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G3 (Bethesda) ; 8(7): 2167-2172, 2018 07 02.
Artigo em Inglês | MEDLINE | ID: mdl-29789313

RESUMO

One of the most commonly used tools to compare protein or DNA sequences against databases is BLAST. We introduce a web tool that allows the performance of BLAST-searches of protein/DNA sequences in whole-genome sequenced bacteria/archaea, and displays a large amount of BLAST-results simultaneously. The circular bacterial replicons are projected as horizontal lines with fixed length of 360, representing the degrees of a circle. A coordinate system is created with length of the replicon along the x-axis and the number of replicon used on the y-axis. When a query sequence matches with a gene/protein of a particular replicon, the BLAST-results are depicted as an "x,y" position in a specially adapted plot. This tool allows the visualization of the results from the whole data to a particular gene/protein in real time with low computational resources.


Assuntos
Biologia Computacional/métodos , Software , Archaea/genética , Bactérias/genética , Bases de Dados Genéticas , Genoma Arqueal , Genoma Bacteriano , Genômica/métodos , Interface Usuário-Computador , Sequenciamento Completo do Genoma
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