[Urinary lithiasis as a systemic disease.] / La litiasis urinaria como enfermedad sistémica.

Urinary lithiasis is a prevalent disorder of uncertain origin which provokes health problems through potential harm to the urinary system, renal parenchyma or the body as a whole, with a frequent trend to relapse. Historically urinary calculi have been studied and treated as an isolated disease but nowadays we know more about their connection with other pathological entities. In a small percentage of patients, diseases like primary hyperparathyroidism, tubular renal acidosis, inflammatory bowel disease or bariatric surgery have a fairly well studied physiopathological link with kidney stones. However, papers have been published recently describing connections between prevalent diseases such as bone disease or metabolic syndrome and nephrolithiasis. Attempts to prevent or treat these affections can possibly influence the other's prevalence since their trend to increase is clear in western countries.

La litiasis urinaria como enfermedad sistémica / Urinary lithiasis as a systemic disease

La litiasis urinaria es una patología prevalente de origen desconocido, que acarrea problemas al paciente tanto por el potencial daño a la vía urinaria, parénquima renal y organismo en su conjunto como por la tendencia frecuente de esta enfermedad a la recidiva. Historicamente se ha estudiado y tratado como una alteración aislada pero hoy en día cada vez conocemos mas sus conexiones con un conjunto de entidades patológicas con las que frecuentemente concurre. En un pequeño porcentaje de pacientes, enfermedades como el hiperparatiroidismo primario y la acidosis tubular renal tienen una clara correlación etiológica con la litiasis así como enfermedades inflamatorias digestivas y cirugía bariatrica. Sin embargo la conexión entre enfermedades frecuentes en la población, como la osteoporosis, el síndrome metabólico y la nefrolitiasis está en estudio, por si su prevención puede contribuir a frenar la tendencia al aumento de la incidencia y prevalencia de estas patologías en la sociedad occidental en las últimas décadas

Urinary lithiasis is a prevalent disorder of uncertain origin which provokes health problems through potential harm to the urinary system, renal parenchyma or the body as a whole, with a frequent trend to relapse. Historically urinary calculi have been studied and treated as an isolated disease but nowadays we know more about their connection with other pathological entities. In a small percentage of patients, diseases like primary hyperparathyroidism, tubular renal acidosis, inflammatory bowel disease or bariatric surgery have a fairly well studied physiopathological link with kidney stones. However, papers have been published recently describing connections between prevalent diseases such as bone disease or metabolic syndrome and nephrolithiasis. Attempts to prevent or treat these affections can possibly influence the other´s prevalence since their trend to increase is clear in western countries