/59%) and Wallace (47/26%). Ureteroileal anastomosis strictures (50/27%): bilateral (26), left (16) and right (8). Strictures according to cystectomy approach: laparoscopic (23/46%), robot-assisted (16/32%), open (9/18%). Treatment of strictures (33/18%): ureteric reimplantation (13), indwelling nephrostomy (13), endoscopic dilatation (4), nephroureterectomy (2), endoureterotomy (1). Ureteroileal reimplantation approach: laparoscopic (5/38%), robot-assisted (6/46%), open (2/15%). Outcomes after reimplantation: restenosis (0/0%), reintervention (3/23%), contralateral ureteroileal stricture (1/8%). CONCLUSION: Surgical approach in cystectomy does not influence future development of ureteroileal strictures. Laparoscopic and robot-assisted ureteroileal reimplantation achieves high success rates.


Assuntos
Laparoscopia , Procedimentos Cirúrgicos Robóticos , Robótica , Derivação Urinária , Idoso , Anastomose Cirúrgica/efeitos adversos , Constrição Patológica , Feminino , Humanos , Incidência , Masculino , Estudos Retrospectivos , Procedimentos Cirúrgicos Robóticos/efeitos adversos , Centros de Atenção Terciária , Derivação Urinária/efeitos adversos
6.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-34332809

RESUMO

INTRODUCTION: Ureteroileal anastomosis stricture is a frequent complication after radical cystectomy and ileal conduit or orthotopic neobladder formation. We analyze their incidence based on the technique for urinary diversion and on the surgical approach (open, laparoscopic or robot-assisted). Stricture management is described, along with surgical outcomes. MATERIAL AND METHODS: Descriptive retrospective study over 6 years in patients who underwent urinary diversion using ileum (ileal conduit or orthotopic neobladder). Demographic data, comorbidities, surgical approach, complications, and outcomes were collected. Minimum follow-up of 1 year. Comparison between groups using Chi-square test for dichotomous variables. Quantitative variables were compared using the Student's t test for independent groups or Mann-Whitney test. Statistical significance if P<.05. RESULTS: The study included 182 patients (84% males and 16% females). Mean age 68 years. Cystectomy approach: laparoscopic (67/37%), robot-assisted (63/35%), open (43/24%). Urinary diversion: ileal conduit (138/76%) and orthotopic ileal neobladder (44/24%). Ureteric reimplantation technique: Bricker (108/59%) and Wallace (47/26%). Ureteroileal anastomosis strictures (50/27%): bilateral (26), left (16) and right (8). Strictures according to cystectomy approach: laparoscopic (23/46%), robot-assisted (16/32%), open (9/18%). Treatment of strictures (33/18%): ureteric reimplantation (13), indwelling nephrostomy (13), endoscopic dilatation (4), nephroureterectomy (2), endoureterotomy (1). Ureteroileal reimplantation approach: laparoscopic (5/38%), robot-assisted (6/46%), open (2/15%). Outcomes after reimplantation: restenosis (0/0%), reintervention (3/23%), contralateral ureteroileal stricture (1/8%). CONCLUSION: Surgical approach in cystectomy does not influence future development of ureteroileal strictures. Laparoscopic and robot-assisted ureteroileal reimplantation achieves high success rates.

7.
Actas urol. esp ; 45(2): 116-123, mar. 2021. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-201616

RESUMO

INTRODUCCIÓN: Durante la pandemia COVID-19, la actividad nacional de trasplante se ha visto reducida por la sobrecarga del sistema sanitario y la preocupación por la seguridad de los pacientes en esta situación. El objetivo de nuestro trabajo es exponer la actividad de trasplante renal en Cantabria durante el estado de alarma, así como valorar la seguridad del programa de trasplante. MATERIAL Y MÉTODOS: Estudio retrospectivo de los trasplantes renales realizados en nuestro Centro desde el inicio del estado de alarma hasta el inicio del desconfinamiento en Cantabria. Análisis descriptivo de los datos demográficos de receptores y sus donantes, datos intraoperatorios y resultados postoperatorios. Análisis comparativo con los datos del mismo periodo de 2017-2019, mediante los estadísticos χ2 para variables categóricas, T-Student y U de Mann-Whitney en caso de variables cuantitativas de distribución normal y no normal, respectivamente. RESULTADOS: Se realizaron 15 trasplantes renales en el periodo descrito. El 7,5% de pacientes presentaron función renal retrasada (FRR); el 26,6% mostró datos de rechazo agudo; ningún paciente presentó enfermedad por COVID-19. En el análisis comparativo, es llamativo el aumento del número de trasplantes frente a periodos anteriores (15 vs. 5,6), a expensas de donantes de fuera de Cantabria (93,3%). No encontramos diferencias estadísticamente significativas en cuanto a tiempo de isquemia fría (p = 0,77), FRR (p = 0,73), necesidad de diálisis (p = 0,54), o aparición de complicaciones posquirúrgicas (p = 0,61). CONCLUSIONES: La evolución de la pandemia en nuestra región y la adopción de medidas de protección rigurosas han permitido reiniciar el programa de trasplante renal de una forma temprana y segura, aumentando el número de trasplantes realizados frente a años anteriores y manteniendo unos resultados postoperatorios tempranos comparables


