Temporal trend analysis of hospitalizations and in-hospital deaths due to female breast cancer in the state of Alagoas from 2009 to 2019: a cross-sectional study.

BACKGROUND: Breast cancer is a common neoplasm in women worldwide. Its varying patterns of incidence and clinical prognosis in Brazil make it an important and complex public health problem that needs to be solved. OBJECTIVES: To analyze the temporal dynamics of hospital admissions and deaths due to female breast cancer in the state of Alagoas, Brazil, from 2009 to 2019. DESIGN AND SETTING: Cross-sectional study including secondary data from hospital admissions and deaths due to female breast cancer in Alagoas. METHODS: A joinpoint regression model was constructed for temporal analysis of hospital admissions and deaths due to female breast cancer in Alagoas, over this period. The hospital information system of the Department of Informatics of the National Health System was used. RESULTS: There were 5,801 hospitalizations and 633 hospital deaths due to neoplasm in Alagoas over the period. The age group from 50 to 59 years old stood out, corresponding to 28.1% of hospitalizations and 31.1% of registered deaths. An increasing trend in the rate of hospital admissions was observed (average annual percentage change, AAPC = 14.0; P-value < 0.001), from 14.9/100,000 inhabitants in 2009 to 53.6 in 2019. There was a growth trend in the in-hospital mortality rate (AAPC = 19.8; P-value < 0.001), from 6.3% in 2009 to 11.0% in 2019. CONCLUSION: The results indicated an increasing trend of hospital admissions and mortality rates in the state of Alagoas, with a higher percentage of hospitalizations and deaths in the 50-59 age group.

Temporal trend analysis of hospitalizations and in-hospital deaths due to female breast cancer in the state of Alagoas from 2009 to 2019: a cross-sectional study

ABSTRACT BACKGROUND: Breast cancer is a common neoplasm in women worldwide. Its varying patterns of incidence and clinical prognosis in Brazil make it an important and complex public health problem that needs to be solved. OBJECTIVES: To analyze the temporal dynamics of hospital admissions and deaths due to female breast cancer in the state of Alagoas, Brazil, from 2009 to 2019. DESIGN AND SETTING: Cross-sectional study including secondary data from hospital admissions and deaths due to female breast cancer in Alagoas. METHODS: A joinpoint regression model was constructed for temporal analysis of hospital admissions and deaths due to female breast cancer in Alagoas, over this period. The hospital information system of the Department of Informatics of the National Health System was used. RESULTS: There were 5,801 hospitalizations and 633 hospital deaths due to neoplasm in Alagoas over the period. The age group from 50 to 59 years old stood out, corresponding to 28.1% of hospitalizations and 31.1% of registered deaths. An increasing trend in the rate of hospital admissions was observed (average annual percentage change, AAPC = 14.0; P-value < 0.001), from 14.9/100,000 inhabitants in 2009 to 53.6 in 2019. There was a growth trend in the in-hospital mortality rate (AAPC = 19.8; P-value < 0.001), from 6.3% in 2009 to 11.0% in 2019. CONCLUSION: The results indicated an increasing trend of hospital admissions and mortality rates in the state of Alagoas, with a higher percentage of hospitalizations and deaths in the 50-59 age group.

Clinical and epidemiological profile of COVID-19 in health professionals: a review of the literature.

Occupational exposure is an important source of coronavirus transmission among health professionals. The objective of this study is to review the literature on the clinical and epidemiological profile of health professionals infected by COVID-19. An integrative review was conducted based on searches of the LILACS, Medline, and PubMed databases using the following terms: medical workers, healthcare workers, healthcare personnel, and healthcare professionals combined with COVID-19, SARS-CoV-2, 2019-nCoV, n-CoV, and coronavirus, with the Boolean operators "AND" and "OR". A total of 710 publications were identified, 18 of which were selected for the review, totaling 2,208 infected health professionals in eight countries. It was observed that 67.4% (n = 1,489) of these professionals were women, and 39.4% of the population described in the 15 studies that provided information on occupation (n = 811) were nurses. Seven publications (n = 553) reported severity, among which the most prevalent category was mild/common (47.3% of cases; n = 213). The most common comorbidities were migraine (9.6%, n = 87 of 906), systemic arterial hypertension (5.5%, n = 78 of 1,427), and chronic obstructive pulmonary disease (3.7%, n = 52 of 1,399). The most common symptoms were coughing (34.3%, n = 597 of 1,740), headache (36.8%, n = 582 of 1,583), and myalgia (31.6%, n = 544 of 1,720). The most frequent radiological findings were bilateral involvement (34.5%, n = 139 of 403), ground glass (49%, n = 101 of 206), and bilateral pneumonia (77.4%, n = 65 of 84). The study found that the most often affected health professionals were female nursing professionals, the main symptom was coughing, and the most frequent comorbidity was migraine. The study's limitation is the small sample. There is a need for more studies with these professionals.