RESUMO
The analysis of the nucleoprotein gene of 77 Puumala hantavirus strains detected in human samples in France during 2012-2016 showed that all belonged to the Central European lineage. We observed 2 main clusters, geographically structured; one included strains with the Q64 signature and the other strains with the R64 signature.
Assuntos
Arvicolinae/virologia , Infecções por Hantavirus/virologia , Orthohantavírus/genética , Virus Puumala/genética , Animais , Análise por Conglomerados , França/epidemiologia , Genômica , Genótipo , Geografia , Orthohantavírus/isolamento & purificação , Infecções por Hantavirus/epidemiologia , Humanos , Filogenia , Virus Puumala/isolamento & purificação , ZoonosesRESUMO
We report detection of Seoul virus in 3 patients in France over a 2-year period. These patients accounted for 3 of the 4 Seoul virus infections among 434 hantavirus infections (1.7%) reported during this time. More attention should be given to this virus in Europe where surveillance has been focused mostly on Puumala and Dobrava-Belgrade hantaviruses.
Assuntos
Febre Hemorrágica com Síndrome Renal/diagnóstico , Febre Hemorrágica com Síndrome Renal/epidemiologia , Vírus Seoul , Adulto , Animais , Anticorpos Antivirais , França/epidemiologia , Febre Hemorrágica com Síndrome Renal/virologia , Humanos , Masculino , Ratos , Adulto JovemRESUMO
We report an infection with Tula virus in June 2015, leading to hospitalisation, in a patient living approximately 60 km east of Paris with no previous remarkable medical history. Clinical symptoms were limited to a fever syndrome with severe headache. The main laboratory findings included thrombocytopenia and elevated transaminase levels. Based on S (small) gene sequence analysis, the strain affecting the patient was closely related to strains detected in Central Europe, especially to a south-east German strain.