INTRODUCTION: During the COVID-19 pandemic, the national transplant activity has been reduced due to the overload of the health system and concern for patient safety in this situation. The aim of our work is to expose the activity of kidney transplantation in Cantabria during the state of alarm, as well as to assess the safety of the transplantation program. MATERIAL AND METHODS: Retrospective study of kidney transplants performed in our Center from the beginning of the state of alarm until the beginning of the lockdown easing in Cantabria. Descriptive analysis of the demographic data of recipients and their donors, intraoperative data and postoperative outcomes. Comparative analysis with the data of the same period in 2017-2019, by means of the χ2 for categorical variables, Student's T and Mann-Whitney U tests in case of quantitative variables of normal and non-normal distribution, respectively. RESULTS: Fifteen kidney transplants were performed in the period described. Delayed renal function (DRF) was seen in 7.5% of patients, and 26.6% showed data of acute rejection; no patient presented COVID-19 disease. Comparative analysis showed a remarkable increase in the number of transplants in comparison with previous periods (15 vs 5.6), at the expense of donors from outside Cantabria (93.3%). We found no statistically significant differences in terms of cold ischemia time (p = 0.77), DRF (p = 0.73), need for dialysis (p = 0.54), or appearance of post-surgical complications (p = 0.61). CONCLUSIONS: The evolution of the pandemic in our region, and the adoption of strict protective measures has allowed the early and safe resumption of the renal transplantation program, increasing the number of transplants performed compared to previous years and maintaining comparable early post-operative results


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Idoso , Transplante de Rim/estatística & dados numéricos , Infecções por Coronavirus , Pneumonia Viral , Estudos Retrospectivos , Pandemias , Betacoronavirus , Fatores de Risco , Resultado do Tratamento , Segurança do Paciente , Espanha , Hospitalização/estatística & dados numéricos
8.
Actas Urol Esp (Engl Ed) ; 45(2): 116-123, 2021 Mar.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-33213957

RESUMO

INTRODUCTION: During the COVID-19 pandemic, the national transplant activity has been reduced due to the overload of the health system and concern for patient safety in this situation. The aim of our work is to expose the activity of kidney transplantation in Cantabria during the state of alarm, as well as to assess the safety of the transplantation program. MATERIAL AND METHODS: Retrospective study of kidney transplants performed in our Center from the beginning of the state of alarm until the beginning of the lockdown easing in Cantabria. Descriptive analysis of the demographic data of recipients and their donors, intraoperative data and postoperative outcomes. Comparative analysis with the data of the same period in 2017-2019, by means of the χ2 for categorical variables, Student's T and Mann-Whitney U tests in case of quantitative variables of normal and non-normal distribution, respectively. RESULTS: Fifteen kidney transplants were performed in the period described. Delayed renal function (DRF) was seen in 7.5% of patients, and 26.6% showed data of acute rejection; no patient presented COVID-19 disease. Comparative analysis showed a remarkable increase in the number of transplants in comparison with previous periods (15 vs 5.6), at the expense of donors from outside Cantabria (93.3%). We found no statistically significant differences in terms of cold ischemia time (p=0.77), DRF (p=0.73), need for dialysis (p=0.54), or appearance of post-surgical complications (p=0.61). CONCLUSIONS: The evolution of the pandemic in our region, and the adoption of strict protective measures has allowed the early and safe resumption of the renal transplantation program, increasing the number of transplants performed compared to previous years and maintaining comparable early post-operative results.


Assuntos
COVID-19 , Transplante de Rim , Pandemias , Adulto , Soro Antilinfocitário/uso terapêutico , COVID-19/epidemiologia , COVID-19/prevenção & controle , Isquemia Fria , Comorbidade , Diabetes Mellitus/epidemiologia , Suscetibilidade a Doenças , Feminino , Rejeição de Enxerto/prevenção & controle , Rejeição de Enxerto/terapia , Humanos , Hipertensão/epidemiologia , Imunossupressores/efeitos adversos , Imunossupressores/uso terapêutico , Nefropatias/cirurgia , Transplante de Rim/métodos , Transplante de Rim/estatística & dados numéricos , Necrose Tubular Aguda/induzido quimicamente , Necrose Tubular Aguda/prevenção & controle , Masculino , Pessoa de Meia-Idade , Obesidade/epidemiologia , Transplante de Pâncreas/estatística & dados numéricos , Plasmaferese , Terapia de Substituição Renal , Reoperação/estatística & dados numéricos , Estudos Retrospectivos , Risco , Espanha/epidemiologia , Resultado do Tratamento
9.
Actas urol. esp ; 44(2): 71-77, mar. 2020. tab
Artigo em Espanhol | IBECS | ID: ibc-192839

RESUMO

INTRODUCCIÓN Y OBJETIVO: Conocer el manejo de la estenosis uretral (EU) es importante para evaluar la calidad asistencial y planificar acciones formativas. Planteamos investigar prácticas diagnósticas y terapéuticas de los urólogos en España para el manejo de EU anterior del varón adulto. Materiales y MÉTODOS: Realizamos un cuestionario on line de 23 preguntas entre los miembros de la Asociación Española de Urología (AEU). Evaluamos datos demográficos y referentes a la evaluación y tratamiento de EU. Fueron enviadas por correo electrónico 1.737 invitaciones, con un 21,7% de respuestas. La recogida prospectiva fue durante 2016. El análisis descriptivo y las comparaciones univariantes se efectuaron empleando el test de Chi cuadrado. Hubo significación estadística cuando p ≤ 0,05. RESULTADOS: Participaron principalmente urólogos de hospitales terciarios y universitarios. El 63,2% tratan ≥10 pacientes/año con EU. La uretrografía retrógrada es la prueba diagnóstica más empleada, seguida de la uroflujometría (UF). La uretrotomía interna bajo visión directa (UIVD) es el tratamiento más común. El 84,4% limita la UIVD a EU ≤ 1,5 cm. El 62,3% realiza ≤ 5 uretroplastias/año. El 75,7% hace uretroplastias anastomóticas y el 68,9% emplea injertos. Existe preferencia por injertar dorsalmente. El 23,9% emplea técnicas non-transecting. La UF es la prueba preferida para el seguimiento. El 88,4% refiere que son necesarias unidades de referencia. En centros terciarios realizan cuestionarios Patient Reported Outcome Measure más frecuentemente que en secundarios. Urólogos con alto volumen de cirugías usan más comúnmente técnicas non-transecting y eligen la uretroplastia como opción de primera línea. CONCLUSIONES: La EU anterior del varón en España es tratada por gran cantidad de urólogos, principalmente mediante endoscopia. La uretrografía retrógrada se prefiere para el diagnóstico y la UF para el seguimiento. Un elevado porcentaje de urólogos realiza uretroplastia, mayoritariamente anastomótica, pero con bajo número de casos


