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1.
Med Phys ; 49(10): 6599-6608, 2022 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-35942614

RESUMO

PURPOSE: Microwave imaging of breast cancer is considered and a new microwave imaging prototype including the imaging algorithm, the antenna array, and the measurement configuration is presented. The prototype aims to project the geometrical features of the anomalies inside the breast to a single-slice image at the coronal plane depending on the complex dielectric permittivity variation among the tissues to aid the diagnosis. METHODS: The imaging prototype uses a solid cylindrical dielectric platform, where a total of 24 optimized Vivaldi antennas are embedded inside to form a uniform circular antenna array. The center of the platform is carved to create a hollow part for placement of the breast and the multistatic, microwave scattering parameters are collected with the antenna array around the hollow center. The dielectric platform further enhances the microwave impedance matching against the breast fat tissue and preserves the vertical polarization during the measurements. In the imaging phase, a computationally efficient inverse electromagnetic scattering method-reverse time migration (RTM)-is considered and adapted in terms of scattering parameters to comply with the actual measurements. RESULTS: The prototype system is experimentally tested against tissue-mimicking breast phantoms with realistic dielectric permittivity profiles. The reconstructed single-slice images accurately determined the locations and the geometrical extents of the tumor phantoms. These experiments not only verified the microwave imaging prototype but also provided the first experimental results of the imaging algorithm. CONCLUSIONS: The presented prototype system implementing the RTM method is capable of reconstructing single-slice, nonanatomical images, where the hotspots correspond to the geometrical projections of the anomalies inside the breast.


Assuntos
Neoplasias da Mama , Imageamento de Micro-Ondas , Mama/patologia , Neoplasias da Mama/patologia , Diagnóstico por Imagem/métodos , Feminino , Humanos , Micro-Ondas , Imagens de Fantasmas
2.
Comput Biol Med ; 112: 103366, 2019 09.
Artigo em Inglês | MEDLINE | ID: mdl-31386972

RESUMO

The proper management of renal lithiasis presents a challenge, with the recurrence rate of the disease being as high as 46%. To prevent recurrence, the first step is the accurate categorization of the discarded renal calculi. Currently, the discarded renal calculi type is determined with the X-ray powder diffraction method which requires a cumbersome sample preparation. This work presents a new approach that can enable fast and accurate classification of discarded renal calculi with minimal sample preparation requirements. To do so, first, the measurements of the dielectric properties of naturally formed renal calculi are collected with the open-ended contact probe technique between 500 MHz and 6 GHz with 100 MHz intervals. Cole-Cole parameters are fitted to the measured dielectric properties with the generalized Newton-Raphson method. The renal calculi types are classified based on their Cole-Cole parameters as calcium oxalate, cystine, or struvite. The classification is performed using k-nearest neighbors (kNN) machine learning algorithm with the 10 nearest neighbors, where accuracy as high as 98.17% is achieved.


Assuntos
Cálculos Renais , Aprendizado de Máquina , Micro-Ondas , Feminino , Humanos , Cálculos Renais/classificação , Cálculos Renais/diagnóstico , Masculino
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