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Int J Immunogenet ; 39(2): 161-9, 2012 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-22168175

RESUMO

The Antemoro are an ethnic group from the southeast coast of Madagascar who claims an Arab origin. Cultural signatures of an Arabo-Islamic influence have been found in this region. Nevertheless, their origins are very contentious. Through this study, we want to determine whether this ethnic group had a particular GM profile that differentiated it from other Malagasy populations, and whether there were detectable genetic traces of the Arabo-Islamic migration. The Gm polymorphisms of IgG immunoglobulins was analysed in a population of Antemoro (N = 85), two other Malagasy populations from northern Fiherena (N = 82) and southern Fiherena (N = 50) and in a Comorian population (N = 171). This last group was used to enlarge the database for genetic comparisons. Results revealed significant contributions from Africa (60%, 0.092 ≤F(ST) ≤ 0.280) and Southeast Asia (40%, 0.043 ≤ F(ST) ≤ 0.590) to the Antemoro genetic pool. No direct genetic relationships with the Middle East. These results bring new insights into the population history of Madagascar.


Assuntos
Árabes/genética , Emigração e Imigração , Genética Populacional , Alótipos Gm de Imunoglobulina/genética , Biologia Computacional , Bases de Dados Factuais , Frequência do Gene , Testes Genéticos , Variação Genética , Haplótipos , Humanos , Alótipos Gm de Imunoglobulina/sangue , Madagáscar/etnologia , Fenótipo , Vigilância da População
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