INTRODUCTION AND OBJECTIVE: Assessment of urethral stricture (US) management seems important to evaluate the quality of attention and plan educational INTERVENTIONS: We aim to investigate the practice patterns on diagnostic and therapeutic approaches to adult male anterior US among urologists in Spain. MATERIALS AND METHODS: 23-question on-line survey conducted among all members of AEU (Spanish Urological Association). Demography data and practices on evaluation and treatment of US were included.1737 invitation letters sent by email, with 21.7% response rate. Data were prospectively collected during 2016. Descriptive analysis and univariate comparisons conducted using X2 test. Statistical significance considered when P ≤ .05. RESULTS: Responders were mainly from Tertiary and Teaching University Hospitals.63.2% treated ≥ 10 patients/year with US. Retrograde urethrogram (RUG) was the commonest diagnostic tool followed by uroflowmetry (UF), and internal urethrotomy under direct vision (DVIU) the most frequent treatment.84.4% limited DVIU for US ≤ 1.5 cm.62.3% performed ≤ 5 urethroplasties/year. Anastomotic urethroplasties were performed by 75.7% and graft repairs by 68.9%. Dorsal grafting was preferred rather than ventral. Non-transecting techniques were used by 23.9%. UF was the most common follow-up tool.88.4% felt that referral units were required. Tertiary hospitals used Patient Reported Outcome Measure (PROM) questionnaires more frequently than secondary centres. High-volume urologists were more likely to use non-transecting techniques and to choose urethroplasty as first choice procedure. CONCLUSIONS: Male anterior US in Spain are treated by many urologists, mainly using endoscopic procedures. RUG is preferred for diagnosis, and UF for follow-up. A high percentage of urologists perform urethroplasties, mainly anastomotic repairs, but in low volumen


Assuntos
Humanos , Masculino , Adulto , Pessoa de Meia-Idade , Pesquisas sobre Atenção à Saúde , Padrões de Prática Médica , Estreitamento Uretral/cirurgia , Espanha
10.
Actas Urol Esp (Engl Ed) ; 44(2): 71-77, 2020 Mar.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-32005523

RESUMO

INTRODUCTION AND OBJECTIVE: Assessment of urethral stricture (US) management seems important to evaluate the quality of attention and plan educational interventions. We aim to investigate the practice patterns on diagnostic and therapeutic approaches to adult male anterior US among urologists in Spain. MATERIALS AND METHODS: 23-question on-line survey conducted among all members of AEU (Spanish Urological Association). Demography data and practices on evaluation and treatment of US were included. 1737 invitation letters sent by email, with 21.7% response rate. Data were prospectively collected during 2016. Descriptive analysis and univariate comparisons conducted using X2 test. Statistical significance considered when P≤.05. RESULTS: Responders were mainly from Tertiary and Teaching University Hospitals. 63.2% treated≥10 patients/year with US. Retrograde urethrogram (RUG) was the commonest diagnostic tool followed by uroflowmetry (UF), and internal urethrotomy under direct vision (DVIU) the most frequent treatment. 84.4% limited DVIU for US≤1.5cm. 62.3% performed≤5 urethroplasties/year. Anastomotic urethroplasties were performed by 75.7% and graft repairs by 68.9%. Dorsal grafting was preferred rather than ventral. Non-transecting techniques were used by 23.9%. UF was the most common follow-up tool. 88.4% felt that referral units were required. Tertiary hospitals used Patient Reported Outcome Measure (PROM) questionnaires more frequently than secondary centres. High-volume urologists were more likely to use non-transecting techniques and to choose urethroplasty as first choice procedure. CONCLUSIONS: Male anterior US in Spain are treated by many urologists, mainly using endoscopic procedures. RUG is preferred for diagnosis, and UF for follow-up. A high percentage of urologists perform urethroplasties, mainly anastomotic repairs, but in low volume.


Assuntos
Pesquisas sobre Atenção à Saúde , Padrões de Prática Médica , Estreitamento Uretral/diagnóstico , Estreitamento Uretral/cirurgia , Urologia , Adulto , Humanos , Masculino , Pessoa de Meia-Idade , Espanha
11.
Actas urol. esp ; 44: 0-0, 2020. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-194904

RESUMO

INTRODUCCIÓN: Durante la pandemia COVID-19, la actividad nacional de trasplante se ha visto reducida por la sobrecarga del sistema sanitario y la preocupación por la seguridad de los pacientes en esta situación. El objetivo de nuestro trabajo es exponer la actividad de trasplante renal en Cantabria durante el estado de alarma, así como valorar la seguridad del programa de trasplante. MATERIAL Y MÉTODOS: Estudio retrospectivo de los trasplantes renales realizados en nuestro Centro desde el inicio del estado de alarma hasta el inicio del desconfinamiento en Cantabria. Análisis descriptivo de los datos demográficos de receptores y sus donantes, datos intraoperatorios y resultados postoperatorios. Análisis comparativo con los datos del mismo periodo de 2017-2019, mediante los estadísticos χ2 para variables categóricas, T-Student y U de Mann-Whitney en caso de variables cuantitativas de distribución normal y no normal, respectivamente. RESULTADOS: Se realizaron 15 trasplantes renales en el periodo descrito. El 7,5% de pacientes presentaron función renal retrasada (FRR); el 26,6% mostró datos de rechazo agudo; ningún paciente presentó enfermedad por COVID-19. En el análisis comparativo, es llamativo el aumento del número de trasplantes frente a periodos anteriores (15 vs. 5,6), a expensas de donantes de fuera de Cantabria (93,3%). No encontramos diferencias estadísticamente significativas en cuanto a tiempo de isquemia fría (p = 0,77), FRR (p = 0,73), necesidad de diálisis (p = 0,54), o aparición de complicaciones posquirúrgicas (p = 0,61). CONCLUSIONES: La evolución de la pandemia en nuestra región y la adopción de medidas de protección rigurosas han permitido reiniciar el programa de trasplante renal de una forma temprana y segura, aumentando el número de trasplantes realizados frente a años anteriores y manteniendo unos resultados postoperatorios tempranos comparables


