Comparison between macular pigment optical density measurements using two-wavelength autofluorescence and heterochromatic flicker photometry techniques.

PURPOSE: The association of macular pigment (MP) with age-related macular degeneration has been extensively studied in recent years, and interest in a rapid, objective, and accurate technique to measure MP optical density (MPOD) has increased. The purpose of this study was to compare the MPOD values at specific loci around the fovea using the heterochromatic flicker photometry (HFP) and the two-wavelength autofluorescence (AF) methods in a young, healthy population. METHODS: Ten patients (20 eyes) were enrolled. Subjects with any ocular or systemic disease were excluded. All patients underwent HFP and AF examination. The AF examination was performed using a modified scanning laser ophthalmoscope. Values for both devices were measured at four eccentricities around the fovea (0.25 degrees , 0.5 degrees, 1.0 degrees, and 1.75 degrees). Each eye was tested three times with each METHOD: Statistical analysis was based on paired t-test and linear regression analysis. RESULTS: At all retinal eccentricities, the HFP values were consistently lower than the HRA values (P < 0.001). There was, however, a significant correlation at almost all locations. The strongest correlation between two methods was found at 1.75 degrees from the center of the fovea (r = 0.73). CONCLUSIONS: The modified-HRA AF method for MPOD generated results that were highly correlated with the standard HPF method but consistently higher at all eccentricities. These findings suggest that HRA can be reliably used in patients unable to perform HPF, which is important for wider clinical application of MP testing.

Pigmentos maculares / Macular pigments

A luteína e a zeaxantina são pigmentos amarelos que se localizam na mácula. Devido à sua localização, diminuem e filtram a quantidade de luz principalmente azul que chega aos fotorreceptores, atuam como antioxidantes e podem melhorar a qualidade visual. Esta é uma revisão do seu mecanismo de incorporação, ação, possíveis aplicações e conhecimento científico a respeito.

Lutein and Zeaxanthin are yellow pigments located at the macula. Because of your location macular pigments decrease and filter the amount of blue light that reach photoreceptors, protect the outer retina from oxidative stress and may improve the vision quality. This is a review regarding incorporation mechanism, function and knowledge update.

[Macular pigments]. / Pigmentos maculares.

Lutein and Zeaxanthin are yellow pigments located at the macula. Because of your location macular pigments decrease and filter the amount of blue light that reach photoreceptors, protect the outer retina from oxidative stress and may improve the vision quality. This is a review regarding incorporation mechanism, function and knowledge update.

Hemorragia de disco óptico possivelmente secundária a descolamento espontâneo do vítreo posterior / Optic disc haemorrhage possibly secondary to posterior vitreous detachment

Descreve o diagnóstico e conduta em um caso de hemorragia de disco óptico possivelmente secundária a descolamento espontâneo do vítreo posterior. Relata um caso de hemorragia de disco óptico possivelmente secundária a descolamento espontâneo do vítreo posterior, discutindo os aspectos diagnósticos, prognósticos e conduta oftalmológica.Observou-se regressão da hemorragia do disco após 6h de evolução do quadro sem sinais de recidiva durante os registros subseqüentes. A Oftalmoscopia com Laser de Varredura mostrou-se como um avançado método alternativo e eficaz no diagnóstico e seguimento do descolamento vítreo.

To describe the diagnosis and management of a optic disc haemorrhage probably caused by an acute and spontaneous posterior vitreous detachment. A single case-report of an optic disc haemorrhage probably caused by an spontaneous posterior vitreous detachment, in order to discuss the diagnosis, management and prognosis. Optic disc haemorrhage regression was observed after 6 hours of evolution without relapsing signals during the subsequent registers. The Scanning Laser Ophthalmoscopy revealed as an advanced alternative and efficient method in the vitreous detachment diagnosis and follow up.

Seguimento dinâmico dos níveis de paratormônio nos pacientes em diálise tratados com calcitriol / Dynamic follow up of the parathormone levels in dialysis patients treated with calcitriol

O hiperparatireoidismo secundário é uma complicação cumum na Insuficiência Renal Crônica e a deficiência de vitamina D tem papel importante para o desenvolvimento dessa enfermidade. O objetivo do presente estudo foi acompanhar prospectivamente no período de doze meses os níveis séricos de paratormônio, cálcio iônico e fósforo nos pacientes em tratamento dialítico. Ao final desse período foram feitas novas dosagens e comparadas com os valores anteriormente obtidos após a administração de calcitriol