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Molecules ; 10(9): 1190-6, 2005 Sep 30.
Artigo em Inglês | MEDLINE | ID: mdl-18007385

RESUMO

The behavioural responses of the haematophagous bug Triatoma infestans towards some previously identified components of its faeces: 4-methylquinazoline, 2,4- dimethylquinazoline and their mixtures were evaluated using a video tracking system. Fifth instar nymphs and females but not males were significantly attracted to polyethylene glycol formulations of 4-methyl + 2,4-dimethylquinazoline (50 microg each). Fifth instar nymphs were also attracted to 4-methylquinazoline alone (50 microg) but females were only attracted by the mixture of both methyl quinazolines (50 microg each). Syntheses of both methyl quinazolines were carried out starting from 2-aminoacetophenone by modifying the conditions of reported procedures.


Assuntos
Comportamento Animal/efeitos dos fármacos , Quinazolinas/farmacologia , Triatoma/efeitos dos fármacos , Animais , Bioensaio , Feminino , Masculino , Ninfa/efeitos dos fármacos , Quinazolinas/química
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