INTRODUCTION: During the COVID-19 pandemic, the national transplant activity has been reduced due to the overload of the health system and concern for patient safety in this situation. The aim of our work is to expose the activity of kidney transplantation in Cantabria during the state of alarm, as well as to assess the safety of the transplantation program. MATERIAL AND METHODS: Retrospective study of kidney transplants performed in our Center from the beginning of the state of alarm until the beginning of the lockdown easing in Cantabria. Descriptive analysis of the demographic data of recipients and their donors, intraoperative data and postoperative outcomes. Comparative analysis with the data of the same period in 2017-2019, by means of the χ2 for categorical variables, Student's T and Mann-Whitney U tests in case of quantitative variables of normal and non-normal distribution, respectively. RESULTS: Fifteen kidney transplants were performed in the period described. Delayed renal function (DRF) was seen in 7.5% of patients, and 26.6% showed data of acute rejection; no patient presented COVID-19 disease. Comparative analysis showed a remarkable increase in the number of transplants in comparison with previous periods (15 vs 5.6), at the expense of donors from outside Cantabria (93.3%). We found no statistically significant differences in terms of cold ischemia time (p = 0.77), DRF (p = 0.73), need for dialysis (p = 0.54), or appearance of post-surgical complications (p = 0.61). CONCLUSIONS: The evolution of the pandemic in our region, and the adoption of strict protective measures has allowed the early and safe resumption of the renal transplantation program, increasing the number of transplants performed compared to previous years and maintaining comparable early post-operative results


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Transplante de Rim/métodos , Pandemias , Segurança do Paciente , Infecções por Coronavirus/epidemiologia , Pneumonia Viral/epidemiologia , Estudos Retrospectivos , Complicações Pós-Operatórias , Estatísticas não Paramétricas , Infecções por Coronavirus/prevenção & controle , Pneumonia Viral/prevenção & controle
12.
Actas urol. esp ; 41(1): 1-10, ene.-feb. 2017. ilus
Artigo em Espanhol | IBECS | ID: ibc-158957

RESUMO

Introducción: La enfermedad estenótica de la uretra posterior es una complicación no menor de los tratamientos aplicados en la hipertrofia benigna de próstata, cáncer de próstata (CaP) y tras neovejigas ortotópicas, pudiendo comprometer el resultado funcional miccional. Objetivos: Identificar los factores etiológicos de la enfermedad estenótica de causa no traumática de la uretra posterior, su prevención y su tratamiento. Adquisición de la evidencia: Se han revisado los artículos indexados en PubMed en idiomas inglés y español de las secuelas estenóticas de la uretra posterior tras los tratamientos aplicados en el cáncer de próstata, en la cirugía de la hipertrofia benigna de próstata y de las neovejigas ortotópicas. Se han incluido estudios de cohortes, revisiones de artículos y estudios prospectivos y retrospectivos, con el mayor número de casos. Síntesis de la evidencia: La evidencia obtenida en la bibliografía es que la frecuencia de aparición de dichas estenosis no es despreciable, que su morbilidad puede ser importante y que debe sospecharse tras la pérdida de la calidad miccional. Su prevención empieza con una apropiada técnica quirúrgica y/o radioterápica. Aunque el tratamiento endoscópico es el preferido inicialmente, en ocasiones se requieren uretroplastias complejas abiertas, siendo la incontinencia urinaria la secuela más importante, pudiendo requerir implantes de esfínteres artificiales. Conclusiones: Las estenosis no traumáticas de la uretra posterior son complicaciones que pueden ser importantes, llegando a comprometer el éxito del tratamiento inicial de la enfermedad de base y requiriendo en ocasiones de cirugías complejas que pueden llevar a la incontinencia


Introduction: Posterior urethral stenoses and contractures are complications after treatment of benign prostatic hyperplasia (BPH), localised prostate cancer (PCa), and orthotopic neobladder formation, compromising prognosis and functional outcomes. Objectives: To identify factors related to aetiology, prevention and treatment of non-traumatic posterior urethral stenosis and contractures. Acquisition of evidence: Review of the published evidence related to posterior urethral stenosis and contractures after PCa treatment, BPH therapies and orthotopic neobladder formation. PubMed database search with English and Spanish papers considered. Cohort studies, case series, prospective and retrospective studies and review papers were included. Synthesis of evidence: Posterior urethral stenoses and contractures are common, leading to significant morbidity. A worsening on voiding quality should rise some concerns. Careful surgical and/or radiotherapic techniques prevent their development. Endoscopic therapies are the initial approach, with complex urethroplasties often required. Subsequent urinary incontinence, the most important sequelae, may need artificial sphincters. Conclusions: Non-traumatic posterior urethral stenoses could be important complications, potentially compromising the outcomes of initial therapy. They could require complex surgeries leading to urinary incontinence


