Assuntos
Humanos , Feminino , Pessoa de Meia-Idade , Neoplasias Musculares/complicações , Neoplasias Musculares , Fluordesoxiglucose F18 , Neoplasias Pulmonares , Carcinoma , Tomografia por Emissão de Pósitrons/instrumentação , Tomografia por Emissão de Pósitrons/métodos , Biópsia/instrumentação , Biópsia/métodos , Músculo Esquelético/patologia , Músculo Esquelético , Medicina Nuclear/instrumentação , Medicina Nuclear/métodosAssuntos
Carcinoma Pulmonar de Células não Pequenas/diagnóstico por imagem , Carcinoma Pulmonar de Células não Pequenas/secundário , Radioisótopos de Flúor , Fluordesoxiglucose F18 , Neoplasias Pulmonares/patologia , Metástase Linfática/diagnóstico por imagem , Imagem Multimodal , Neoplasias Musculares/diagnóstico por imagem , Neoplasias Musculares/secundário , Tomografia por Emissão de Pósitrons , Compostos Radiofarmacêuticos , Tomografia Computadorizada por Raios X , Feminino , Humanos , Pessoa de Meia-Idade , Músculo Esquelético/diagnóstico por imagem , Estadiamento de NeoplasiasRESUMO
UNLABELLED: Quantification of myocardial perfusion scintigraphy is often performed to assist physicians in detecting coronary artery disease (CAD). Modern software and hardware packages provide improvements able to shorten scan time and/or reduce administered activity, without compromising image quality in radionuclide myocardial perfusion imaging (MPI). Recently, multifocal collimators were introduced with dedicated reconstruction software, named IQ-SPECT, able to shorten considerably scan time. The aim of our study was to compare this new protocol to the already validated standard ones. PATIENTS, METHODS: We enrolled 43 patients with suspected or diagnosed CAD. All patients underwent a two-days protocol radionuclide myocardial perfusion scan at rest and after a standard stress test (exercise or dipyridamole) after administering 99mTc-tetrofosmin. Images were acquired on a 2-head gamma camera and reconstructed with attenuation correction. All the images were scored using a 17-segments model by three experienced physicians, blind to clinical data and to acquisition and processing modality. RESULTS, CONCLUSION: No significant differences were recorded in perfusion scores on paired t-test and Wilcoxon among the full-time images reconstructed with standard protocol or IQ-SPECT, both overall on a 17-segments evaluation and when considering different territories of distribution. MPI with IQ-SPECT protocol can be acquired at about a quarter scan time without disagreement compared to full time scan acquisition performed with standard protocols.