Assuntos
Humanos , Masculino , Estreitamento Uretral/diagnóstico , Obstrução Uretral/diagnóstico , Complicações Pós-Operatórias/diagnóstico , Neoplasias da Próstata/complicações , Hiperplasia Prostática/complicações
13.
Actas Urol Esp ; 41(1): 1-10, 2017.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-27133545

RESUMO

INTRODUCTION: Posterior urethral stenoses and contractures are complications after treatment of benign prostatic hyperplasia (BPH), localised prostate cancer (PCa), and orthotopic neobladder formation, compromising prognosis and functional outcomes. OBJECTIVES: To identify factors related to aetiology, prevention and treatment of non-traumatic posterior urethral stenosis and contractures. ACQUISITION OF EVIDENCE: Review of the published evidence related to posterior urethral stenosis and contractures after PCa treatment, BPH therapies and orthotopic neobladder formation. PubMed database search with English and Spanish papers considered. Cohort studies, case series, prospective and retrospective studies and review papers were included. SYNTHESIS OF EVIDENCE: Posterior urethral stenoses and contractures are common, leading to significant morbidity. A worsening on voiding quality should rise some concerns. Careful surgical and/or radiotherapic techniques prevent their development. Endoscopic therapies are the initial approach, with complex urethroplasties often required. Subsequent urinary incontinence, the most important sequelae, may need artificial sphincters. CONCLUSIONS: Non-traumatic posterior urethral stenoses could be important complications, potentially compromising the outcomes of initial therapy. They could require complex surgeries leading to urinary incontinence.


Assuntos
Complicações Pós-Operatórias , Estreitamento Uretral , Procedimentos Cirúrgicos Urológicos , Humanos , Masculino , Complicações Pós-Operatórias/diagnóstico , Complicações Pós-Operatórias/etiologia , Complicações Pós-Operatórias/terapia , Prostatectomia , Estreitamento Uretral/diagnóstico , Estreitamento Uretral/etiologia , Estreitamento Uretral/terapia
14.
Actas urol. esp ; 40(9): 539-548, nov. 2016. ilus, tab
Artigo em Espanhol | IBECS | ID: ibc-157256

RESUMO

Introducción: Las lesiones de la uretra posterior (UP) se asocian a fractura de pelvis (FP) en un 5-10%. La UP se fija a la pelvis ósea mediante los ligamentos pubo-prostáticos y la membrana perineal, esto explica que la disrupción del anillo pelviano pueda lesionar la uretra a este nivel. Objetivos: Identificar los casos sospechosos de traumatismo de UP, cómo realizar el diagnóstico y su manejo inmediato o diferido. Adquisición de la evidencia: Búsqueda en PubMed de artículos relacionados con lesiones traumáticas de UP, escritos tanto en inglés como en español. Se revisaron las publicaciones relevantes incluyendo revisiones de la literatura y capítulos de libros relacionados con el tema. Síntesis de la evidencia: Ante un paciente con FP siempre hay que descartar lesión de UP. El examen diagnóstico de elección es la uretrografía retrógrada, que junto con la gravedad del paciente determinará el manejo en la fase aguda y si el tratamiento se realizará de forma inmediata o diferida. El diagnóstico precoz y un manejo agudo correcto disminuyen las complicaciones asociadas, como la estenosis, la incontinencia urinaria y la disfunción eréctil. Conclusiones: A pesar de que la asociación de las lesiones de UP con FP es clásica, su manejo tanto inmediato como diferido sigue siendo controvertido. Gracias al interés en aumento por la enfermedad uretral, cada vez se realizan más estudios que permiten acercarnos a un mejor manejo de estas lesiones


Introduction: The posterior urethral lesions are associated with pelvis fractures in 5-10% of cases. The posterior urethra is attached to the pelvis bone by puboprostatic ligaments and the perineal membrane, which explains why disruption of the pelvic ring can injure the urethra at this level. Objectives: To identify suspected cases of posterior urethral trauma and to perform the diagnosis and its immediate or deferred management. Acquisition of evidence: Search in PubMed of articles related to traumatic posterior urethral lesions, written in English or Spanish. We reviewed the relevant publications including literature reviews and chapters from books related to the topic. Synthesis of the evidence: With patients with pelvis fractures, we must always rule out posterior urethral lesions. The diagnostic examination of choice is retrograde urethrography, which, along with the severity of the condition, will determine the management in the acute phase and whether the treatment will be performed immediately or deferred. Early diagnosis and proper acute management decrease the associated complications, such as strictures, urinary incontinence and erectile dysfunction. Conclusions: Despite the classical association between posterior urethral lesions and pelvic fractures, the management of those lesions (whether immediate or deferred) remains controversial. Thanks to the growing interest in urethral disease, there are an increasing number of studies that help us achieve better management of these lesions


Assuntos
Humanos , Uretra/lesões , Pelve/lesões , Traumatismos Abdominais/complicações , Procedimentos de Cirurgia Plástica/métodos , Fixação Interna de Fraturas/métodos , Resultado do Tratamento
15.
Actas Urol Esp ; 40(9): 539-548, 2016 Nov.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-27174572

RESUMO

INTRODUCTION: The posterior urethral lesions are associated with pelvis fractures in 5-10% of cases. The posterior urethra is attached to the pelvis bone by puboprostatic ligaments and the perineal membrane, which explains why disruption of the pelvic ring can injure the urethra at this level. OBJECTIVES: To identify suspected cases of posterior urethral trauma and to perform the diagnosis and its immediate or deferred management. ACQUISITION OF EVIDENCE: Search in PubMed of articles related to traumatic posterior urethral lesions, written in English or Spanish. We reviewed the relevant publications including literature reviews and chapters from books related to the topic. SYNTHESIS OF THE EVIDENCE: With patients with pelvis fractures, we must always rule out posterior urethral lesions. The diagnostic examination of choice is retrograde urethrography, which, along with the severity of the condition, will determine the management in the acute phase and whether the treatment will be performed immediately or deferred. Early diagnosis and proper acute management decrease the associated complications, such as strictures, urinary incontinence and erectile dysfunction. CONCLUSIONS: Despite the classical association between posterior urethral lesions and pelvic fractures, the management of those lesions (whether immediate or deferred) remains controversial. Thanks to the growing interest in urethral disease, there are an increasing number of studies that help us achieve better management of these lesions.


Assuntos
Fraturas Ósseas/complicações , Ossos Pélvicos/lesões , Uretra/lesões , Humanos , Ferimentos e Lesões/diagnóstico , Ferimentos e Lesões/terapia
16.
Actas urol. esp ; 39(6): 387-391, jul.-ago. 2015. tab, ilus
Artigo em Espanhol | IBECS | ID: ibc-139330

RESUMO

Objetivos: El carcinoma urotelial vesical variedad en nidos es extremadamente infrecuente, y tiene un comportamiento más agresivo que el resto de tumores de vejiga. El objetivo principal de este estudio es analizar si su comportamiento en nuestro medio es tan agresivo como lo descrito en la literatura. Material y método: Revisión de 12 casos diagnosticados de carcinoma urotelial vesical variedad en nidos y análisis de las características tumorales, opciones de tratamiento, análisis de recurrencia y supervivencia de la enfermedad entre enero de 1997 y diciembre del 2010 en nuestra institución. Resultados: El 50% de los casos tuvo un estadio tumoral ≥ T2, siendo el grado de diferenciación G2 (50%) o G3 (50%). Tras el resultado anatomopatológico de la primera resección transuretral (RTU) vesical en 5 pacientes se practicó cistoprostatectomía radical, 3 una segunda RTU y 4 pacientes solo con tratamiento quimioterápico (QT) posterior y/o radioterapia (RT). De los 12 casos 5 (41,7%) fallecieron por causa tumoral y 3 (25%) por otras causas (sepsis urinaria, insuficiencia respiratoria, insuficiencia renal). Con una mediana de seguimiento de 40 meses la supervivencia global fue del 50% y la supervivencia cáncer específica del 65,6%. Conclusiones: El carcinoma urotelial vesical variedad en nidos es un tumor que se presenta en estadios avanzados, con altas tasas de recurrencias y mortalidad a pesar del uso de diferentes herramientas de tratamiento. No existe hasta la fecha una guía de práctica clínica para esta variedad de tumor urotelial


Objectives: The nested variant of bladder transitional cell carcinoma is extremely rare and has a different biological behavior to other bladder tumors. The aim of this study is to analize if their behavior is as aggressive as has been described in the literature. Material and method: Review of 12 diagnosed cases with nested variant of bladder transitional cell carcinoma and analysis of demographic characteristics, clinical presentation, tumor characteristics, treatment options, analysis of recurrence and cancer-specific survival between January 1997 and December 2010 in our hospital. Results: 50% of the cases had a pathologic stage ≥ T2, with grade of differentiation G2 (50%) or G3 (50%). After the pathological result of the TUR (transurethral resection) Bladder, 5 cases underwent radical cystoprostatectomy, 3 a second TUR bladder and 4 cases with treatment chemotherapy and/or radiotherapy (RT). Five out of 12 cases (41.7%) died due to bladder cancer and 3 died (25%) of other causes (urinary sepsis, respiratory failure, renal failure). With a median follow up of 40 months, the overall survival was 50% and cancer-specific survival of 65.6%. Conclusions: The nested variant of bladder transitional cell carcinoma is a disease with an advanced-stage presentation, with high recurrence and mortality rates despite the use of different treatments. So far there is not a clinical practice guideline for this variety of urothelial tumor


Assuntos
Humanos , Carcinoma de Células de Transição/epidemiologia , Neoplasias da Bexiga Urinária/epidemiologia , Análise de Sobrevida , Invasividade Neoplásica/patologia , Estudos Retrospectivos
17.
Actas Urol Esp ; 39(6): 387-91, 2015.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-25670479

RESUMO

OBJECTIVES: The nested variant of bladder transitional cell carcinoma is extremely rare and has a different biological behavior to other bladder tumors. The aim of this study is to analize if their behavior is as aggressive as has been described in the literature. MATERIAL AND METHOD: Review of 12 diagnosed cases with nested variant of bladder transitional cell carcinoma and analysis of demographic characteristics, clinical presentation, tumor characteristics, treatment options, analysis of recurrence and cancer-specific survival between January 1997 and December 2010 in our hospital. RESULTS: 50% of the cases had a pathologic stage ≥T2, with grade of differentiation G2 (50%) or G3 (50%). After the pathological result of the TUR (transurethral resection) Bladder, 5 cases underwent radical cystoprostatectomy, 3 a second TUR bladder and 4 cases with treatment chemotherapy and/or radiotherapy (RT). Five out of 12 cases (41.7%) died due to bladder cancer and 3 died (25%) of other causes (urinary sepsis, respiratory failure, renal failure). With a median follow up of 40 months, the overall survival was 50% and cancer-specific survival of 65.6%. CONCLUSIONS: The nested variant of bladder transitional cell carcinoma is a disease with an advanced-stage presentation, with high recurrence and mortality rates despite the use of different treatments. So far there is not a clinical practice guideline for this variety of urothelial tumor.


Assuntos
Carcinoma de Células de Transição/patologia , Neoplasias da Bexiga Urinária/patologia , Idoso , Carcinoma de Células de Transição/mortalidade , Carcinoma de Células de Transição/cirurgia , Carcinoma de Células de Transição/terapia , Quimiorradioterapia , Quimioterapia Adjuvante , Terapia Combinada , Cistectomia , Feminino , Hematúria/etiologia , Humanos , Estimativa de Kaplan-Meier , Masculino , Pessoa de Meia-Idade , Metástase Neoplásica , Recidiva Local de Neoplasia , Prognóstico , Prostatectomia , Fumar/epidemiologia , Neoplasias da Bexiga Urinária/mortalidade , Neoplasias da Bexiga Urinária/cirurgia , Neoplasias da Bexiga Urinária/terapia
18.
Arch Esp Urol ; 67(9): 764-9, 2014 Nov.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-25407150

RESUMO

OBJECTIVES: To analyze the influence of the different pre - cystectomy factors, both clinical and pathological, in the follow up of patients with no residual tumor ( pT0) in the pathological examination of the radical cystectomy specimen as predictors of tumor recurrence. Secondly we intend to compare overall survival, disease free survival and cancer-specific survival with the rest of cystectomy patients in our series. METHODS: Between 1985 and 2010, radical cystectomy was performed in 280 patients with bladder cancer, being 41 pT0 (14.6%). We analyzed potential predictors for overall survival and disease-free survival: age, sex , number of transurethral resections of bladder tumor before cystectomy , tumor type , tumor grade, tumor stage, tumor size, number of tumors, associated Cis and previous instillations. We used univariate analysis of Cox regression. Survival analysis was performed using Kaplan - Meier curves and log-rank test. RESULTS: Mean age was 61.7 years and 37 patients were males (90.2%). Stages before cystectomy were pT1 in eight (19.5%) , pT2 in 31 (75.6%) and Cis in two (4.9 %) with tumor grade III in 37 (90.2%). Cystectomy specimens revealed the presence of papillary transitional cell carcinoma in 38 (92.7%) cases. The median number of pre-cistectomy-TURBT was one. Eleven patients (26.8%) received intravesical instillations. Six patients (14.63 %) had tumor recurrence and 10 (24.4 %) died from causes unrelated to the disease. None of the variables analyzed was statistically significant in the univariate analysis as a predictor of tumor recurrence. With a median follow up of 70 months (3-272) disease-free survival and overall survival at five years were 85.9% and 72.8% respectively. Compared to the non pT0 cystectomies in our series, pT0 had a statistically significant difference for better recurrence-free survival (63.4 % and 36.8%, respectively in pT0 and no-pT0 patients) (p〈0,05). CONCLUSIONS: According to the results, we have found a better outcome for pT0 patients after cystectomy compared to those with residual tumor. We have not found any pre - cystectomy predictive factor related to disease-free survival and overall survival.


Assuntos
Carcinoma de Células de Transição , Cistectomia , Neoplasias da Bexiga Urinária , Carcinoma de Células de Transição/cirurgia , Intervalo Livre de Doença , Humanos , Masculino , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Neoplasia Residual , Estudos Retrospectivos , Neoplasias da Bexiga Urinária/cirurgia
19.
Arch. esp. urol. (Ed. impr.) ; 67(9): 764-769, nov. 2014. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-129943

RESUMO

OBJETIVOS: Analizar la influencia de los diferentes factores pre-cistectomía tanto clínicos como anatomopatológicos, en el seguimiento de pacientes con estudio anatomopatológico de la pieza de cistectomía radical con ausencia de tumor residual (pT0), como factores predictivos de recurrencia tumoral en estos pacientes. En segundo lugar, pretendemos comparar la supervivencia global, supervivencia libre de enfermedad y la supervivencia cáncer específica con las del resto de pacientes cistectomizados de nuestra serie. MÉTODOS: Entre 1985-2010 se intervinieron 280 pacientes de cistectomía radical por causa tumoral, de los cuales 41 fueron pT0 (14,6%). Se exploraron los potenciales factores predictores para supervivencia global y supervivencia libre de enfermedad: edad, sexo, número de resecciones transuretrales de vejiga previas a la cistectomía, tipo tumoral, grado, estadio, tamaño tumoral, número de tumores, Cis asociado e instilaciones previas usando un análisis univariado de regresión de Cox. El análisis de supervivencia se realizó mediante curvas de Kaplan-Meier y Log-Rank test. RESULTADOS: La edad media fue 61,7 años y 37 (90,2%) de ellos fueron varones. Los estadios previos a la cistectomía fueron pT1 en ocho (19,5%), pT2 en 31 (75,6%), y Cis en dos (4,9%), con un grado tumoral III en 37 (90,2%). La anatomía patológica (AP), reveló la presencia de carcinoma transicional papilar en 38 (92,7%) casos. La mediana de RTU-V previas fue una. Habían recibido instilaciones endovesicales 11 (26,8%) pacientes. Seis pacientes (14,63%) presentaron recidiva tumoral y diez (24,4%) fallecieron por causas ajenas a la enfermedad. Ninguna de las variables analizadas resultó ser estadísticamente significativa en el estudio univariado como predictora de recurrencia tumoral. Con una mediana de seguimiento de 70 meses (3-272), la supervivencia libre de enfermedad y supervivencia global fueron del 85,9% y del 72,8% a los cinco años respectivamente. Comparando con las cistectomías no pT0 de nuestra serie, los pT0 presentaban una diferencia estadísticamente significativa en cuanto a mayor supervivencia libre de recurrencia (63,4% y 36,8% respectivamente en pacientes no pT0) (p<0,05). CONCLUSIONES: En nuestra serie, al análisis encontramos que los resultados clínicos de los pacientes pT0 tras la cistectomía son mejores que los de los pacientes con tumor residual. No habiendo encontrado factores pronósticos pre-cistectomía predictivos para la supervivencia libre de enfermedad


OBJETIVES: To analyze the influence of the different pre-cystectomy factors, both clinical and pathological, in the follow up of patients with no residual tumor ( pT0 ) in the pathological examination of the radical cystectomy specimen as predictors of tumor recurrence. Secondly we intend to compare overall survival, disease free survival and cancer-specific survival with the rest of cystectomy patients in our series. METHODS: Between 1985 and 2010, radical cystectomy was performed in 280 patients with bladder cancer, being 41 pT0 (14.6%). We analyzed potential predictors for overall survival and disease-free survival: age, sex , number of transurethral resections of bladder tumor before cystectomy , tumor type , tumor grade, tumor stage, tumor size, number of tumors, associated Cis and previous instillations. We used univariate analysis of Cox regression. Survival analysis was performed using Kaplan - Meier curves and log-rank test. RESULTS: Mean age was 61.7 years and 37 patients were males (90.2%). Stages before cystectomy were pT1 in eight (19.5%) , pT2 in 31 (75.6%) and Cis in two (4.9 %) with tumor grade III in 37 (90.2%). Cystectomy specimens revealed the presence of papillary transitional cell carcinoma in 38 (92.7%) cases. The median number of pre-cistectomy-TURBT was one. Eleven patients (26.8%) received intravesical instillations. Six patients (14.63 %) had tumor recurrence and 10 (24.4 %) died from causes unrelated to the disease. None of the variables analyzed was statistically significant in the univariate analysis as a predictor of tumor recurrence. With a median follow up of 70 months (3-272) disease-free survival and overall survival at five years were 85.9% and 72.8% respectively. Compared to the non pT0 cystectomies in our series, pT0 had a statistically significant difference for better recurrence-free survival (63.4 % and 36.8%, respectively in pT0 and no-pT0 patients) (p < 0,05) CONCLUSIONS: According to the results, we have found a better outcome for pT0 patients after cystectomy compared to those with residual tumor. We have not found any pre - cystectomy predictive factor related to disease-free survival and overall survival


Assuntos
Humanos , Cistectomia , Neoplasias da Bexiga Urinária/cirurgia , Complicações Pós-Operatórias/epidemiologia , Intervalo Livre de Doença , Risco Ajustado/métodos , Fatores de Risco , Estudos Retrospectivos
20.
Actas urol. esp ; 38(6): 413-418, jul.-ago. 2014. tab, ilus
Artigo em Espanhol | IBECS | ID: ibc-125193

RESUMO

Introducción: La cirugía radical pélvica requiere de una derivación urinaria, incontinente o continente. Existen numerosas técnicas, siendo la más utilizada la neovejiga ortotópica. En ocasiones, cuando esta derivación no es posible o no está indicada, un reservorio urinario continente es una buena alternativa. El objetivo de este trabajo es presentar nuestra experiencia con el reservorio urinario continente de Indiana. Material y métodos: La serie está constituida por 85 pacientes, 66 mujeres y 19 hombres, con una edad media de 56 años (31 a 77 años). Las variables analizadas fueron el tiempo operatorio, la pérdida sanguínea, la tasa de transfusión, la estancia hospitalaria y las complicaciones perioperatorias. Resultados: La indicación principal fue la resolución de complicaciones derivadas del tratamiento del cáncer cérvico-uterino en 49 casos. La duración media de la derivación urinaria fue de 110,5 min (rango 80-130 min). El sangrado promedio fue de 450 cc (rango 100-1.000 cc). Hubo complicaciones postoperatorias inmediatas en 16 pacientes (18,85%), todos tratados médicamente. Un paciente tuvo una fístula anastomótica. La estancia hospitalaria fue 19 días (rango 5-60 días). No hubo mortalidad en la serie. Complicaciones alejadas ocurrieron en 26 pacientes (32%): estenosis de la anastomosis ureteral en 11 casos, estenosis del estoma cutáneo en 9 casos y litiasis del reservorio en 6 casos. Conclusión: El reservorio urinario continente y cateterizable de Indiana es una opción válida para el tratamiento de neoplasias urológicas o ginecológicas, y también para el manejo de enfermedades pélvicas relacionadas con complicaciones del tratamiento de cánceres pélvicos


Introduction: Radical pelvic surgery requires continent or incontinent urinary diversion. There are many techniques, but the orthotopic neobladder is the most used. A continent catheterizable urinary reservoir is sometimes a good alternative when this derivation is not possible or not indicated. This paper has aimed to present our experience with the Indiana pouch continent urinary reservoir. Materials and methods: The series is made up of 85 patients, 66 women and 19 men, with a mean age of 56 years (31-77 years). Variables analyzed were operating time, estimated blood loss, transfusion rate, hospital stay and peri-operatory complications. Results: The main indication in 49 cases was resolution of complications related to the treatment of cervical cancer. Average operation time was 110.5 minutes (range 80-130 minutes). Mean blood loss was 450 cm3 (100-1000 cm3). Immediate postoperative complications, all of which were treated medically, occurred in 16 patients (18.85%). One patient suffered anastomotic leakage. Hospital stay was 19 days (range 5-60 days) and there was no mortality in the series. Late complications occurred in 26 patients (32%), these being ureteral anastomotic stenosis in 11 cases, cutaneous stoma stenosis in 9 cases and reservoir stones in 6 cases. Conclusion: The Indiana continent catheterizable urinary reservoir is a valid option for the treatment of both urological and gynecological malignancies as well as for the management of pelvic morbidity related to the treatment of pelvic cancers


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Idoso , Neoplasias da Bexiga Urinária/cirurgia , Coletores de Urina , Exenteração Pélvica/métodos , Neoplasias do Colo do Útero/cirurgia , Derivação Urinária/métodos , Complicações Pós-Operatórias/epidemiologia , Cateterismo Urinário/métodos , Neoplasias Pélvicas/cirurgia
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